Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,201 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04428489Enrolling by invitation
Follow-up for low blood counts without MDS
This study follows people with ongoing low blood counts (red cells, white cells, and/or platelets) to better understand their condition when it does not meet criteria for MDS. It may help improve how persistent blood count problems are evaluated over time.
Suzhou, JiangsuAges 18 years+ - NCT04398901Enrolling by invitation
Study of brain and development outcomes after Zika exposure
This study follows children to compare development in kids exposed to Zika before birth versus similar children not exposed. The goal is to understand what effects Zika exposure may have on early brain development and long-term outcomes.
Washington D.C., District of ColumbiaAges 3–7 - NCT04360265Enrolling by invitationPhase 3
Follow-up gene therapy study for MPS IIIA participants
This follow-up study looks at how a past gene therapy treatment (UX111) is affecting you over time. It mainly involves continued visits and safety checks, and it helps researchers understand long-term benefits and risks.
Columbus, OhioAges Any age - NCT03995342Enrolling by invitation
Study gut bacteria and frailty in older adults
This study looks at whether gut bacteria (intestinal flora) are linked to frailty in people age 65 and older. It will also test an intervention to see if changing gut bacteria can help reduce frailty.
Xi'an, ShaanxiAges 65 years+ - NCT03675724Enrolling by invitationPhase 2
Fisetin for frailty and inflammation in older adults
This trial studies whether fisetin, a supplement-like drug, can reduce frailty and inflammation in people age 70 and older. It may help improve health measures related to aging, but you must meet several safety and medication rules to join.
Rochester, MinnesotaAges 70 years+ - NCT03478670Enrolling by invitation
Registry follow-up for ADA-SCID patients treated with Strimvelis
This study keeps track of people with ADA-SCID (a rare immune system condition) who previously received Strimvelis or a related treatment. It helps doctors understand long-term outcomes and safety after treatment.
Milan, LombardyAges Any age - NCT03474237Enrolling by invitation
Study following people newly diagnosed with adrenal conditions
This study follows adults with a new adrenal diagnosis to learn how adrenal diseases behave over time. It may help doctors better understand these conditions and improve future care.
SeoulAges 19 years+ - NCT03417856Enrolling by invitation
Study skin and blood signs in ichthyosis
This study looks at “skin and blood biomarkers,” meaning measurable signs in the body, in people with ichthyosis to better understand the condition. It may help researchers find ways to track disease activity and evaluate future treatments.
Chicago, IllinoisAges 1–60 - NCT03385876Enrolling by invitation
Rapid whole genome sequencing for children with suspected genetic illness
This study quickly reads a child’s DNA using whole genome sequencing to look for genetic causes of symptoms. It may help families and doctors better understand an underlying genetic condition and guide medical care.
San Diego, CaliforniaAges Any age
Hear when a new Down Syndrome trial opens
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,201 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.