Clinical trials · California
Hepatic Impairment clinical trials in California
We’re tracking 9 recruiting hepatic impairment studies with a site in California — including Phase 1 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT07643155RecruitingPhase 1
Safety study of inhaled treprostinil in people with liver disease
This early-stage study tests how the body processes a new inhaled breathing medication (treprostinil) and whether it's safe in people with normal liver function and those with chronic liver disease. The goal is to understand if the medication works differently depending on liver health.
Lake Forest, CaliforniaAges 18–70 - NCT07343960RecruitingPhase 1
Study of Capivasertib in people with moderate liver impairment
This trial tests how the drug capivasertib is processed by the body and how safe it is in people with moderate liver impairment. It aims to find the right dose for patients whose liver function is reduced but stable.
Rialto, CaliforniaAges 18–80 - NCT07546760RecruitingPhase 1
Study of how liver disease affects two new medications
This research study tests how two experimental drugs (AZD9550 and AZD6234) work in people with different levels of liver function. The goal is to understand whether liver disease changes how the body processes these medications, which may help doctors safely treat patients with liver problems in the future.
Rialto, CaliforniaAges 18–85 - NCT07144111RecruitingPhase 1
Liver Function and Inavolisib Study
This study tests how the body processes the drug inavolisib when taken by people with moderate or severe liver problems compared to those with healthy livers. It helps doctors understand the right dose for patients with liver impairment.
Lake Forest, CaliforniaAges 18–80 - NCT05484206RecruitingPhase 1
Study how liver impairment affects two investigational medicines
This Phase 1 study tests how two investigational medicines move through the body and how safe they are in people with different levels of liver impairment, compared with healthy volunteers. It may help doctors understand dosing and safety for people with liver problems.
Rialto, CaliforniaAges 18–70 - NCT07036133RecruitingPhase 1
Study of Pralatrexate in patients with advanced cancer and liver problems
This trial tests a drug called pralatrexate in people with advanced solid tumors or blood cancers, including those with different levels of liver function. The goal is to understand how the drug works in the body and how safe it is for patients with various degrees of liver impairment.
Cerritos, CaliforniaAges 18 years+ - NCT07023354RecruitingPhase 1
Study of BI 1291583 in people with and without liver problems
This trial tests how a new medicine, BI 1291583, enters the blood in people who have different levels of liver function (from normal to mild, moderate, or severe liver problems). It helps doctors understand if the dose needs to be adjusted for liver health.
Rialto, CaliforniaAges 18–80 - NCT07269301RecruitingPhase 1
Liver function and study drug processing
This study looks at how the medicine PF-07328948 is processed by people with different levels of liver function. It includes both healthy people and those with stable liver disease (classified as mild, moderate, or severe). The goal is to see if the liver condition affects how the drug works in the body.
Lake Forest, CaliforniaAges 18–74 - NCT07358546RecruitingPhase 1
Test of efimosfermin alfa in adults with liver problems
This trial is for adults with liver cirrhosis (scarring) who have moderate to severe liver impairment. It studies how the body handles a new medicine called efimosfermin alfa, to see if it could be a safe treatment option. You may be able to join if your liver function is stable and you fall into a specific Child-Pugh class.
Rialto, CaliforniaAges 18–70
Hepatic Impairment trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting hepatic impairment studies listed above.
- Orange County Research Center · 3 studies
- Inland Empire Clinical Trials · 2 studies
- Research Site · 2 studies
- GSK Investigational Site
- Orlando County Research Center
- TOI Clinical Research
What taking part in a hepatic impairment study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Hepatic Impairment trials in other states
Common questions
- Are there hepatic impairment clinical trials in California?
- Yes. We're currently tracking 9 recruiting hepatic impairment studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a hepatic impairment study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a hepatic impairment trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New hepatic impairment studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.