Clinical trials
Engagement clinical trials
Below are recruiting engagement clinical trials, each written for real people, not researchers. We’re tracking 260 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06542250RecruitingPhase 1/Phase 2
Study of a new immune therapy for relapsed B-cell cancers
This trial tests a new drug (AZD5492) that helps your immune system attack a protein (CD20) on cancer cells. It's for people with B-cell cancers that have come back after at least 2 prior treatments.
La Jolla, CaliforniaAges 18 years+ - NCT06094543Recruiting
Improving access and adherence for overactive bladder treatment
This study compares two ways to help women with overactive bladder get treatment and stick with it. You might be able to join if you are a woman with ongoing OAB symptoms and haven't had certain treatments recently.
Redwood City, CaliforniaAges 18 years+ - NCT06814496RecruitingPhase 1/Phase 2
Radiation and immunotherapy combo for DLL3-positive cancers
This trial combines radiation with an immunotherapy drug called tarlatamab to treat cancers that make a protein called DLL3. The goal is to see if this combination works better than either treatment alone for people with certain types of lung cancer and other tumors that have not responded to prior therapy.
Tucson, ArizonaAges 18–99 - NCT06469307Recruiting
Patient advisory board for inclusive cancer research
This study is about forming a community advisory board (a group of patients and researchers) to help make cancer research at Dana-Farber more inclusive and fair. It is not a treatment trial—instead, you would review study materials and give your perspective.
Boston, MassachusettsAges 18 years+ - NCT07500363Recruiting
Helping caregivers engage in early autism therapy
This study looks at how to help caregivers of young children with autism engage more in early intervention. It connects you with a family or friend supporter who can help you, while the study team works with your therapist.
Sacramento, CaliforniaAges 1 year+ - NCT07216456Recruiting
Vaginal dilator therapy after pelvic radiation
This trial tests a program to help women use vaginal dilators after finishing pelvic radiation for cancers like cervical or anal cancer. It aims to improve vaginal health and quality of life.
Durham, North CarolinaAges 18 years+ - NCT03685045Recruiting
Hepatitis C treatment support for people using opioid substitutes
This trial is studying hepatitis C treatment approaches for adults who have a history of injecting drugs, especially those who have injected recently or are on opioid substitution therapy. If you fit the background criteria, the study may offer a treatment pathway and extra support to help you get hepatitis C treated.
Canberra, Australian Capital TerritoryAges 18 years+ - NCT03995082Recruiting
Survey study for newly diagnosed breast cancer patients
This study asks newly diagnosed breast cancer patients to fill out a survey about their experiences and symptoms. It may help the care team improve how they measure patient needs and experiences.
Denver, ColoradoAges Any age - NCT04515810Recruiting
Mobile app coaching for planning care after serious cancer
This study tests a mobile health app (PACT) to help people with advanced cancer talk and plan for future care. It may help you and a loved one stay engaged in advance care planning (planning what care you want and who should speak for you).
Manhasset, New YorkAges 18 years+ - NCT04811014RecruitingPhase 4
Helping young adults stop opioids after an emergency visit
This study offers an engagement program for young people who tested positive for opioids and meet criteria for opioid dependence. The goal is to help participants stop opioid use safely and learn whether this approach works well in the real-world emergency setting.
Houston, TexasAges 13–17 - NCT07170202Recruiting
Mindfulness for young heavy drinkers
This study tests if learning mindfulness can help young adults who drink heavily cut back on alcohol. You'll practice short, easy mindfulness exercises.
Tallahassee, FloridaAges 18–29 - NCT05267665Recruiting
Family-involved PTSD therapy coaching for Veterans
This study tests a brief way to include a Veteran’s family member to improve PTSD treatment results and help people stay engaged in care. It’s for Veterans who are just starting evidence-based PTSD therapy and have a closely involved family member who can participate too.
Boston, MassachusettsAges 18 years+ - NCT05365815Recruiting
Midwifery care program for Black pregnant people
This study tests a midwifery-style prenatal care model designed for pregnant people who self-identify as Black. It may help by offering more culturally centered support during early pregnancy and visits at the study clinic.
Chicago, IllinoisAges 15–49 - NCT05483166Recruiting
Parent coaching to support memory and behavior after childhood cancer
This pilot study tests a program that works with parents to support a child’s thinking, memory, and behavior after childhood cancer treatment. It may help by teaching parents strategies to support school and day-to-day functioning.
AarhusAges 10–17 - NCT05489068Recruiting
Motivational interviewing approach for people starting addiction treatment
This study compares two ways of having conversations when you begin outpatient addiction treatment. It tests whether a motivational interviewing style at intake improves your engagement and involvement in your care.
Albuquerque, New MexicoAges 18 years+ - NCT05509959Recruiting
Tech-based peer support for women with HIV and low adherence
This study tests a phone/computer-based peer support program to help women with HIV improve how consistently they take their HIV medicine (ART). It may help if you’ve had trouble meeting your medication schedule recently and you’re eligible to safely participate.
La Jolla, CaliforniaAges 18 years+ - NCT05519449RecruitingPhase 1
Testing a PSMA-targeting treatment for advanced prostate cancer
This Phase 1 trial tests JANX007 in men with metastatic castration-resistant prostate cancer (cancer that keeps growing despite standard hormone treatment). It aims to find a safe dose and see whether the treatment can shrink tumors or slow progression.
Birmingham, AlabamaAges 18–100 - NCT05534607Recruiting
Community hula program for dementia risk in older Native Hawaiians
This study tests whether joining a community hula (dance) program can help people reduce future dementia risk. It focuses on older Native Hawaiian or Pacific Islander adults who already have mild memory concerns and certain health conditions like high blood pressure or diabetes.
Honolulu, HawaiiAges 50–75 - NCT05555875Recruiting
Study how people engage with digital mental health tools
This study looks at what helps (or prevents) people from using digital mental health programs. You may join if you have meaningful depression and/or anxiety symptoms and you can use a smartphone for the study apps.
Boston, MassachusettsAges 18–75 - NCT05562557Recruiting
Fatherhood program to improve outcomes and support families
This study partners with fathers to help improve family outcomes, especially when there are worries about substance use in the household. You may be able to join if you are a father caregiver and your family has an identified risk for substance use, and you speak English or Spanish.
The Bronx, New YorkAges 18 years+ - NCT05591027RecruitingPhase 1
Testing Centella asiatica for memory problems in older adults
This Phase 1 study tests whether Centella asiatica (a plant-based supplement) is safe and reaches its intended target in people with mild cognitive impairment or early Alzheimer’s disease. It also checks how it affects memory-related brain measures like MRI scans, which is why multiple scans are required.
Portland, OregonAges 60–85 - NCT05595668Recruiting
Home computer therapy for brain neglect after stroke
This trial tests an at-home, phone/computer-based therapy to help people who have “neglect” after a stroke, using visual tasks to retrain attention. It may help improve how you notice and respond to the space on one side of your world.
Bedford, Nova ScotiaAges Any age - NCT05651295Recruiting
Smartphone precision study to improve emotion regulation
This trial tests a precision approach delivered through a smartphone to better track and target how you manage strong emotions. It may help if you have ongoing difficulty regulating emotions day to day.
Columbus, OhioAges 18 years+ - NCT05666986Recruiting
Sports and activity check-in for teens after diaphragmatic hernia surgery
This study looks at how adolescents who had diaphragmatic hernia surgery as babies engage in physical activities and sports. It will use questionnaires and an optional interview by video call to learn what helps or gets in the way—so care teams can better support families.
LilleAges 12–18
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Common questions
- Are there clinical trials for engagement?
- Yes. Clin2 currently lists 260 recruiting engagement studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a engagement trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a engagement trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.