Clinical trials
HIV Prevention clinical trials
Below are recruiting hiv prevention clinical trials, each written for real people, not researchers. We’re tracking 102 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05165745Recruiting
Study of PrEP choices in women and transgender people
This study asks people who may use PrEP—an HIV prevention medicine—about their decision to start, not start, or stop PrEP. It aims to understand needs and barriers so PrEP can work better for cisgender women and transgender people who are considering it.
New York, New YorkAges 18 years+ - NCT06485154RecruitingPhase 4
Finding the best HIV treatment after PrEP shot failure
This trial is for people who got exposed to HIV despite taking the long-acting PrEP shot (cabotegravir). It tests different pill-based HIV treatment plans to find the best option for them.
Johannesburg, GautengAges 15 years+ - NCT06158126RecruitingPhase 4
Pregnancy and infant health outcomes study
This study follows pregnant women and their babies to see how well HIV prevention medicines work during pregnancy. It aims to help keep both mother and baby healthy.
LilongweAges 15–55 - NCT05968755Recruiting
Chatbot to help black men in the south start PrEP
This study tests a chatbot that gives you information and support to help you start or stay on PrEP, a daily pill that prevents HIV. It's for Black men in the Southern U.S. who might be at higher risk.
Miami, FloridaAges 18 years+ - NCT05804461Recruiting
PrEP support study for Latino gay and bisexual men in Puerto Rico
This study tests ways to help Latino men who have sex with men use PrEP, a medicine that helps prevent HIV. You may be invited if you are HIV-negative (or your status is unknown), are not currently on PrEP, and can read and write Spanish.
San JuanAges 21–99 - NCT05769023Enrolling by invitation
Pilot test targeting HIV prevention for people who inject drugs
This pilot program studies where HIV risk is highest and uses that information to decide how prevention efforts should be delivered. If you’ve used opioids recently and you inject drugs, you may be invited to participate to help reduce HIV risk.
Baltimore, MarylandAges 18 years+ - NCT02437981Enrolling by invitation
PrEP for HIV prevention in high-risk adults in Thailand
This trial checks how well PrEP pills (TDF/FTC) prevent HIV in people who are at high risk and are HIV-negative. It may help you understand whether PrEP is a good prevention option for your situation.
Bangkok, PathumwanAges 18 years+ - NCT07223398Recruiting
Making HIV care decisions with people who've been in the justice system
This trial helps people recently involved with the justice system and who use stimulants or opioids decide on HIV prevention or treatment. It tests a shared decision-making approach for taking HIV medication (ART) or PrEP.
New Haven, ConnecticutAges 18 years+ - NCT06568484RecruitingPhase 2/Phase 3
Preventing TB with bedaquiline in people exposed to TB
This study tests if bedaquiline can prevent tuberculosis (TB) in people who have been in close contact with someone with active TB, including people living with HIV. If you qualify, you would take the study medicine and be monitored to see if it prevents you from developing TB.
UlaanbaatarAges Any age - NCT06281834RecruitingPhase 1
Dolutegravir levels with TB prevention in children
This study tests how dolutegravir (an HIV medicine) works in children when taken with weekly rifapentine and isoniazid (medicines to prevent tuberculosis). It may help find the right dose for kids who have HIV and are at risk for TB.
Ibadan, Oyo StateAges 4 weeks–11 years - NCT06842732Recruiting
Text messages to prevent wasting in HIV-affected children in Kenya
This trial tests if two-way text messages (SMS) can help caregivers recognize early signs of malnutrition (wasting) in children who have HIV or were exposed to HIV but are uninfected. The goal is to prevent wasting and keep children healthy.
Homa BayAges 6 months–2 years - NCT06883097Recruiting
Quitting smoking with HIV: A smoking cessation trial
This study tests whether nicotine replacement therapy (like patches or gum) can help people living with HIV quit smoking. You'll be part of a program that supports your quit attempt while you receive care for HIV.
Winston-Salem, North CarolinaAges 18 years+ - NCT06501781Recruiting
PUSH: Helping People with HIV and Substance Use
This study tests if a program that encourages positive activities (behavioral activation) can help people with HIV or on PrEP who also use substances improve their health. It focuses on those receiving long-acting injectable medications for HIV prevention or treatment.
Washington D.C., District of ColumbiaAges 18–88 - NCT05352061Enrolling by invitation
HIV support program for people with mental health and life challenges
This study looks at how an HIV treatment and prevention program can be improved for people who have HIV plus psychosocial challenges, especially when HIV is not well controlled. You may be able to join if your HIV is recent and higher than target, and you fit one of the specific participant groups.
Miami, FloridaAges 18 years+ - NCT07270406Recruiting
Healthy habits for better sleep in people with HIV and pain
This study tests a healthy behaviors program to help prevent insomnia in people with HIV who also have ongoing pain. If you have trouble sleeping and chronic pain, this program may help improve your sleep and well-being.
St Louis, MissouriAges 25–65 - NCT07221214RecruitingPhase 2
Testing a diabetes drug for drinking and heart health in HIV
This trial tests if a once-weekly diabetes medication (semaglutide) can help people with HIV reduce heavy drinking and improve heart health. It's for people who drink alcohol and have a higher body weight.
Nashville, TennesseeAges 18–89 - NCT06771843Recruiting
Helping men with HIV reduce drinking and improve HIV prevention
This study tests whether helping men with HIV who also drink heavily can lower their alcohol use and improve how well HIV treatment works to prevent passing the virus to others. It's for men living in fishing communities in Uganda.
KampalaAges 18 years+ - NCT07706634Recruiting
Helping people with HIV stay in care
This study tests ways to help people living with HIV in Indonesia stay engaged in their care. It may help you if you want extra support to keep up with your appointments and treatment.
Depok, West JavaAges 18 years+ - NCT07541131Enrolling by invitation
Reducing HIV stigma to improve treatment access for drug users
This study tests whether reducing stigma and discrimination against people who use drugs can help more people access HIV treatment and prevention. You would participate in peer-led group sessions and surveys over 18 months to help researchers understand how stigma affects treatment access in Bishkek.
BishkekAges 18 years+ - NCT05463692Enrolling by invitation
Study of STI prevention and sexual health in Alabama women
This study follows women in Alabama to better understand sexual health and STI prevention over time. You may be able to join if you recently had an STI report and you’re currently negative for HIV, gonorrhea, and syphilis.
Birmingham, AlabamaAges 18–89 - NCT07071623RecruitingPhase 3
A study of an experimental drug to prevent HIV
This trial tests a new medication called MK-8527 to see if it can prevent HIV-1 infection in women who are at risk. If you are a cisgender woman, HIV-negative, and sexually active, this study could be an option for you.
Homabay County, Homa Bay CountyAges 16–30 - NCT07209917Recruiting
Cervical cancer prevention for women with HIV and HPV
This trial tests a new way to prevent cervical cancer in women with both HIV and HPV. It focuses on women in India who are already on stable HIV treatment and have a normal cervical exam.
Bangalore, KarnatakaAges 25–50 - NCT06800664Recruiting
Home self-sampling for cervical cancer prevention in Ghana
This study tests at-home self-sampling kits to help prevent cervical cancer in women living with HIV in Ghana. Participation is completely voluntary, involves collecting your own sample at home, and aims to make screening easier.
Cape Coast, Central RegionAges 25–65 - NCT07486661Recruiting
Preventing frailty in people with HIV aged 65-75
This study aims to help people with HIV between the ages of 65 and 75 stay healthy and avoid becoming frail as they age. It tests a program to prevent frailty and see if it works.
BrusselsAges 65–74
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Common questions
- Are there clinical trials for hiv prevention?
- Yes. Clin2 currently lists 102 recruiting hiv prevention studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hiv prevention trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hiv prevention trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.