Clinical trials
Human Papillomavirus clinical trials
Below are recruiting human papillomavirus clinical trials, each written for real people, not researchers. We’re tracking 66 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06686043RecruitingPhase 2
HPV vaccine, imiquimod, and metformin for advanced cervical or vulvar cancer
This trial tests a combination of an HPV vaccine, an immune cream (imiquimod), and a diabetes drug (metformin) together with standard chemoradiation. The goal is to see if this mix helps treat advanced cervical, vaginal, or vulvar cancers better than standard care alone.
Houston, TexasAges 18–64 - NCT07550010Recruiting
Digital Screening for Cervical Cancer in Cameroon
This study tests a new digital imaging method to help screen women for cervical cancer risk in Cameroon. It may help catch cervical problems earlier using easier-to-read pictures of the cervix.
YaoundéAges 25–50 - NCT06642324Recruiting
HPV and genetics in head and neck cancer study
This study looks at how HPV infection and genetic changes relate to head and neck squamous cell carcinoma. If you have this type of cancer, joining could help doctors learn more about the disease and improve future treatments.
Dhaka, Dhaka DivisionAges 18 years+ - NCT07461818Recruiting
Quick treatment for cervical pre-cancer
This trial tests a new way to quickly diagnose and treat cervical pre-cancer using a point-of-care device. It may help women who are HPV-positive avoid a separate treatment visit.
San Salvador, San Salvador DepartmentAges 30–49 - NCT06862102Recruiting
Multiple HPV Infections and Cervical Lesion Risk
This study looks at how having multiple types of HPV virus affects the development of abnormal cervical cells (called CIN). It may help doctors understand why some people are more at risk and could lead to better prevention.
Pavia, PaviaAges 18 years+ - NCT06650956Recruiting
HPV vaccine and health education for teens in Laos
This trial offers HPV vaccination and sexual health education to 10-13 year old students and out-of-school youth in Laos. It aims to improve health knowledge and vaccination rates.
Muang Sing, ProvinceAges 10–13 - NCT07301905Recruiting
HPV vaccine study for parents in Flint, MI
This study tests a culturally tailored health message to see if it helps parents feel more open to the HPV vaccine for their daughters. It focuses on families in Flint whose daughters have not yet received the vaccine.
Flint, MichiganAges 18 years+ - NCT07306260Recruiting
Photodynamic therapy for cervical pre-cancer
This study tests a light-based treatment called photodynamic therapy for cervical pre-cancer (CIN2). It may help remove abnormal cells while avoiding more invasive surgery, and aims to see if this treatment is safe and works well.
Hangzhou, ZhejiangAges 25–65 - NCT07290621RecruitingPhase 2
Toripalimab with standard treatment for HPV-positive throat cancer
This study tests adding a new immunotherapy drug (toripalimab) to standard chemo for HPV-positive throat cancer. It aims to see if this combination works better than chemo alone for patients whose cancer has spread to nodes but not to other parts of the body.
Chicago, IllinoisAges 18 years+ - NCT07281599Recruiting
Using a pad to screen for cervical precancer
This trial tests whether a special pad you wear during your period can detect signs of cervical precancer. If you are already scheduled for a colposcopy due to an abnormal Pap or HPV test, you might be able to participate.
New Haven, ConnecticutAges 25 years+ - NCT07209189RecruitingPhase 2
Chemo and immunotherapy before surgery for head and neck cancer
This trial tests a combination of chemotherapy and an immunotherapy drug called Toripalimab before surgery for certain head and neck cancers. The goal is to see if this approach can reduce the extent of treatment needed while still being effective.
Baltimore, MarylandAges 18 years+ - NCT07179315RecruitingPhase 2
Immunotherapy Study for HPV-Positive Head and Neck Cancer
This trial compares two different immunotherapy approaches for people with HPV-positive oropharyngeal cancer who have completed initial treatment like surgery, radiation, or chemotherapy. The goal is to see which option works better to keep the cancer from coming back, and eligibility is determined by a special blood test that detects HPV DNA.
Chicago, IllinoisAges 18 years+ - NCT05365048Recruiting
Promoting HPV vaccine visits in kids ages 9–12
This study looks at whether getting a provider recommendation helps more parents bring children ages 9–12 in for HPV vaccination. It may help increase vaccination uptake in pediatric clinics.
Pasadena, CaliforniaAges 21–70 - NCT06995157Recruiting
HPV infections and vaccine attitudes in Slovenian women
This observational study looks at HPV infections and women's views about the HPV vaccine in Slovenia. It aims to understand the characteristics of HPV infections and attitudes toward vaccination after the vaccine became available.
Ljubljana, Municipality of DomžaleAges Up to 35 years - NCT07033091Recruiting
HPV screening study for healthy adults 40 and older
This study checks healthy adults aged 40+ for HPV in the mouth using a simple gargle rinse. It aims to see if this can help find early signs of oropharyngeal cancer.
BrnoAges 40 years+ - NCT06942286Enrolling by invitation
HPV self-testing for cervical cancer screening in Indonesia
This study tests a home-based HPV self-collection kit for women who haven't been screened recently. The goal is to find cervical pre-cancer early, so treatment can prevent cancer.
Lebak, BantenAges 30–69 - NCT06219018RecruitingPhase 1/Phase 2
Testing honey for moderate cervical cell changes
This study tests whether honey applied directly to the cervix can help reverse moderate cervical cell changes (CIN II). It may offer a natural alternative to more invasive procedures.
Heerlen, LimburgAges 18–40 - NCT06815939Recruiting
A Simple, Lab-Free Test for Cervical Cancer
This trial is testing a new, low-cost, lab-free screening test for cervical cancer. The goal is to see if it can detect early signs of cancer without needing a doctor's visit or a lab — making it easier for women to get screened.
San SalvadorAges 30–59 - NCT06129253Recruiting
GLOBE-HPV: Study of HPV in communities
This study is trying to find out how many people in different communities have HPV (human papillomavirus). It involves collecting samples and answering questions to help estimate the global burden of HPV.
DhakaAges 9–50 - NCT06808776Recruiting
Stories to prevent HPV cancers
This trial tests if sharing stories can help parents decide to get their child the HPV vaccine. It is for parents of children ages 9 to 12 who have not yet started the HPV shot series.
Hershey, PennsylvaniaAges 18 years+ - NCT06797986RecruitingPhase 1/Phase 2
Vaccine for HPV-positive head and neck cancer
This trial tests an investigational vaccine called BVAC-E6E7 for head and neck cancer caused by HPV types 16 or 18 that has come back or spread. It is for people who have already tried standard treatments like platinum chemo or immunotherapy, or can't take them.
SeoulAges 19 years+ - NCT06574087Recruiting
Screening for anal cell changes in women with HPV related gynecological disease
This study looks at how often anal cell changes happen in women who have HPV-related gynecological problems. The goal is to find the best way to screen for these changes early.
Gdynia, Pomeranian VoivodeshipAges Any age - NCT06658405RecruitingPhase 2
HPV vaccine after cervical lesion treatment
This trial tests whether an HPV vaccine (Gardasil 9) can help women over 45 who still have HPV after treatment for a high-grade cervical lesion. It compares vaccinated and unvaccinated patients to see if vaccination lowers the risk of the lesion coming back.
LilleAges 45 years+ - NCT06598475Recruiting
Improving HPV vaccination in Latino teens at health centers
This trial tests a program to help community health centers recommend and boost HPV vaccination rates among Latino adolescents aged 11-12. It aims to support health care providers and staff with education and resources.
Houston, TexasAges 11–17
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Common questions
- Are there clinical trials for human papillomavirus?
- Yes. Clin2 currently lists 66 recruiting human papillomavirus studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a human papillomavirus trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a human papillomavirus trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.