Clinical trials
Gut Microbiome clinical trials
Below are recruiting gut microbiome clinical trials, each written for real people, not researchers. We’re tracking 141 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06749483Recruiting
Gut bacteria and infection in intensive care patients
This study looks at how gut bacteria affect severe infections in the ICU. It tests whether the microbiome can be a source of sepsis and a target for treatment. If you are critically ill or a long-term sepsis survivor, you might help find new ways to prevent infections.
Jena, ThuringiaAges 18 years+ - NCT06735599Recruiting
Wild blueberries for blood pressure health
This study tests whether eating wild blueberries can improve your gut, brain, and heart health if you have high blood pressure. You'll eat blueberries daily for several weeks and have checkups to see how your body responds.
Atlanta, GeorgiaAges 45–65 - NCT04775355Recruiting
Track urine and gut changes during prostate cancer treatment
This study looks at how your urine and gut (intestine) microbes change while you undergo prostate cancer treatments, including hormone therapy (androgen deprivation) and/or radiation. The goal is to better understand these biological changes, which may help improve future treatment planning.
Duarte, CaliforniaAges 18 years+ - NCT05037825Recruiting
Study gut microbes with immune therapy in several solid cancers
This trial looks at how the gut microbiome (the bacteria in your digestive system) relates to outcomes when you take standard immune “checkpoint” cancer medicines. If you’re eligible, they’ll collect stool samples while you receive treatment for certain cancers.
Elizabethtown, KentuckyAges 18 years+ - NCT03589183Recruiting
Gut microbiome study for ulcerative colitis and Crohn disease
This study looks at how changes in gut bacteria (the microbiome) relate to inflammatory bowel disease, including ulcerative colitis and Crohn disease. It may help researchers understand what might improve symptoms or disease control.
SeoulAges Any age - NCT05326334Recruiting
Study gut microbiome in new glioblastoma patients
This trial studies how changes in gut bacteria (gut microbiome) relate to outcomes in people with newly diagnosed glioblastoma receiving standard chemo-radiation. It may help doctors learn which gut-bacteria patterns go along with better or worse results during treatment.
Ottawa, OntarioAges 18 years+ - NCT05024188Recruiting
Gut bacteria and exercise performance study
This study looks at how the bacteria in your gut might affect your physical fitness and exercise ability. You would need to be a regular exerciser and take some antibiotics as part of the study.
RehovotAges 20–55 - NCT07868432Enrolling by invitation
How artificial sweeteners affect blood sugar in prediabetes
This study looks at how non-nutritive sweeteners (like aspartame or sucralose) affect blood sugar levels in people with prediabetes. It aims to see if these sweeteners change gut bacteria and, in turn, blood sugar control.
Boston, MassachusettsAges 35 years+ - NCT06260579Recruiting
Home exercise program after kidney transplant
This study tests whether a home exercise program, especially with higher intensity, can help people recover better after a kidney transplant. You would exercise on a stationary bike at home, with guidance from a team.
GhentAges 18 years+ - NCT04117321Recruiting
Study of mother-to-baby gut germs and baby health
This study looks at how germs in a mother can be passed to her baby and whether that affects the baby’s health. If you join, your baby (and the other parent or legal guardian) may be asked to share consent so researchers can follow the pregnancy and early life.
Hong Kong, Hong KongAges Any age - NCT06074250RecruitingPhase 2/Phase 3
Pregnancy, mood, and gut health study
This study tests whether a nutritional supplement can help prevent depression and anxiety during and after pregnancy. It looks at how the mother's gut bacteria may influence mood.
Toronto, OntarioAges 18–43 - NCT07750249Enrolling by invitationEarly Phase 1
Short-chain fatty acids for IgA nephropathy
This trial tests whether a daily supplement of short-chain fatty acids (SCFAs) can slow down kidney damage in people with IgA nephropathy. SCFAs are substances made by gut bacteria that may help reduce inflammation and protect the kidneys.
MartinAges 18 years+ - NCT05462496RecruitingPhase 2
Pembrolizumab plus gut microbiome changes after pancreatic chemo
This Phase 2 study tests whether changing the gut microbiome (the gut’s helpful bacteria) and giving pembrolizumab after chemotherapy can improve outcomes for people with operable pancreatic cancer. It aims to see if this approach can boost the immune system after standard treatment and help reduce cancer returning.
New York, New YorkAges 19 years+ - NCT06051318Recruiting
Diet and gut microbiome effects on blood sugar in healthy adults
This study looks at how your gut bacteria and the foods you eat affect your blood sugar after meals. You'll wear a small sensor to track your blood sugar for 10 days and provide stool samples.
Florianópolis, Santa CatarinaAges 18–60 - NCT07650149Recruiting
Study of genes, gut bacteria, and lifestyle in obesity
This study looks at how genes, gut bacteria, and lifestyle behaviors relate to weight. Researchers will test a weight-loss medication (tirzepatide) as part of the study to see if it helps people with overweight or obesity.
KrakowAges 18–65 - NCT07636850Recruiting
How almonds affect gut bacteria in children
This study looks at whether eating almonds changes the helpful bacteria in kids' stomachs and intestines. Researchers will give some children almonds to eat and study how it affects their digestive health.
Tallahassee, FloridaAges 6–13 - NCT06710574RecruitingPhase 4
Probiotics for sleep problems in Parkinson's disease
This study tests whether taking probiotics can improve REM sleep behavior disorder (RBD) in people with Parkinson's disease. You will receive either a probiotic supplement or a placebo, and researchers will use brain scans to see how it affects your symptoms.
BeijingAges 40–85 - NCT07585474Enrolling by invitation
Gut Health During Long Travel for Football Players
This study looks at how long airplane trips affect the gut bacteria in professional male football players. Researchers will track changes in your digestive system during pre-season travel to understand if travel impacts your gut health.
Nashville, TennesseeAges 18–40 - NCT03941080Recruiting
Study gut bacteria changes in advanced colorectal cancer
This study looks at how gut bacteria (the microbiome) change during treatment for colorectal cancer that has spread or cannot be removed. Researchers hope the findings may help improve understanding of how treatment works and how to tailor care.
AssenAges 18 years+ - NCT07517029Recruiting
Gut Bacteria Study in Post-Infectious IBS
This study looks at how gut bacteria may change in people who developed irritable bowel syndrome (IBS) after a stomach infection. Researchers hope to understand why some people recover completely while others develop ongoing digestive problems.
RomeAges 18 years+ - NCT07515430Enrolling by invitation
Gut Bacteria and Cancer Symptoms in Children With Leukemia
This study looks at how the bacteria living in your child's gut may affect cancer-related symptoms (like nausea, fatigue, or pain) during leukemia treatment. Researchers will collect stool samples and track symptoms to understand this connection better.
Guangzhou, GuangdongAges 5–18 - NCT06171360Recruiting
Gut bacteria and CDK4/6 inhibitor treatment in breast cancer
This study looks at how gut bacteria affect response to a type of targeted therapy (CDK4/6 inhibitors) combined with hormone therapy in breast cancer that is hormone receptor-positive and HER2-negative. It may help find out why some people respond better to treatment and could lead to better personalized care.
BrusselsAges 18–100 - NCT07477470Recruiting
Fiber supplement for stress and mood
This study tests whether a daily fiber supplement can improve mood, memory, and gut health in stressed adults. It lasts a few weeks and involves questionnaires and samples.
LondonAges 18–50 - NCT07457723RecruitingPhase 2
Gut health and metabolism study
This study tests whether a supplement can improve metabolic health by changing the bacteria in your gut. It looks at how your body processes food and energy.
Brisbane, QueenslandAges 18 years+
Hear when a new Gut Microbiome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for gut microbiome?
- Yes. Clin2 currently lists 141 recruiting gut microbiome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gut microbiome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gut microbiome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.