Clinical trials
Gastrointestinal Microbiome clinical trials
Below are recruiting gastrointestinal microbiome clinical trials, each written for real people, not researchers. We’re tracking 21 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06207136Recruiting
Diet and Gut Bacteria in Parkinson's
This study looks at how diet and the bacteria in your gut (microbiome) affect Parkinson's symptoms. You'll work with a coach and take cooking classes to see if changing what you eat can help you feel better.
Vancouver, British ColumbiaAges 40–80 - NCT04359836Recruiting
Study of gut bacteria in early COVID-19
This trial studies how gut bacteria (“gut flora”) may affect COVID-19 after a recent infection. If you test positive for COVID-19 soon enough, the study may help researchers understand why some people get better faster or have different symptoms.
Ventura, CaliforniaAges 18 years+ - NCT07453823Recruiting
Synbiotic for gut health in overweight adults
This trial tests a combination supplement (a synbiotic) to see if it can improve gut function and gut bacteria in middle-aged and older adults who are overweight and have constipation. If eligible, you take the supplement daily and report how your digestion feels.
Cork, BlackpoolAges 50–70 - NCT07264998Recruiting
Gut bacteria study in breast cancer patients on Abemaciclib
This study looks at how gut bacteria changes in people taking Abemaciclib (a breast cancer drug) and whether that relates to diarrhea. It may help find ways to prevent or manage this side effect.
Wuhan, HubeiAges 18–75 - NCT03298334RecruitingPhase 1/Phase 2
Testing vaginal bacteria transfer to newborns after C-section
This study looks at whether they can safely place “healthy vaginal bacteria” from the mother into the newborn after a scheduled C-section, and whether it improves the baby’s health. It only enrolls certain mothers and babies based on infection testing and other health factors.
Falls Church, VirginiaAges birth–50 years - NCT05692024RecruitingPhase 1/Phase 2
Coffee and gut bacteria study after colon or rectal cancer
This early-phase study tests whether a coffee-related approach can change gut bacteria and blood “metabolites” after treatment for stage I–III colon or rectal cancer. The goal is to learn if these changes could help improve health after standard cancer treatment.
Boston, MassachusettsAges 18 years+ - NCT07730229Recruiting
Plant-based drink study for healthy adults
This trial looks at how plant-based drinks affect the bacteria in your gut. You would drink a plant-based beverage daily and provide stool samples to see how your gut microbiome changes.
Lund, Skåne CountyAges 18–65 - NCT07388264Recruiting
Probiotic for bloating and gut health
This study tests a probiotic (a good bacteria) called Weizmannia coagulans to see if it helps reduce bloating and improves gut health. Researchers will check how your digestion changes by looking at your stool and gut bacteria.
Saint Charles, MissouriAges 18–50 - NCT07651462Recruiting
Fasting Before Hip Surgery and Gut Health
This study tests whether fasting for 20 days before hip replacement surgery changes your gut bacteria in ways that might help your recovery. Researchers want to understand if this dietary approach affects how well you heal after the operation.
Berlin, State of BerlinAges 18–75 - NCT07735182Recruiting
Gut bacteria and organ damage in sepsis
This study looks at how bacteria in your gut and other signs in your body affect liver and kidney damage in people with sepsis. It also compares findings to healthy volunteers to see what is different.
Hangzhou, ZhejiangAges 18 years+ - NCT07724522Recruiting
Prebiotic Fiber for Irregular Periods in Women
This study tests whether taking a prebiotic fiber (inulin) can help women who are in the later years of their reproductive life (before menopause) and have irregular periods. You may be eligible if you are overweight, have irregular cycles, sit a lot, and do not exercise much.
Washington D.C., District of ColumbiaAges 40–55 - NCT06205862RecruitingPhase 2
Fecal transplant for preventing colon polyp return
This study tests whether taking capsules of healthy bacteria (fecal microbiota transplant) can help prevent colon polyps from coming back after they have been removed. It might be an option for people who have had an adenoma polyp removed and want to reduce the chance of recurrence.
Guangzhou, GuangdongAges 18–75 - NCT07437911Recruiting
Can a Supplement Help with Nutrient Gaps for GLP-1 Users?
This study tests whether a daily supplement can help fill nutrient gaps and improve gut health for people who are already taking GLP-1 weight-loss medications (like Ozempic or Wegovy). Participants must be on a stable dose for at least 8 weeks and be generally healthy without other chronic conditions.
Santa Monica, CaliforniaAges 18–59 - NCT06802276Recruiting
Smart underwear measures gas from diet
This study tests special underwear that can measure gas produced by digestion after eating different foods. Researchers want to see if the underwear can track how diet affects gas production.
Aurora, ColoradoAges 18 years+ - NCT05307367Recruiting
Study exercise and body muscle changes in advanced lung cancer
This study looks at why cancer can cause loss of muscle in people with advanced non–small cell lung cancer, and whether exercise can improve or explain those muscle changes. You may be asked to do physical testing and answer questionnaires while receiving standard palliative cancer treatment.
Copenhagen, DKAges 18–100 - NCT05878977Recruiting
Testing biomarkers in immunotherapy for advanced melanoma
This trial looks at tissue and scan-related markers (“biomarkers”) to better understand how immunotherapy works in people with advanced melanoma. You may receive standard first-line immunotherapy, and your recent scans and health details will help researchers study why some people respond better than others.
LjubljanaAges 18 years+ - NCT06359808Recruiting
Sleep Problems in Ulcerative Colitis Patients
This study looks at sleep problems in people with ulcerative colitis (a type of inflammatory bowel disease). It aims to understand how sleep affects your condition and may help find better ways to manage both.
Xi'an, ShaanxiAges 18–65 - NCT07424469Recruiting
Leaks in the esophagus or stomach: microbiome role
This study looks at the role of tiny organisms (the microbiome) in leaks from the esophagus or stomach. Researchers will take small tissue samples to learn more about these leaks and how to treat them better.
Dallas, TexasAges 18 years+ - NCT06072976Recruiting
How feeding affects gut health in babies with bowel conditions
This study looks at whether breast milk or formula helps babies with certain bowel problems heal faster and reach full feeds sooner. It compares how different milk affects the bacteria in a baby's gut.
Seattle, WashingtonAges birth–55 years - NCT07402226Recruiting
Diet study for bloating with scleroderma
This study tests whether a special diet can help reduce bloating and stomach discomfort in people with scleroderma (systemic sclerosis). You'll follow a specific meal plan to see if it improves your digestive symptoms.
Ann Arbor, MichiganAges 18 years+ - NCT06639126Enrolling by invitation
Thyme extract for functional gut issues
This trial tests whether a wild thyme extract can help with functional gastrointestinal disorders (common digestive problems without a clear cause). It focuses on the extract's anti-inflammatory and metabolism-related effects.
Granada, GranadaAges 18–75
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Common questions
- Are there clinical trials for gastrointestinal microbiome?
- Yes. Clin2 currently lists 21 recruiting gastrointestinal microbiome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gastrointestinal microbiome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gastrointestinal microbiome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.