Clinical trials · Pennsylvania
GBM clinical trials in Pennsylvania
We’re tracking 7 recruiting gbm studies with a site in Pennsylvania — including Phase 1, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Pennsylvania
- NCT07326566RecruitingPhase 2
Silevertinib and chemo for a type of glioblastoma
This trial tests a new drug, silevertinib, combined with temozolomide (a chemotherapy) for people with a newly diagnosed glioblastoma that has certain genetic markers. It aims to see if this combination works better than standard treatment for tumors with these specific features.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05902169RecruitingPhase 3
Ultrasound with carboplatin for recurrent glioblastoma
This trial tests a device that opens the blood-brain barrier using ultrasound, allowing chemotherapy to reach the brain tumor better. It compares this approach to standard chemotherapy for people whose glioblastoma has returned.
Hershey, PennsylvaniaAges 18 years+ - NCT06805305RecruitingPhase 2
Immunotherapy for newly diagnosed glioblastoma
This trial tests a new personalized immunotherapy (DOC1021) for people with newly diagnosed glioblastoma. The treatment uses your own immune cells to attack the tumor and is given after surgery and with standard chemotherapy and radiation.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07195591RecruitingPhase 3
Starting radiation during brain cancer surgery vs. standard treatment
This trial tests putting radiation directly into the brain right after surgery for glioblastoma, instead of waiting for standard radiation later. It aims to see if this approach works better and is safe for you.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05086497Recruiting
Personal TTFields device guided by imaging for brain tumor
This trial tests whether using a personalized TTFields device—placed based on imaging—can help treat adults with glioblastoma (GBM) after surgery and radiation. It’s designed for specific GBM genetic types and may help deliver therapy more precisely.
Philadelphia, PennsylvaniaAges 22 years+ - NCT07225621RecruitingPhase 2
Light and sound therapy for newly diagnosed glioblastoma
This trial tests a new approach that uses a light-sensitive drug and low-intensity ultrasound to make standard chemotherapy more effective for glioblastoma. If you have completed initial treatment with radiation and temozolomide without the tumor growing, you may be eligible.
Hershey, PennsylvaniaAges 18–80 - NCT07209241RecruitingPhase 1
CAR-T cell therapy for recurrent glioblastoma
This study tests a new type of immunotherapy called CAR-T cells that are designed to attack two markers on your brain tumor cells (EGFR and IL13Ra2). The goal is to find the best way to give these cells after surgery and see if they can help control the tumor.
Philadelphia, PennsylvaniaAges 18 years+
Where these studies are running in Pennsylvania
Institutions with a site for the recruiting gbm studies listed above.
- Penn State Milton S Hershey Medical Center · 2 studies
- University of Pennsylvania · 2 studies
- Allegheny Health Network
- Thomas Jefferson University Hospital
- UPMC Hillman Cancer Center
- UPMC Presbyterian Hospital
What taking part in a gbm study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
GBM trials in other states
Common questions
- Are there gbm clinical trials in Pennsylvania?
- Yes. We're currently tracking 7 recruiting gbm studies with a site in Pennsylvania, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a gbm study in Pennsylvania?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Pennsylvania to take part?
- Not necessarily. These studies have a site in Pennsylvania, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a gbm trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New gbm studies open in Pennsylvania regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.