Clinical trials
Lymphedema clinical trials
Below are recruiting lymphedema clinical trials, each written for real people, not researchers. We’re tracking 96 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06494111RecruitingPhase 2
Preventing neck swelling after radiation for throat cancer
This study tests two medicines—pravastatin (a statin) and a combination of pentoxifylline and Vitamin E—to see if they can prevent long-term swelling (lymphedema) and scarring in the neck after radiation therapy for throat cancer. Participants receive one of the medicines daily for 2 years, and regular scans help monitor any changes.
Houston, TexasAges 18 years+ - NCT06399367Enrolling by invitation
New imaging for leg swelling conditions
This study uses a special imaging machine (MSOT) to look at different types of swelling in the legs, such as lipedema and lymphedema. It aims to help doctors better understand and tell these conditions apart.
Göttingen, Lower SaxonyAges 18–80 - NCT06306274Enrolling by invitationPhase 2/Phase 3
Tacrolimus cream for breast cancer-related lymphedema
This study tests if a cream called tacrolimus can help reduce swelling in the arm caused by breast cancer treatment (lymphedema). It is looking for women with mild to moderate swelling that has not yet caused severe skin changes.
OdenseAges 18 years+ - NCT06228937Recruiting
Gut bacteria and lymphedema with repeated infections
This study looks at the bacteria in your gut and how they relate to lymphedema (swelling) and repeated skin infections in the affected limb. It compares people who have many infections with those who have none, to better understand why some get infections and others don't.
RomeAges 18–85 - NCT06125743Recruiting
Self-management program for head and neck swelling
This study tests a self-management program to help people with head and neck cancer manage swelling (lymphedema) and tightness (fibrosis) after treatment. It may be a good fit if you have finished cancer therapy, are cancer-free, and have access to internet at home.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05962827Recruiting
Testing Lp(a) lipoprotein in people with lymphedema
This study looks at a blood marker called Lp(a) in adults who have lymphedema. The goal is to understand whether checking Lp(a) is important for people with this condition.
Nice, FranceAges 18–99 - NCT05890677Recruiting
Surgery versus conservative care for chronic breast-related arm swelling
This trial compares microsurgery to standard conservative therapy for long-lasting arm swelling caused by prior breast cancer. It may help people who still have swelling despite months of decongestive treatment by improving quality of life.
New Haven, ConnecticutAges 18 years+ - NCT05825157Recruiting
Tested combined treatment for arm swelling after cancer
This study looks at a combination treatment to improve swelling in one arm caused by lymphedema. You may be a good candidate if your arm swelling has not fully improved with standard compression therapy and you are able to have surgery.
Palo Alto, CaliforniaAges 18–75 - NCT03991897Recruiting
Keto diet to treat early arm swelling after lymph node removal
This study tests whether a ketogenic (keto) diet can reduce arm lymphedema (swelling) that started within the last year after lymph node removal. It aims to improve swelling by changing the body’s metabolism.
LeuvenAges 18 years+ - NCT05629026Recruiting
Study of lymph blockage in lymphedema after breast cancer
This study looks at lymphatic “drainage” problems (lymphedema) and how they develop after breast cancer treatment. It may help doctors better understand lymphedema and improve care for people who meet the study safety requirements.
ToulouseAges 18–75 - NCT05264337Recruiting
Study for swelling after prostate or other urinary surgery
This study looks at swelling caused by lymph fluid buildup after urinary (urologic) surgery that removes lymph nodes. If you’re scheduled for or recently had this type of surgery, this trial may help researchers understand how to prevent or treat this swelling.
GothenburgAges 18 years+ - NCT04258319Enrolling by invitation
Limb fluid swelling study using arm and leg motion tests
This study looks at how swollen fluid (lymphedema) behaves in the arms and legs using measurements taken from your movement. It aims to better understand the changes in limb tissue, which could help guide future care.
Jacksonville, FloridaAges 18 years+ - NCT04123457Enrolling by invitation
Study blood and skin samples to improve lymphedema care
This study collects samples (like blood and possibly lymph fluid-related tests) to help doctors better tailor treatment for lymphedema. It may help researchers find ways to improve outcomes for people treated for swollen, fluid-rich tissue.
Jacksonville, FloridaAges 18 years+ - NCT03248310Recruiting
Surgery vs non-surgical care for lymphedema quality of life
This study compares how people feel day to day (quality of life) after either surgery or non-surgical care for lymphedema. It may help doctors understand which approach improves comfort, function, and overall well-being.
Harrison, New YorkAges 18–80 - NCT02743858Recruiting
Watch swelling study after breast lymph node surgery
This study looks at how and when swelling (lymphedema) happens after breast cancer surgery on the armpit lymph nodes. You may be followed closely after your planned one-sided procedure to better understand who gets swelling and how it changes over time.
Basking Ridge, New JerseyAges 18 years+ - NCT04356235Recruiting
Comparing immediate vs delayed breast implant reconstruction results
This study compares two timing options for rebuilding the breast with implants, looking at cosmetic results, quality of life, and patient satisfaction. It may help you understand which approach could fit you better and what to expect over follow-up time.
BudapestAges 18–65 - NCT04345081Recruiting
Compare two breast surgery skin-sparing methods and recovery
This trial compares two types of mastectomy (with skin and nipple options) and implant reconstruction to see which gives better cosmetic results, comfort, and satisfaction. You may help doctors learn which approach leads to a better quality of life after surgery.
BudapestAges 18–65 - NCT07780240Recruiting
Understanding arm band pain after breast cancer surgery
This study looks at how common axillary web syndrome (a rope-like band in the armpit after breast cancer surgery) is, who gets it, and how it affects arm function. It aims to help doctors better predict and manage this condition.
Istanbul, BAGCILARAges 18–80 - NCT07743294Recruiting
Exercise before breast cancer surgery to reduce arm swelling
This trial tests whether doing specific exercises before breast cancer surgery helps reduce arm swelling (lymphedema) after surgery, and improves quality of life and care needs. You would participate in a supervised exercise program before your surgery and then follow up after.
TaipeiAges 20 years+ - NCT07708662Recruiting
Boosted compression for long-term leg swelling
This trial tests a stronger compression method for people with long-lasting leg swelling (edema) that is not caused by another medical condition. The goal is to see if it works better than standard care.
Edegem, AntwerpAges 18 years+ - NCT05725265Recruiting
Low-level laser treatment for arm swelling after breast cancer
This study tests whether low-level laser therapy can safely reduce swelling in one arm caused by breast-cancer treatment. It compares the laser to a look-alike inactive (placebo) treatment and checks changes over time.
TaipeiAges 20 years+ - NCT07694726Recruiting
Vein repair during neck surgery to prevent lymphedema
This study tests whether repairing veins during head and neck cancer surgery helps prevent lymphedema (painful swelling) after treatment. It may help patients who are having lymph node removal and will receive radiation afterward.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07576270Recruiting
Breathing exercises and massage after breast cancer surgery
This study tests whether special breathing exercises and massage techniques can help reduce pain, stiffness, and limited arm movement in people who've had breast cancer surgery. It may help improve shoulder function and quality of life after treatment.
Lahore, Punjab ProvinceAges 45–64 - NCT07561411Recruiting
Nerve blocks to reduce pain after breast removal surgery
This trial tests two types of nerve-blocking injections given during breast removal surgery to see which one better prevents long-term pain afterward. Both are given alongside general anesthesia and may help you recover with less chronic pain.
BeirutAges 18–80
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Common questions
- Are there clinical trials for lymphedema?
- Yes. Clin2 currently lists 96 recruiting lymphedema studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lymphedema trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lymphedema trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.