Clinical trials
Fertility clinical trials
Below are recruiting fertility clinical trials, each written for real people, not researchers. We’re tracking 171 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04298255Recruiting
Testicular injection therapy for certain causes of male infertility
This trial studies a special lab procedure where selected immature sperm cells are injected to help infertile couples achieve pregnancy. It is designed for couples where the man has a specific type of sperm-making problem found during a testicular sperm extraction.
Winston-Salem, North CarolinaAges 18 years+ - NCT07724405RecruitingPhase 2
G-CSF for Unexplained Recurrent Miscarriage During IVF
This study tests whether G-CSF (a medicine that helps the immune system) given during IVF can reduce miscarriages in women who have had repeated pregnancy losses with no clear reason.
Abu DhabiAges 18–44 - NCT07713797Recruiting
Biomarkers for endometriosis study
This study looks for biomarkers (biological signs) of endometriosis in women. It may help improve diagnosis and understanding of the condition.
Toronto, OntarioAges 18–45 - NCT02972801Recruiting
Freezing testicle tissue to protect future fertility
This study helps collect and freeze testicle tissue for people who must have surgery, chemotherapy, medicines, or radiation that could permanently harm fertility. You may join if you’re newly diagnosed or need planned treatment that threatens testicular function, and you agree to long-term follow-up.
Pittsburgh, PennsylvaniaAges Any age - NCT03011684RecruitingPhase 3
Preserve eggs using tamoxifen and letrozole during new breast cancer treatment
This study tests whether taking tamoxifen and letrozole (with fertility injections) can help people with newly diagnosed, estrogen-sensitive breast cancer preserve eggs before cancer treatment starts. It may help protect future fertility by collecting eggs early, before chemotherapy or other treatments begin.
San Francisco, CaliforniaAges 18–50 - NCT03463252RecruitingPhase 2/Phase 3
Hormone IUD to preserve fertility in early uterine cancer
This study looks at whether a hormone-releasing IUD (LNG-IUS) can treat early-stage endometrial cancer or very early abnormal cell growth while helping you keep the option for future pregnancy. It aims to see how well the treatment works and how it affects fertility-related outcomes.
Chengdu, SichuanAges Up to 40 years - NCT04008563Recruiting
Weight-loss surgery to protect fertility in early womb cancer
This study tests whether bariatric (weight-loss) surgery can help treat certain early, low-grade womb changes while preserving fertility. It’s mainly for people with a higher BMI who want to have children and have an early stage diagnosis confirmed by scans.
Toronto, OntarioAges 18–41 - NCT04016389Recruiting
Neoadjuvant chemo then fertility-sparing surgery for cervical cancer
This study looks at whether giving chemotherapy before surgery (neoadjuvant chemotherapy) can shrink certain cervical cancers enough to allow fertility-sparing surgery. It may help some people avoid removing the uterus, while still treating the cancer effectively.
Houston, TexasAges 18–40 - NCT04362046Recruiting
Fertility-friendly treatment for early uterine cancer or precancer
This trial studies whether removing an early, hormone-responsive uterine growth using a procedure through the cervix can keep fertility possible. It is for people under 40 with a specific low-risk uterine biopsy and MRI findings who have already tried hormone treatment.
Vancouver, British ColumbiaAges 19–39 - NCT04390308Recruiting
Testing gentle stimulation of ovaries before fertility treatment
This trial studies whether a “mechanical stimulation” procedure can help small egg-making structures in the ovary start to work again in people with primary ovarian insufficiency. If the procedure shows signs of response, you may then move on to further fertility treatment, including IVF.
Abu Dhabi, Abu Dhabi EmirateAges 18–40 - NCT04583150Recruiting
Study of fertility and ovarian reserve after weight-loss surgery
This study looks at how ovarian reserve (a fertility-related marker) changes in women after bariatric (weight-loss) surgery versus women with obesity who are not planning surgery. It may help doctors better understand fertility timing and risks around weight-loss treatment.
AngersAges 18–37 - NCT04682470Recruiting
Research study following young adults with cancer
This is an observational study that follows young adults with a confirmed cancer diagnosis to learn more about their experience and care. It does not test a new drug, but your information may help improve future cancer treatment and support.
Amsterdam, North HollandAges 18–39 - NCT04866329Recruiting
Study of stress and environmental exposures in IVF fertility
This study looks at how environmental exposures and stress-related “oxidant” changes may affect fertility outcomes in IVF for women. You may be invited if you are in your first IVF egg retrieval cycle and meet the study’s specific IVF setup rules.
ToursAges 18–43 - NCT04948658Recruiting
Freezing ovarian tissue to protect future fertility
This study looks at storing ovarian (ovary) tissue by freezing it for people at higher risk of losing fertility. It may help preserve options for having biological children later, especially for certain genetic conditions, cancer-related risks, or planned gonad removal.
Bethesda, MarylandAges 2–35 - NCT05239338Recruiting
Preserving fertility after colorectal cancer
This study looks at how to help people protect their ability to have children after colorectal cancer. It mainly includes younger adults who were diagnosed for the first time and can complete study questionnaires.
Nashville, TennesseeAges 18–49 - NCT05316493RecruitingPhase 2/Phase 3
Weight-loss and progesterone treatments for early uterine lining disease
This trial studies a weight-management approach plus a progesterone-releasing IUD (LNG-IUS) and megestrol to treat endometrial atypical hyperplasia, a high-risk precancer of the uterine lining. It may help shrink or control the abnormal cells while supporting fertility or keeping the uterus.
ShanghaiAges 18–45 - NCT05328258RecruitingPhase 3
Triptorelin to help protect fertility during cancer chemotherapy
This Phase 3 study tests whether a hormone medicine called triptorelin (a GnRH “fertility-protecting” medicine) can better protect ovarian function while you receive chemotherapy. The goal is to help preserve fertility and reduce the risk of early ovarian failure from cancer treatment.
GothenburgAges 14–42 - NCT05328999Recruiting
Study links fertility, pregnancy loss, and gut microbes
This trial studies how gut bacteria (your “microbiome”) may relate to infertility, recurrent pregnancy loss, and time to pregnancy. It may help researchers understand what could be changed to improve fertility outcomes.
Graz, StyriaAges 18–50 - NCT05443737RecruitingPhase 3
Telehealth care to protect fertility in young people with cancer
This trial tests a telehealth (video/phone) program that helps adolescents and young adults with cancer plan for future fertility. It may help you get support and options for preserving your ability to have children before cancer treatment affects it.
Duarte, CaliforniaAges birth–50 years - NCT05473273Recruiting
Blood test study during normal frozen embryo transfer
This study measures changes in your blood immune markers during frozen embryo transfer when the embryo is chromosomally normal. It may help clinics understand what blood immune patterns relate to successful pregnancy in natural or hormone-prepared cycles.
Abu Dhabi, Abu Dhabi EmirateAges 18–40 - NCT05616325Recruiting
Fertility follow-up for women after lymphoma chemotherapy
This study looks at long-term ovarian (egg-producing) fertility after chemotherapy for lymphoma, about 5 years after treatment ends. It may help doctors better understand pregnancy potential and guide future family-planning care.
LilleAges 18–45 - NCT05725512RecruitingPhase 4
Prednisolone to prevent unexplained recurrent miscarriages
This trial tests whether a medicine called prednisolone can help prevent further miscarriages in people who have had recurrent miscarriages with no known cause. If you qualify, you would take prednisolone early in pregnancy and the study team would watch whether more losses occur.
Leiden, South HollandAges 18–40 - NCT05740579Recruiting
Storing eggs in teens with Turner syndrome variants
This study looks at freezing and storing eggs (cryopreservation) in children and teens with Turner syndrome or related genetic variants. It may help preserve the chance of having biological children later, if you are able to undergo the study procedures safely.
AarhusAges 2–17 - NCT05837325Recruiting
Testing whether AMH levels predict embryo chromosome status
This study looks at whether a hormone level measured inside the fluid around eggs (follicular fluid) can predict whether embryos have the correct number of chromosomes. It may help clinics choose which embryos are more likely to be healthy.
Abu Dhabi, Abu Dhabi EmirateAges 18–40
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Common questions
- Are there clinical trials for fertility?
- Yes. Clin2 currently lists 171 recruiting fertility studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a fertility trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a fertility trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.