Clinical trials
Esophageal Diseases clinical trials
Below are recruiting esophageal diseases clinical trials, each written for real people, not researchers. We’re tracking 56 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07131397Recruiting
Breathing muscle training for GERD
This trial tests whether strengthening your breathing muscles can help reduce GERD symptoms. You may be eligible if you have GERD and are in generally good health without other major conditions.
Athens, AtticaAges 18–70 - NCT05989698Recruiting
Validating a wearable cough monitor (C-mo)
This study tests a wearable device (C-mo) that monitors coughing. It is for people of all ages who are currently coughing and can cooperate with wearing a small sensor on their belly for a short time.
AlfenaAges 2 years+ - NCT07795645Recruiting
AI model training for stomach, heart, and brain diseases
This study is testing an artificial intelligence (AI) system that learns from your medical records to better understand and possibly help with diseases like stomach issues, heart problems, and strokes. It may improve how doctors use information from your visit to guide your care.
BeijingAges 18 years+ - NCT07163689Recruiting
TIPS for liver disease with portal hypertension
This trial compares patients who have a rare liver condition (porto-sinusoidal vascular disease) with those who have cirrhosis, to see how a procedure called TIPS (a shunt placed in the liver to reduce blood pressure) works for complications like bleeding, fluid buildup, or blood clots.
Amiens, PicardieAges 18 years+ - NCT05066594Recruiting
Registry for a procedure to treat long-term reflux
This is an observational study (no experimental treatment) that follows people who choose a specific procedure called transoral incisionless fundoplication (TIF) with the EsophyX device for long-term acid reflux. It aims to track outcomes for up to 5 years at San Raffaele Hospital.
MilanAges 18–80 - NCT07809620Recruiting
Acid reflux surgery: Who is likely to feel better?
This study looks at patients who are planning to have surgery for severe acid reflux (called fundoplication). It aims to find out which patients are most likely to see their symptoms improve after the operation, so doctors can better choose who will benefit.
Minya, Minya GovernorateAges 18 years+ - NCT07711912Enrolling by invitation
Polish AntiReflux Study (POLAR)
This study looks at how well acid reflux surgery works for people with GERD (chronic heartburn). If you're already scheduled for this surgery at a participating hospital, you may be able to join.
Olsztyn, Warminsko-mazusrkieAges 18 years+ - NCT07148492Recruiting
Stitch to prevent reflux after gastric bypass
This trial tests adding an antireflux stitch to a type of gastric bypass surgery to see if it helps reduce acid reflux. It may help patients who are already scheduled for this surgery.
Peshawar, KhyberpukhtunkhwaAges Any age - NCT04506593Recruiting
GI Motility diagnosis registry for people with digestion movement problems
This trial is a registry, meaning it collects information about people being evaluated for problems with how the gut moves. It may help doctors better diagnose gastrointestinal motility disorders in the future.
Indianapolis, IndianaAges Any age - NCT07121803Recruiting
Special ice cream for esophagus health in diabetes
This study tests whether a special ice cream can help the esophagus (the tube that carries food to your stomach) work better in people with type 2 diabetes. Researchers want to see if the ice cream can improve how food moves down the esophagus.
MoscowAges 18–80 - NCT06939465Recruiting
Cognitive therapy for throat and chest symptoms
This trial tests if a cognitive-behavioral therapy (a type of talk therapy that helps change thoughts and habits) can improve chronic throat and chest symptoms like heartburn, reflux, lump in throat, or trouble swallowing. It is for people who have these symptoms without a known structural problem in the esophagus.
Hualien CityAges 18–75 - NCT06778824Recruiting
Brain-gut medicine trial for chronic esophagus issues
This trial tests a type of brain-gut medicine to see if it helps with ongoing esophagus problems like heartburn, acid reflux, a lump in the throat, trouble swallowing, or chest pain. It might help if other treatments haven't worked well.
Hualien CityAges 18–75 - NCT07624383Recruiting
New topical treatment for nonerosive acid reflux disease
This study tests a new topical treatment for people with chronic heartburn and acid regurgitation who don't have erosions (damage) in their esophagus. The treatment is applied directly to the affected area and may help relieve symptoms without taking daily pills.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT06190782RecruitingPhase 3
Local therapy for limited metastatic esophageal cancer
This trial tests whether adding targeted radiation or other local treatments can help people with esophageal cancer that has spread to only a few spots (up to 4) after they've been treated with a PD-1 inhibitor. It aims to control the cancer better and improve outcomes.
ShanghaiAges 18 years+ - NCT07660627Recruiting
ctDNA test for tracking cancer after treatment
This trial uses a blood test to find tiny bits of tumor DNA after treatment. It helps doctors see if any cancer remains, which could guide next steps for people with esophageal, stomach, or pancreatic cancer.
BrnoAges Any age - NCT06926374Recruiting
Robotic surgery for gastrointestinal and urologic conditions
This trial tests a new robotic surgery system for common operations on the colon, rectum, prostate, kidney, bladder, stomach, esophagus, gallbladder, and hiatal hernia. It may offer a less invasive option for patients who need surgery for these conditions.
Hong KongAges 18–80 - NCT06668454Recruiting
Chemoimmunotherapy before surgery for limited spread esophageal cancer
This trial tests a treatment plan that combines chemotherapy with immunotherapy, followed by surgery, for people whose esophageal or stomach cancer has spread to a few areas (oligometastatic). The goal is to see if this approach can shrink the cancer and improve outcomes.
Toronto, OntarioAges 18–80 - NCT03853772Enrolling by invitation
Heartburn registry for long-term symptom and care follow-up
This registry enrolls people with GERD (chronic heartburn/reflux) to track symptoms and treatments over time for up to 5 years. It may help researchers understand what works best in everyday care, and you’ll be asked to complete check-in surveys.
Orange, CaliforniaAges 18 years+ - NCT07217704RecruitingPhase 3
New PET scan to find stomach or esophageal cancer spread
This trial tests a new PET scan drug (18F-FAPI) to see if it can better detect where stomach or esophageal cancer has spread. It may help doctors plan the right treatment for you.
Cerritos, CaliforniaAges 18 years+ - NCT06561178Recruiting
Blood Test to Monitor Esophageal Cancer After Surgery
This trial looks at whether a personalized blood test can detect cancer returning after surgery for esophageal cancer. It tests people who had chemoradiotherapy before surgery and still had some cancer remaining in the removed tissue. The goal is to use the blood test to catch any remaining or returning cancer early.
Guangzhou, GuangdongAges Any age - NCT05332639Recruiting
Risk tracking test for Crohn’s disease in teens
This study checks whether a personalized tool can estimate someone’s risk for Crohn’s disease before symptoms start. It may help families learn early risk and decide on next steps sooner.
Boston, MassachusettsAges 14 years+ - NCT02504853Recruiting
Study food allergy patterns and genetics over time
This study follows people with food allergy and some closely related or healthy people to learn how food allergy (and related conditions) develops over time. It may help researchers find causes and better ways to predict and treat food allergy.
Bethesda, MarylandAges 1 day–99 years - NCT07482969Recruiting
GERD symptoms in Czech children study
This study asks children ages 8-9 and 12-13 about symptoms of gastroesophageal reflux disease (GERD), a condition where stomach acid flows back into the throat. It aims to understand how common these symptoms are.
PragueAges 8–13 - NCT05199532Recruiting
Eosinophilic gut condition registry for children
This study builds a registry of children with eosinophilic gastrointestinal (gut) disorders (EGIDs) and also includes children being evaluated for possible EGIDs. It may help doctors better understand these conditions and improve future care.
Chicago, IllinoisAges 1–25
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Common questions
- Are there clinical trials for esophageal diseases?
- Yes. Clin2 currently lists 56 recruiting esophageal diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a esophageal diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a esophageal diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.