Clinical trials · California
Long COVID clinical trials in California
We’re tracking 13 recruiting long covid studies with a site in California — including Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT06631287RecruitingPhase 3
Testing baricitinib for persistent long COVID symptoms
This trial tests whether the anti-inflammatory drug baricitinib can improve persistent long COVID symptoms like brain fog, fatigue, and shortness of breath. You may qualify if you had COVID-19 at least 6 months ago and still have bothersome symptoms that affect your daily life.
Los Angeles, CaliforniaAges 18 years+ - NCT06928272RecruitingPhase 3
Long COVID drug study for adults 18 to 65
This study tests whether a commonly used drug (repurposed) can help improve Long COVID symptoms like fatigue, breathing problems, or brain fog. It is for adults 18 to 65 who had COVID-19 in the past 4 years and still have symptoms after 3 months.
San Diego, CaliforniaAges 18–65 - NCT07123727RecruitingPhase 2
Testing Anktiva for long COVID symptoms
This study tests if the drug Anktiva can help people with long COVID. To join, you must have had at least one confirmed COVID-19 infection and now have lasting symptoms that started or got worse after that infection.
El Segundo, CaliforniaAges 18–70 - NCT07285707Recruiting
Acupuncture and herbs for long COVID
This small study tests whether acupuncture and Chinese herbal medicine can help relieve common long COVID symptoms like fatigue, cough, brain fog, and pain. It might be a good fit if you are struggling with ongoing symptoms after COVID and are looking for a treatment approach that isn't just more medication.
Whittier, CaliforniaAges 18 years+ - NCT06142253Recruiting
Water exercise for long COVID brain fog
This study tests whether water-based exercise (like swimming or water aerobics) helps veterans recover from long COVID, especially brain fog and memory problems. If you're a veteran with ongoing thinking issues after COVID-19, this may help you improve your symptoms over 8 months.
Palo Alto, CaliforniaAges 18–89 - NCT07108036RecruitingPhase 2
Testing Anktiva for Long COVID Symptoms
This trial tests a medicine called Anktiva to see if it can help people with Long COVID. It's for adults who had a confirmed COVID-19 infection and now have lasting symptoms like fatigue, brain fog, or trouble breathing.
San Francisco, CaliforniaAges 18–70 - NCT05741112Recruiting
Long COVID wearable study to track symptoms and help daily management
This study uses a wearable device to track symptoms and patterns in people with Long COVID, ME/CFS, and/or POTS. The goal is to see how wearable feedback and tracking tools may help you manage your symptoms.
La Jolla, CaliforniaAges 18 years+ - NCT06257420Enrolling by invitation
Low-dose rapamycin for ME/CFS and Long-COVID
This trial tests whether a low dose of rapamycin, a drug that may help regulate the immune system, can improve symptoms in people with ME/CFS or Long-COVID.
Palo Alto, CaliforniaAges 18–65 - NCT04978571Recruiting
Electrical nerve stimulation for long-lasting concussion symptoms
This study tests whether a device that delivers gentle electrical signals to nerves through the skin can help children and teens with concussion symptoms that have lasted at least 3 months. You may be asked to attend clinic visits for the nerve stimulation setup if you meet the safety and scheduling requirements.
Orange, CaliforniaAges 11–18 - NCT07074158Enrolling by invitation
Looking for long COVID clues in blood
This study compares the blood of people with ongoing long COVID symptoms to healthy people, to look for differences in immune signals and gut bacteria. It could help find better ways to diagnose or treat long COVID.
Palo Alto, CaliforniaAges 18 years+ - NCT05131594Enrolling by invitation
Study immune response in Long COVID patients
This trial studies how your immune system responds in people with Long COVID after a past COVID-19 infection. It may help researchers understand why symptoms linger and how the body’s response could be targeted.
Pasadena, CaliforniaAges 18 years+ - NCT05833217Recruiting
Study for persistent COVID symptoms with insulin resistance
This trial studies people who have ongoing effects after COVID (often called PASC) and may be related to weight and insulin resistance. It may help researchers find better ways to understand the condition and improve treatment.
Palo Alto, CaliforniaAges 18–80 - NCT04362150Recruiting
Study of long-term effects after COVID-19 infection
This study follows adults who had COVID-19 to learn how the illness can affect health over the long term. It may help researchers understand lasting symptoms and who is at higher risk, which could improve future care.
San Francisco, CaliforniaAges 18–100
Long COVID trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting long covid studies listed above.
- University of California, San Francisco · 2 studies
- Center For Complex Diseases
- Chan Soon-Shiong Institute for Medicine
- CHOC Children's Hospital
- Clinical and Translational Research Unit
- Huntington Memorial Hospital
- Laura Rodriguez Research Institute
- Scripps Research
What taking part in a long covid study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Long COVID trials in other states
Common questions
- Are there long covid clinical trials in California?
- Yes. We're currently tracking 13 recruiting long covid studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a long covid study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a long covid trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New long covid studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.