Clinical trials
Hot Flashes clinical trials
Below are recruiting hot flashes clinical trials, each written for real people, not researchers. We’re tracking 24 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06957691RecruitingPhase 2
Fezolinetant for hot flashes in men on hormone therapy
This study tests a medication called fezolinetant to see if it reduces hot flashes in men undergoing hormone therapy for prostate cancer. If you experience frequent hot flashes, this treatment might help alleviate them.
Boston, MassachusettsAges 40 years+ - NCT07238478Recruiting
Supplement for menopause quality of life in postmenopausal women
This trial tests a dietary supplement to see if it can improve menopause-related symptoms, like hot flashes and joint discomfort, in healthy postmenopausal women.
Harrison, New YorkAges 50–70 - NCT06499311Recruiting
Foot massage vs acupressure for hot flashes and sleep
This study compares two gentle foot therapies—reflexology and acupressure—to see which one helps more with hot flashes and sleep problems in women going through menopause.
GizaAges 45–55 - NCT07335224Recruiting
Acupuncture for hot flashes in men with prostate cancer
This trial tests if acupuncture can reduce the daily discomfort from hot flashes caused by hormone therapy (androgen deprivation therapy) for prostate cancer. It may help men who are bothered by frequent or intense hot flashes find better relief.
Fairfax, VirginiaAges 18 years+ - NCT01530373RecruitingPhase 2
Solifenacin vs clonidine to reduce breast cancer hot flashes
This trial compares two medicines—solifenacin and clonidine—to see which one better reduces hot flashes in people taking hormone-blocking cancer medicines. If you have frequent hot flashes, joining could help researchers find an effective option for symptom relief.
Little Rock, ArkansasAges 18 years+ - NCT05251324Recruiting
Study effects of hot flushes on heart and blood pressure
This study looks at how hot flushes (also called hot flashes) may affect heart function and blood pressure in postmenopausal people. You may be able to take part if you are not currently using hormone therapy or can stop it for the study.
Minneapolis, MinnesotaAges 40–70 - NCT05193968Recruiting
Study hot flashes and blood vessel function in women
This study looks at how hot flashes relate to how well your blood vessels work in the body. It may help researchers understand the body changes behind hot flashes, which could guide future treatments.
Rochester, MinnesotaAges 40–60 - NCT07602530Recruiting
Tracking Hot Flash Treatment Outcomes in Canadian Women
This study follows women in Canada who are starting fezolinetant, a new medication for hot flashes during menopause. Researchers will track how well it works and how you feel while using it in your regular doctor's care.
MontrealAges Any age - NCT07077395RecruitingPhase 2
Hot flash study to check heart health links
This study looks at how hot flashes in midlife women might be connected to heart disease risk. Researchers want to see if managing hot flashes can improve heart health.
Boston, MassachusettsAges 40–65 - NCT06106529RecruitingPhase 3
Reducing hot flashes in women on hormone therapy for breast cancer
This trial tests a new approach to reduce hot flashes in women taking hormone therapy for breast cancer. You may be able to join if you have at least 14 hot flashes a week and are not taking certain other treatments.
Delft, South HollandAges 18 years+ - NCT07594002Recruiting
Acupuncture for hot flashes in prostate cancer patients
This study tests whether real acupuncture works better than fake acupuncture for reducing hot flashes (sudden episodes of intense heat and sweating) in men with prostate cancer who are on hormone therapy. If acupuncture helps, it could offer relief without more medications.
Lexington, KentuckyAges 18–99 - NCT06487130Recruiting
Australia menopause registry study
This study is building a registry to better understand and support Australians going through perimenopause or menopause. By joining, you help researchers learn about the experiences and needs of people in this stage of life.
AdelaideAges 18 years+ - NCT06030388Recruiting
Exercise study for hot flash relief in menopause
This study tests whether strength training or high-intensity aerobic exercise can reduce hot flashes in postmenopausal women. You would exercise 3 times a week for 15 weeks to see if it helps your symptoms.
KalmarAges 45 years+ - NCT07218445RecruitingPhase 4
Tirzepatide for hot flashes in postmenopausal women with obesity
This study tests whether tirzepatide, a weekly injection, can reduce hot flashes and slow biological aging in postmenopausal women with obesity. It may help if you are experiencing bothersome hot flashes and are willing to follow a diet and exercise plan.
Jacksonville, FloridaAges 46–60 - NCT06975111RecruitingPhase 2/Phase 3
Improving health during menopause
This trial studies ways to help women during the late menopausal transition. It uses a smartphone app and telehealth visits to track your health and help you feel better.
Aurora, ColoradoAges 45–55 - NCT06743269Recruiting
Breathing Training for Stress and Sleep in Midlife Women
This study tests a simple breathing exercise (inspiratory muscle strength training) to see if it can help reduce stress and improve sleep for midlife women who have hot flashes. If you're between 45-60, have hot flashes, and don't smoke, you may be able to join.
Rochester, MinnesotaAges 45–60 - NCT06864520Recruiting
GABA supplement for menopause symptoms
This study tests whether a natural supplement containing GABA (a chemical that helps calm the brain) can reduce menopause symptoms like hot flashes, mood swings, and sleep problems. It may be a good option if you are looking for a non-hormonal way to manage your symptoms.
Genova, ItaliaAges Any age - NCT06716554Recruiting
Shatavari for menopausal symptoms in women
This study tests whether a natural herb called Shatavari can help with menopausal symptoms like hot flashes, sleep problems, and mood changes. It compares Shatavari to a placebo (a pill with no active ingredient) to see if it is safe and effective.
San Francisco, CaliforniaAges 45–55 - NCT07022925Recruiting
Wearable device for tracking hot flushes in perimenopause
This study will test if a wearable device can accurately track symptoms like hot flushes and night sweats in women going through perimenopause. If you are between 35 and 55 and experiencing these symptoms, your participation could help improve future symptom monitoring.
London, OntarioAges 35–55 - NCT06552091Recruiting
Digital self-hypnosis for hot flashes from hormone therapy
This trial tests a guided digital self-hypnosis program to help reduce hot flashes caused by hormone therapy for breast cancer. It aims to see if it can make hot flashes less frequent and bothersome.
Vandœuvre-lès-NancyAges 18 years+ - NCT06972875RecruitingPhase 2
Testing a hot flash pill for men on prostate cancer therapy
This trial tests a non-hormonal pill called fezolinetant to reduce hot flashes in men with prostate cancer who are on hormone therapy. If you have daily, bothersome hot flashes, this study may help you find relief.
Burlington, VermontAges 18 years+ - NCT07535541Recruiting
Smartwatch Study of Hot Flashes in Prostate Cancer Patients
This study tests whether a smartwatch can accurately measure hot flashes (sudden heat and sweating) that occur in men undergoing hormone therapy for prostate cancer. You'll wear the smartwatch for about 4 weeks while the research team tracks your symptoms.
Charlottesville, VirginiaAges 18 years+ - NCT07511660Enrolling by invitation
Ovarian cell injection for perimenopause symptom relief
This trial tests injecting special cells called Muse cells into the ovaries to help relieve perimenopause symptoms and possibly restore ovarian function. It may help women experiencing irregular periods, hot flashes, sleep problems, mood changes, or trouble thinking clearly.
Monterrey, Nuevo LeónAges 28–70 - NCT07422727Enrolling by invitation
Cooling Mat for Hot Flushes from Hormone Therapy
This trial tests whether a cooling mat can help reduce hot flushes and night sweats caused by hormone therapy for breast or prostate cancer. If you're bothered by these symptoms, you may be able to join.
Sligo, SligoAges 18 years+
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Hot Flashes trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for hot flashes?
- Yes. Clin2 currently lists 24 recruiting hot flashes studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hot flashes trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hot flashes trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.