Clinical trials
Gut Microbiome clinical trials
Below are recruiting gut microbiome clinical trials, each written for real people, not researchers. We’re tracking 139 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07209007Recruiting
Skin and gut bacteria in healed burn wounds
This study looks at how burns change the bacteria on your skin and in your gut. It may help doctors understand healing better.
SeoulAges 19–65 - NCT05334888Recruiting
Study how sex and gut bacteria relate to heart risk
This study follows people over time to understand how sex-related factors and gut bacteria may affect heart and blood-vessel risk. It may help researchers identify who could benefit from earlier prevention, based on personal risk patterns.
BerlinAges 18–50 - NCT07388264Recruiting
Probiotic for bloating and gut health
This study tests a probiotic (a good bacteria) called Weizmannia coagulans to see if it helps reduce bloating and improves gut health. Researchers will check how your digestion changes by looking at your stool and gut bacteria.
Saint Charles, MissouriAges 18–50 - NCT07614542Recruiting
Understanding Gut Health and Hormones in Aging Women
This study explores how your gut bacteria and hormones change as you age. Researchers will collect stool and blood samples and ask about your health to better understand women's aging.
LisbonAges 40–64 - NCT05692024RecruitingPhase 1/Phase 2
Coffee and gut bacteria study after colon or rectal cancer
This early-phase study tests whether a coffee-related approach can change gut bacteria and blood “metabolites” after treatment for stage I–III colon or rectal cancer. The goal is to learn if these changes could help improve health after standard cancer treatment.
Boston, MassachusettsAges 18 years+ - NCT06588166Recruiting
Stool microbiome test for colon cancer screening
This study tests if a stool microbiome test can help find colorectal cancer early in people who already had a positive FIT screening test. You would give a stool sample and your microbiome results will be compared to what the colonoscopy finds.
RomaAges 50–74 - NCT07730229Recruiting
Plant-based drink study for healthy adults
This trial looks at how plant-based drinks affect the bacteria in your gut. You would drink a plant-based beverage daily and provide stool samples to see how your gut microbiome changes.
Lund, Skåne CountyAges 18–65 - NCT06837272Recruiting
Gut health and brain health in Alzheimer's disease
This study looks at how the bacteria in your gut might be connected to memory and thinking problems in Alzheimer's disease. It may help us understand if changes in the gut can affect brain health.
Jining, ShandongAges 60–80 - NCT05121025Recruiting
Study of stomach bacteria and gut microbes in Helicobacter infection
This study looks at how stomach bacteria (Helicobacter pylori) interact with the normal microbes in your gut. You may be asked to provide tissue, stool, and blood samples to help researchers understand infection and the body’s response.
Freiburg im Breisgau, Baden-WurttembergAges 18 years+ - NCT06607523Recruiting
Prebiotic treatment for brain injury recovery
This study tests whether a prebiotic (a type of fiber that feeds healthy gut bacteria) can improve recovery from a brain injury by helping the connection between the gut and the brain. Participants include people with a recent brain injury and their family members or staff, all of whom are part of the Moody Neurorehabilitation Institute community.
Galveston, TexasAges 18 years+ - NCT06800833Recruiting
Mango or cookie study for gut, mental, sexual, and skin health
This study is testing whether eating mangoes or low-fat cookies every day for 4 weeks can improve your gut health, and in turn affect your mood, sex life, and skin. If you are generally healthy, not pregnant, and not taking certain medications or supplements, you may be able to join.
San Diego, CaliforniaAges 18–50 - NCT07365514RecruitingPhase 1
Blackcurrants study for bone health in postmenopausal women
This trial tests if taking a blackcurrant supplement can help maintain bone density and reduce osteoporosis risk in postmenopausal women. You will take daily capsules and provide blood, stool, and bone scan samples over the study period.
Storrs, ConnecticutAges 45–70 - NCT06941090Recruiting
Stool sample collection for nutrition gut health study
This study asks participants of the NutriNet-Santé health study to provide a stool sample. Researchers want to understand how diet and gut bacteria affect health.
BobignyAges 18 years+ - NCT06738173Recruiting
Gut bacteria test to screen for colorectal cancer
This trial tests a new tool that looks at gut bacteria to help find colorectal cancer earlier. It's for people who already had a positive result on a standard stool test (FIT) as part of a national screening program.
Rome, RMAges 50–74 - NCT06741293Recruiting
Improving colorectal cancer early screening with stool tests
This study looks for markers in stool (poop) to detect colorectal cancer early. If you are between 40 and 74, live in the Lisbon area, and don't have certain digestive or cancer conditions, you may help improve screening by providing a stool sample.
Lisbon, Lisbon DistrictAges 40–74 - NCT05090267Recruiting
Gut-brain treatments for alcohol use and memory changes
This study tests whether gut-brain–targeted treatments (including probiotics and stimulation of a nerve) can improve thinking and inflammation-related health in people who use alcohol. You may be able to join if you have memory/thinking problems and meet specific medical limits, including HIV immune system levels.
Coral Gables, FloridaAges 35–70 - NCT07602920Recruiting
Understanding Gut Leakage in Dengue Fever
This study investigates whether dengue fever causes the intestinal lining to become leaky, allowing harmful substances to enter the bloodstream. Researchers compare blood markers in dengue patients and healthy volunteers to understand how this happens and why it might make dengue worse.
Chittagong, Chattogram DivisionAges 18 years+ - NCT03373721Recruiting
Compare gut microbes in preterm vs full-term babies
This study looks at differences in the gut bacteria of babies born early (preterm) compared with babies born full-term. It may help researchers understand how early birth affects early health and gut development.
ShanghaiAges 1 day–4 months - NCT06221800Recruiting
Gut bacteria and lung cancer treatment side effects study
This study looks at how the bacteria in your gut (microbiome) might affect how well your lung cancer treatment works and what side effects you experience. The goal is to learn if certain gut bacteria can predict treatment response or side effects for people with advanced non-small cell lung cancer.
Orange, CaliforniaAges 18 years+ - NCT07651462Recruiting
Fasting Before Hip Surgery and Gut Health
This study tests whether fasting for 20 days before hip replacement surgery changes your gut bacteria in ways that might help your recovery. Researchers want to understand if this dietary approach affects how well you heal after the operation.
Berlin, State of BerlinAges 18–75 - NCT07592975Recruiting
Food with Fiber and B-Vitamins for Gut Health in Older Adults
This study tests whether adding special fibers (prebiotics) and B-vitamins to food can improve your gut bacteria, reduce inflammation, and support mental health. You'll eat fortified foods for several weeks while researchers track changes in your digestion and wellbeing.
Coleraine, County LondonderryAges 50 years+ - NCT06749483Recruiting
Gut bacteria and infection in intensive care patients
This study looks at how gut bacteria affect severe infections in the ICU. It tests whether the microbiome can be a source of sepsis and a target for treatment. If you are critically ill or a long-term sepsis survivor, you might help find new ways to prevent infections.
Jena, ThuringiaAges 18 years+ - NCT06735599Recruiting
Wild blueberries for blood pressure health
This study tests whether eating wild blueberries can improve your gut, brain, and heart health if you have high blood pressure. You'll eat blueberries daily for several weeks and have checkups to see how your body responds.
Atlanta, GeorgiaAges 45–65 - NCT05774704RecruitingPhase 1/Phase 2
Curcumin eye study for people with retinal amyloid deposits
This early-stage study tests whether curcumin (a natural plant compound) can affect eye changes in people who have amyloid deposits in the retina. It aims to see if the treatment is safe and possibly helpful for vision-related outcomes.
Lubbock, TexasAges 40–89
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Common questions
- Are there clinical trials for gut microbiome?
- Yes. Clin2 currently lists 139 recruiting gut microbiome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gut microbiome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gut microbiome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.