Clinical trials
Lymphedema clinical trials
Below are recruiting lymphedema clinical trials, each written for real people, not researchers. We’re tracking 99 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04606030Recruiting
Tested lymph surgery for breast-cancer–related arm swelling
This trial studies a specialized lymph surgery (called VLNT, moving lymph tissue) to treat swelling in an arm caused by breast cancer treatment. It may help reduce lymphedema that doesn’t fully improve with compression and elevation.
Chicago, IllinoisAges 18–75 - NCT04687956Recruiting
Preventing arm swelling after breast cancer lymph node surgery
This study looks at ways to prevent arm swelling (lymphedema) related to breast cancer after surgery to remove lymph nodes. It may help people who are getting axillary lymph node dissection lower the chance of long-term swelling.
SeoulAges 19 years+ - NCT05064176Recruiting
Reconstructive lymph surgery plus usual care for lymphoedema
This study tests whether adding a reconstructive lymph surgery to standard lymphoedema care improves symptoms and function. It may help people with moderate lymphoedema who have already tried therapy for several months.
GhentAges 18 years+ - NCT05264337Recruiting
Study for swelling after prostate or other urinary surgery
This study looks at swelling caused by lymph fluid buildup after urinary (urologic) surgery that removes lymph nodes. If you’re scheduled for or recently had this type of surgery, this trial may help researchers understand how to prevent or treat this swelling.
GothenburgAges 18 years+ - NCT05269264Recruiting
Screening and diagnostic test for leg swelling from lymphedema
This trial is developing a tool to screen for, diagnose, and evaluate lower-limb lymphedema (leg swelling caused by lymph fluid). It may help patients get a more accurate diagnosis and better monitoring of their condition.
LeuvenAges 18 years+ - NCT05469945Recruiting
Prevention study for leg swelling after gynecologic cancer treatment
This study looks at what to do to help prevent or better manage leg swelling (lymphedema) after treatment for certain gynecologic cancers. You may be asked to use a diary or app and complete questionnaires so the team can track symptoms over time.
GhentAges 18–99 - NCT05601037Recruiting
Surgery to reduce lymphedema risk after breast lymph node removal
This trial looks at a preventive surgical technique done during breast lymph node removal to lower the chance of developing lymphedema (swelling from blocked fluid) after treatment. If you are at risk, it may help reduce long-term swelling and discomfort.
Ghent, Oost-VlaanderenAges 18–99 - NCT05629026Recruiting
Study of lymph blockage in lymphedema after breast cancer
This study looks at lymphatic “drainage” problems (lymphedema) and how they develop after breast cancer treatment. It may help doctors better understand lymphedema and improve care for people who meet the study safety requirements.
ToulouseAges 18–75 - NCT05695924Recruiting
Surgery to reduce arm swelling after breast cancer
This trial studies whether a specific surgery (a lymph vessel transplant) can reduce upper-arm lymphedema in people who developed swelling after breast cancer treatment. You must already have tried standard therapy and still have persistent, mild-to-moderate swelling.
Stanford, CaliforniaAges 18–75 - NCT05804643Recruiting
MRI scans to study swelling from breast cancer
This study uses special MRI (a detailed body scan) to better evaluate arm or hand swelling caused by breast-cancer–related lymphedema. It may help doctors understand how to measure lymphedema more accurately.
TaipeiAges 20 years+ - NCT05890677Recruiting
Surgery versus conservative care for chronic breast-related arm swelling
This trial compares microsurgery to standard conservative therapy for long-lasting arm swelling caused by prior breast cancer. It may help people who still have swelling despite months of decongestive treatment by improving quality of life.
New Haven, ConnecticutAges 18 years+ - NCT05962827Recruiting
Testing Lp(a) lipoprotein in people with lymphedema
This study looks at a blood marker called Lp(a) in adults who have lymphedema. The goal is to understand whether checking Lp(a) is important for people with this condition.
Nice, FranceAges 18–99 - NCT06038864Recruiting
New screening tool for leg lymphedema
This study is testing a new tool to help doctors screen, diagnose, and track leg swelling (lymphedema). It involves two groups: people starting intensive treatment and people who are already on maintenance therapy.
LeuvenAges 18 years+ - NCT06046365Recruiting
Early detection of arm swelling after breast cancer surgery
This trial tests a new way to measure arm swelling (lymphedema) early in women who have had or will have breast cancer surgery. It aims to catch swelling sooner so treatment can start faster.
Kaohsiung CityAges 20–80 - NCT06125743Recruiting
Self-management program for head and neck swelling
This study tests a self-management program to help people with head and neck cancer manage swelling (lymphedema) and tightness (fibrosis) after treatment. It may be a good fit if you have finished cancer therapy, are cancer-free, and have access to internet at home.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06228937Recruiting
Gut bacteria and lymphedema with repeated infections
This study looks at the bacteria in your gut and how they relate to lymphedema (swelling) and repeated skin infections in the affected limb. It compares people who have many infections with those who have none, to better understand why some get infections and others don't.
RomeAges 18–85 - NCT06235463Recruiting
Pedal pump for leg lymphedema
This trial tests whether a foot pump can help reduce leg swelling in older adults with lymphedema. It is a low-risk, non-drug approach that you can do at home.
Stratford, New JerseyAges 55–100 - NCT06321653Recruiting
Lymphedema after radiation for early breast cancer with 1-2 positive nodes
This trial aims to see if a shorter course of radiation after breast-conserving surgery affects arm swelling (lymphedema) in people with early breast cancer that has spread to 1 or 2 nearby lymph nodes. The goal is to learn if this approach is safe and effective.
MilanAges 18 years+ - NCT06325618Recruiting
Studying lymphedema and blood vessels in Turner syndrome
This study looks at swelling (lymphedema), inflammation, and blood vessels in women with Turner syndrome. It uses MRI scans to understand these issues better.
Aarhus NAges 18–100 - NCT04258319Enrolling by invitation
Limb fluid swelling study using arm and leg motion tests
This study looks at how swollen fluid (lymphedema) behaves in the arms and legs using measurements taken from your movement. It aims to better understand the changes in limb tissue, which could help guide future care.
Jacksonville, FloridaAges 18 years+ - NCT06454734Recruiting
Shock wave therapy for leg lymphedema
This trial tests if shock wave therapy can help reduce leg swelling caused by lymphedema. It is for people with moderate to severe swelling that has affected at least the knee to foot area for 6 months or longer.
BarcelonaAges 18 years+ - NCT06494111RecruitingPhase 2
Preventing neck swelling after radiation for throat cancer
This study tests two medicines—pravastatin (a statin) and a combination of pentoxifylline and Vitamin E—to see if they can prevent long-term swelling (lymphedema) and scarring in the neck after radiation therapy for throat cancer. Participants receive one of the medicines daily for 2 years, and regular scans help monitor any changes.
Houston, TexasAges 18 years+ - NCT06697158Recruiting
Lymphedema therapy and its effect on sleep and quality of life
This study tests a treatment called complex decongestive physiotherapy for women who have swelling in one arm after breast cancer surgery. It looks at whether this therapy can improve their sleep and overall quality of life.
BoluAges 18–85 - NCT06708754Recruiting
Light therapy for radiation side effects in head and neck cancer
This study tests if a special light therapy (photobiomodulation) can help reduce tissue stiffness and swelling caused by radiation for head and neck cancer. It may be an option if you finished radiation in the last 3 years and have moderate to severe scarring or swelling.
New York, New YorkAges 18 years+
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Common questions
- Are there clinical trials for lymphedema?
- Yes. Clin2 currently lists 99 recruiting lymphedema studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lymphedema trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lymphedema trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.