Clinical trials
Gut Microbiome clinical trials
Below are recruiting gut microbiome clinical trials, each written for real people, not researchers. We’re tracking 139 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06433115Recruiting
Lean beef and your heart and gut health trial
This study tests how eating lean beef for 4 weeks affects your heart health and the bacteria in your gut. If you qualify, you'll be asked to follow a consistent diet and activity routine during the study.
Columbia, MissouriAges 18–45 - NCT07750249Enrolling by invitationEarly Phase 1
Short-chain fatty acids for IgA nephropathy
This trial tests whether a daily supplement of short-chain fatty acids (SCFAs) can slow down kidney damage in people with IgA nephropathy. SCFAs are substances made by gut bacteria that may help reduce inflammation and protect the kidneys.
MartinAges 18 years+ - NCT05417867Recruiting
Tracking gut bacteria changes and nausea during chemo
This study looks at how changes in the gut “microbiome” (your gut bacteria) relate to fatigue and chemotherapy-induced nausea in people with early-stage breast cancer. It may help doctors better understand why nausea and fatigue happen and how to predict or manage them during treatment.
Scottsdale, ArizonaAges 20 years+ - NCT04117321Recruiting
Study of mother-to-baby gut germs and baby health
This study looks at how germs in a mother can be passed to her baby and whether that affects the baby’s health. If you join, your baby (and the other parent or legal guardian) may be asked to share consent so researchers can follow the pregnancy and early life.
Hong Kong, Hong KongAges Any age - NCT05598112RecruitingEarly Phase 1
Oral stool-based microbiome treatment for healthy aging
This early-stage study tests whether changing the gut bacteria using an oral stool-based treatment (called oral FMT) can improve health in older adults. It aims to see if this approach affects aging-related changes, including gut and body function.
Beijing, Beijing MunicipalityAges 70–85 - NCT06252948Recruiting
Gut bacteria study for POEMS and related plasma cell disorders
This study looks at the gut microbiome (the bacteria living in your digestive system) in people with POEMS syndrome, multiple myeloma, MGUS, amyloidosis, and healthy household members. It may help researchers understand how gut health relates to these conditions.
Rochester, MinnesotaAges 18 years+ - NCT07052409Enrolling by invitation
Protecting HIV-exposed infants from severe infections
This trial studies ways to protect babies who were exposed to HIV before birth but are not infected themselves. It aims to find better interventions to prevent severe infections in these infants.
JohannesburgAges 6 months–45 years - NCT07082348Recruiting
Herbs and spices for better diet in college students
This study tests whether adding herbs and spices to your daily meals can help improve your diet quality over a short period. It is designed for college students who feel their eating habits could be healthier.
Las Vegas, NevadaAges 18–39 - NCT06833593Recruiting
Antibiotic combinations for enterococcus blood infection
This study looks at whether using two or more antibiotics together works better than one alone for a specific type of blood infection caused by Enterococcus faecalis bacteria. The goal is to find the safest and most effective way to treat this infection and improve outcomes for patients.
Bologna, BolognaAges 18 years+ - NCT07200531Recruiting
Can therapy change gut bacteria in women?
This trial studies whether psychotherapy can affect the bacteria living in your gut. It is for women aged 19 to 53 who are not pregnant, breastfeeding, or already in regular therapy.
Omaha, NebraskaAges 19–54 - NCT07585474Enrolling by invitation
Gut Health During Long Travel for Football Players
This study looks at how long airplane trips affect the gut bacteria in professional male football players. Researchers will track changes in your digestive system during pre-season travel to understand if travel impacts your gut health.
Nashville, TennesseeAges 18–40 - NCT06260579Recruiting
Home exercise program after kidney transplant
This study tests whether a home exercise program, especially with higher intensity, can help people recover better after a kidney transplant. You would exercise on a stationary bike at home, with guidance from a team.
GhentAges 18 years+ - NCT05135351Recruiting
Prebiotics to help your gut health after cancer cell treatment
This trial tests whether taking prebiotics (food for helpful gut bacteria) can improve gut microbiome diversity after your own cancer-cell treatment, like autologous stem cell transplant or CAR-T. It may help your gut ecosystem recover during and after therapy.
Omaha, NebraskaAges 19 years+ - NCT07457723RecruitingPhase 2
Gut health and metabolism study
This study tests whether a supplement can improve metabolic health by changing the bacteria in your gut. It looks at how your body processes food and energy.
Brisbane, QueenslandAges 18 years+ - NCT03325855Recruiting
Fecal transplant registry for patients and donors
This study is a national “registry” that collects information from people who get fecal microbiota transplant (a stool-based treatment) and from people who donate stool. It helps researchers understand who receives these treatments and how they do over time.
Phoenix, ArizonaAges Any age - NCT03589183Recruiting
Gut microbiome study for ulcerative colitis and Crohn disease
This study looks at how changes in gut bacteria (the microbiome) relate to inflammatory bowel disease, including ulcerative colitis and Crohn disease. It may help researchers understand what might improve symptoms or disease control.
SeoulAges Any age - NCT03612193Recruiting
Study how gut bacteria relates to complex regional pain
This study looks at differences in gut bacteria (from a stool sample) in people with complex regional pain syndrome (CRPS) and in people who live with them. The goal is to understand whether gut microbes might play a role in CRPS and improve understanding of the condition.
St Louis, MissouriAges 18 years+ - NCT03819296RecruitingPhase 1
Fecal transplant to treat cancer immunotherapy bowel side effects
This early-phase study tests whether changing your gut bacteria with a fecal transplant can improve diarrhea or colitis caused by cancer immunotherapy. It may help people whose symptoms have not fully settled with standard treatments like steroids and other immune-blocking medicines.
Houston, TexasAges 18 years+ - NCT03941080Recruiting
Study gut bacteria changes in advanced colorectal cancer
This study looks at how gut bacteria (the microbiome) change during treatment for colorectal cancer that has spread or cannot be removed. Researchers hope the findings may help improve understanding of how treatment works and how to tailor care.
AssenAges 18 years+ - NCT04590690Recruiting
Gut microbes and sex risks for kidney stones after weight surgery
This study looks at how gut bacteria (microbes), along with sex, may affect the chance of getting kidney stones after bariatric (weight-loss) surgery. It may help doctors understand who is at higher risk so prevention can be improved.
Chicago, IllinoisAges 18–130 - NCT04775355Recruiting
Track urine and gut changes during prostate cancer treatment
This study looks at how your urine and gut (intestine) microbes change while you undergo prostate cancer treatments, including hormone therapy (androgen deprivation) and/or radiation. The goal is to better understand these biological changes, which may help improve future treatment planning.
Duarte, CaliforniaAges 18 years+ - NCT05037825Recruiting
Study gut microbes with immune therapy in several solid cancers
This trial looks at how the gut microbiome (the bacteria in your digestive system) relates to outcomes when you take standard immune “checkpoint” cancer medicines. If you’re eligible, they’ll collect stool samples while you receive treatment for certain cancers.
Elizabethtown, KentuckyAges 18 years+ - NCT05112614Recruiting
Study links gut bacteria to cancer treatment response
This study looks at how the bacteria in your gut change during cancer treatment (and during some blood stem cell transplants). It may help researchers understand why some people respond differently and guide better future treatment.
Scottsdale, ArizonaAges 18–99 - NCT05326334Recruiting
Study gut microbiome in new glioblastoma patients
This trial studies how changes in gut bacteria (gut microbiome) relate to outcomes in people with newly diagnosed glioblastoma receiving standard chemo-radiation. It may help doctors learn which gut-bacteria patterns go along with better or worse results during treatment.
Ottawa, OntarioAges 18 years+
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Common questions
- Are there clinical trials for gut microbiome?
- Yes. Clin2 currently lists 139 recruiting gut microbiome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gut microbiome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gut microbiome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.