Clinical trials
Lymphedema clinical trials
Below are recruiting lymphedema clinical trials, each written for real people, not researchers. We’re tracking 99 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06837480Recruiting
Light therapy for long-term swelling after head and neck cancer
This study tests a light-based treatment called photobiomodulation (PBMT) to help reduce chronic swelling after head and neck cancer therapy. It is for people whose swelling hasn’t improved with standard treatment.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06839885Recruiting
Water Therapy for Swelling in One Leg
This trial tests whether water-based therapy (hydrotherapy) can help reduce swelling in one leg caused by lymphedema. It's for people who have already tried standard lymphedema treatment.
IstanbulAges 18–75 - NCT06989099RecruitingPhase 2
Preventing lymphedema with immediate lymphatic reconstruction
This study tests if performing immediate lymphatic reconstruction during lymph node removal can prevent lymphedema (arm swelling) in women with inflammatory breast cancer. If you qualify, the procedure may help lower your risk of long-term swelling.
Houston, TexasAges 18 years+ - NCT07012642RecruitingEarly Phase 1
GLP-1 drugs for arm or leg swelling (lymphedema)
This trial tests if a class of diabetes drugs (GLP-1 receptor agonists) can reduce swelling in one arm or leg caused by lymphedema. It may help people who have not found relief from other treatments.
Red Bank, New JerseyAges 18 years+ - NCT07080476Recruiting
Kinesio taping for chronic swelling after breast cancer
This trial tests whether Kinesio taping, a special type of elastic tape, can reduce long-term swelling in the breast or upper body (trunk) after breast cancer treatment. If you have had breast cancer and still have swelling lasting more than six months, this study may help find a new way to manage that swelling.
AntwerpAges 18 years+ - NCT07233863Recruiting
Lymphovenous bypass for preventing lymphedema in breast cancer
This trial tests a surgery (lymphovenous bypass) to prevent or slow down lymphedema (arm swelling) in breast cancer patients who have already had lymph nodes removed. It may help those with early-stage lymphedema who haven't tried physical therapy yet.
Jakarta, Jakarta Special Capital RegionAges 18 years+ - NCT07257679RecruitingPhase 4
Gentle touch for arm swelling after breast cancer surgery
This study tests a gentle hand-on technique (called Gentle Touch) to see if it helps reduce arm swelling in women who developed lymphedema after breast cancer surgery. It may offer a new way to manage this side effect.
Roma, RMAges 30–75 - NCT02743858Recruiting
Watch swelling study after breast lymph node surgery
This study looks at how and when swelling (lymphedema) happens after breast cancer surgery on the armpit lymph nodes. You may be followed closely after your planned one-sided procedure to better understand who gets swelling and how it changes over time.
Basking Ridge, New JerseyAges 18 years+ - NCT07472543Recruiting
Virtual reality exercises for leg lymphedema after cancer surgery
This trial tests whether virtual reality-based exercises can help reduce leg swelling caused by lymphedema after gynecological or other cancer surgery. It may be a good option if you have lymphedema in one leg and can commit to daily sessions for a month.
AnkaraAges 18–65 - NCT07489248Recruiting
Ultrasound study for lymphedema vs. lipedema
This study uses special ultrasound techniques to help doctors tell the difference between lymphedema (fluid swelling) and lipedema (fat swelling) in the legs. If you have one of these conditions or have healthy legs, you may be able to join.
Kayseri, KocasinanAges 18–75 - NCT07558317Recruiting
Resistance Exercise for Lower Leg Swelling
This study tests whether strength-training exercises can help reduce swelling in the lower leg caused by lymphedema. You'll wear compression garments as usual and add supervised resistance exercises to see if they improve your symptoms and quality of life.
HerlevAges 18 years+ - NCT07198698Enrolling by invitation
Sahid method for leg swelling after surgery, infection, or treatment
This study tests a technique called the Sahid method to reduce leg swelling (lymphedema) in women. It might help if you have had swelling in one leg for two years or less due to surgery, infection, cancer, or an injury.
SantiagoAges 30–65 - NCT06652295Enrolling by invitation
Self-physiotherapy for lymphedema
This trial tests whether a self-guided physiotherapy program can help manage lymphedema (arm swelling) after breast cancer treatment. If you have had breast cancer-related lymphedema for a while and haven't had recent treatment for it, this study may offer a way to take control of your symptoms.
IzmirAges 18–65 - NCT06399367Enrolling by invitation
New imaging for leg swelling conditions
This study uses a special imaging machine (MSOT) to look at different types of swelling in the legs, such as lipedema and lymphedema. It aims to help doctors better understand and tell these conditions apart.
Göttingen, Lower SaxonyAges 18–80 - NCT06306274Enrolling by invitationPhase 2/Phase 3
Tacrolimus cream for breast cancer-related lymphedema
This study tests if a cream called tacrolimus can help reduce swelling in the arm caused by breast cancer treatment (lymphedema). It is looking for women with mild to moderate swelling that has not yet caused severe skin changes.
OdenseAges 18 years+ - NCT04123457Enrolling by invitation
Study blood and skin samples to improve lymphedema care
This study collects samples (like blood and possibly lymph fluid-related tests) to help doctors better tailor treatment for lymphedema. It may help researchers find ways to improve outcomes for people treated for swollen, fluid-rich tissue.
Jacksonville, FloridaAges 18 years+ - NCT07743294Recruiting
Exercise before breast cancer surgery to reduce arm swelling
This trial tests whether doing specific exercises before breast cancer surgery helps reduce arm swelling (lymphedema) after surgery, and improves quality of life and care needs. You would participate in a supervised exercise program before your surgery and then follow up after.
TaipeiAges 20 years+ - NCT06912763RecruitingPhase 2
Reversing radiation side effects in head and neck cancer
This trial tests a combined treatment (a statin and a drug that helps blood flow) to reverse long-term swelling and tissue hardening caused by head and neck radiation. It may help people who have had these side effects for more than 6 months.
Houston, TexasAges Any age - NCT07708662Recruiting
Boosted compression for long-term leg swelling
This trial tests a stronger compression method for people with long-lasting leg swelling (edema) that is not caused by another medical condition. The goal is to see if it works better than standard care.
Edegem, AntwerpAges 18 years+ - NCT03941756Recruiting
Lymph bypass before underarm node surgery to prevent swelling
This study looks at whether adding a lymph “bypass” procedure before underarm lymph node surgery can lower the chance of arm or chest swelling (lymphedema) after cancer treatment. It compares people having lymph node surgery for breast cancer with plans for radiation, and a melanoma comparison group.
Houston, TexasAges 18 years+ - NCT04194619Recruiting
Study of pregnancy safety in women with rare blood-vessel diseases
This study looks at pregnancy and the early period after birth in women with rare diseases that affect blood vessels. It may help doctors understand risks and improve care for future pregnancies.
AngersAges 18–45 - NCT04345081Recruiting
Compare two breast surgery skin-sparing methods and recovery
This trial compares two types of mastectomy (with skin and nipple options) and implant reconstruction to see which gives better cosmetic results, comfort, and satisfaction. You may help doctors learn which approach leads to a better quality of life after surgery.
BudapestAges 18–65 - NCT04356235Recruiting
Comparing immediate vs delayed breast implant reconstruction results
This study compares two timing options for rebuilding the breast with implants, looking at cosmetic results, quality of life, and patient satisfaction. It may help you understand which approach could fit you better and what to expect over follow-up time.
BudapestAges 18–65 - NCT06725030Recruiting
Robotic surgery for lymphedema (Symani System)
This trial uses a robotic arm called Symani to help surgeons perform more precise microsurgery (working on tiny blood vessels and lymph channels). It is for adults with moderate lymphedema in one arm or leg who have already tried standard lymphedema therapy and still have swelling.
Beverly Hills, CaliforniaAges 22 years+
Hear when a new Lymphedema trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for lymphedema?
- Yes. Clin2 currently lists 99 recruiting lymphedema studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lymphedema trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lymphedema trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.