Clinical trials
E-Cig Use clinical trials
Below are recruiting e-cig use clinical trials, each written for real people, not researchers. We’re tracking 10 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04662658RecruitingPhase 1/Phase 2
Testing a special MRI gas scan of healthy lungs
This study tests a special MRI scan that uses a “hyperpolarized” gas to look at how well the lungs are working. It’s likely looking for safe imaging results and clear lung measurements in people without lung disease.
Charlottesville, VirginiaAges 18 years+ - NCT06860698Recruiting
E-cigarettes and blood vessel health in young adults
This study looks at how using e-cigarettes with nicotine affects the small blood vessels in young adults. It compares regular e-cigarette users to non-users to understand potential health impacts.
Richmond, VirginiaAges 18–29 - NCT06264154Recruiting
Can e-cigarette flavor help you quit smoking?
This study looks at whether the flavor of an e-cigarette can help people who keep smoking switch completely away from regular cigarettes. Participants will use e-cigarettes with different flavors for 6 weeks.
Philadelphia, PennsylvaniaAges 21 years+ - NCT07167225Recruiting
E-cigarette and cannabis co-use in young adults
This study looks at how using e-cigarettes and cannabis together affects exposure to harmful chemicals in young adults aged 18-25. It aims to understand the risks of co-use to help guide healthier choices.
Buffalo, New YorkAges 18–25 - NCT06862050Recruiting
Testing a smoking cessation program for tobacco users
This trial tests a program to help people quit tobacco. It focuses on offering support to daily tobacco users living in the Augusta or Central Savannah River Area.
Augusta, GeorgiaAges 18 years+ - NCT07039292Enrolling by invitation
Can e-cigarettes help reduce smoking?
This study tests whether e-cigarettes can help people who smoke but have not wanted to use other treatments. If you currently smoke and have declined traditional options like nicotine patches or quitlines, you may be able to join.
Charleston, South CarolinaAges 21 years+ - NCT06077240Recruiting
E-cigarettes vs pouches for quitting smoking
This study compares the effects of e-cigarettes and nicotine pouches on smoking habits and addiction. The goal is to see which method helps people smoke less and reduces their dependence on cigarettes.
New Haven, ConnecticutAges 21 years+ - NCT06543407Recruiting
Safer smoking options for people with mental illness
This study offers a way to reduce harm from smoking for people with mental health conditions who are not ready to quit. It tests if switching to a less harmful product can help improve health without requiring you to stop smoking completely.
Louisville, KentuckyAges 21 years+ - NCT06372899Recruiting
Switching to E-cigarettes or Nicotine Pouches for Smokers
This study tests whether switching to e-cigarettes or nicotine pouches can help smokers who have tried many times to quit. If you are a heavy smoker (at least 5 cigarettes a day) and have failed to quit before, this trial may offer a new way to reduce harm from smoking.
Philadelphia, PennsylvaniaAges 21 years+ - NCT05338801Recruiting
Study menthol effects in e-cigarette users
This study tests how menthol in e-cigarettes affects addiction-related feelings and exposure. You may be asked to visit a lab and temporarily stop vaping before each session.
Miami, FloridaAges 21–35
Hear when a new E-Cig Use trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for e-cig use?
- Yes. Clin2 currently lists 10 recruiting e-cig use studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a e-cig use trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a e-cig use trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.