Clinical trials
Lymphedema clinical trials
Below are recruiting lymphedema clinical trials, each written for real people, not researchers. We’re tracking 99 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05300308Recruiting
Studying leg swelling and nighttime urination after pelvic node surgery
This trial looks at why some people develop leg swelling (lymphedema) and frequent nighttime urination (nocturia) after pelvic lymph node surgery for prostate or bladder cancer. It may help doctors better predict and manage these side effects after the operation.
Leuven, FlandersAges 18 years+ - NCT05628948Recruiting
Donate blood for a heart and metabolism research biobank
This study builds a “biobank,” which is a collection of blood and related samples, to support future research on heart and metabolic (sugar/body-fat) conditions. It may help researchers better understand these diseases and improve future prevention and treatments.
Cleveland, OhioAges 18 years+ - NCT05725265Recruiting
Low-level laser treatment for arm swelling after breast cancer
This study tests whether low-level laser therapy can safely reduce swelling in one arm caused by breast-cancer treatment. It compares the laser to a look-alike inactive (placebo) treatment and checks changes over time.
TaipeiAges 20 years+ - NCT05910411Recruiting
Compression treatment for leg swelling after blood-flow surgery
This trial studies whether a specific type of compression helps reduce swelling in the leg after a bypass surgery to improve blood flow. It may help people manage “edema” (fluid-related swelling) while healing after revascularization.
Nice, FranceAges 18–99 - NCT06041958Recruiting
Shock Wave and Pulsed Field Therapy for Lymphedema
This trial tests two non-invasive therapies—shock wave therapy and pulsed electromagnetic field therapy—to see if they can reduce arm or leg swelling (lymphedema) caused by cancer treatment. It's for people who are at least 20 and have had breast or gynecologic cancer.
Kaohsiung CityAges 20–80 - NCT06092892RecruitingPhase 2
Upfront targeted lymph node removal for early breast cancer
This trial is for women age 45 and older with early ER-positive breast cancer that has spread to the lymph nodes under the arm. It tests a surgery approach where the main tumor and only a few key lymph nodes (rather than many) are removed.
Los Angeles, CaliforniaAges 45 years+ - NCT06297265Recruiting
Gentle breast massage after lumpectomy for breast cancer
This trial studies whether a special gentle massage technique (manual lymphatic drainage) can help women who have had breast-conserving surgery and will receive whole breast radiation. The goal is to see if it reduces side effects and improves recovery.
Los Angeles, CaliforniaAges 18 years+ - NCT06418282Recruiting
Portable compression device for leg swelling
This study tests a new portable device that wraps around your leg to gently squeeze and reduce swelling from lymphedema or vein problems. It aims to see if at-home use can improve symptoms and lower healthcare costs compared to standard care.
New York, New YorkAges 18–100 - NCT06421285Recruiting
Exercise before breast cancer surgery to prevent lymphedema
This trial tests whether doing exercise before surgery can help prevent arm swelling (lymphedema) in women being treated for breast cancer. If you are newly diagnosed, facing chemotherapy first, and can exercise safely, this study might be a good fit.
Seoul, Seoul Special CityAges 20–80 - NCT06495034Recruiting
Airwave compression to prevent arm swelling after breast cancer surgery
This trial tests whether wearing a special airwave compression sleeve after breast cancer surgery can prevent arm swelling (lymphedema). It is for women who are about to have lymph node surgery under their arm.
Shantou, GuangdongAges 18–70 - NCT06574022RecruitingPhase 4
Comparing two pain blocks for mastectomy recovery
This trial compares two types of pain blocks (PECS-II and pectoral blocks) to see which works better after mastectomy. The goal is to improve pain control and recovery for patients with breast cancer or high risk.
Cincinnati, OhioAges 18 years+ - NCT06082206Recruiting
Nerve blocks to prevent long-term pain after breast cancer surgery
This study compares two types of nerve blocks (pectoral nerve block vs. paravertebral block) to see which one better prevents long-term pain after breast cancer surgery.
AsyutAges 20–65 - NCT06866197Recruiting
Robotic system for microsurgery in lymphedema and free flap
This study tests a robotic system (Symani) to help surgeons perform very precise microsurgery, either to reconnect tiny blood vessels during a free flap procedure or to treat lymphedema (chronic swelling). It may help people with lymphedema who have not gotten full relief from compression therapy.
Melbourne, VictoriaAges 18–100 - NCT07127003Recruiting
Surgical bypass to prevent arm swelling after lymph node removal
This study tests a surgical bypass (called ILR) to prevent arm swelling (lymphedema) after removing lymph nodes from under the arm during breast cancer surgery. The goal is to see if this extra step helps keep your arm healthy.
Tampa, FloridaAges 18–75 - NCT07154043Recruiting
Comparing compression pump vs. massage for arm swelling
This study compares two therapies for breast cancer-related arm swelling (lymphedema): one uses a machine that pumps air around your arm (intermittent pneumatic compression, or IPC), and the other is a special type of massage (manual lymph drainage, or MLD). The goal is to see if the machine works as well as or better than massage for reducing swelling.
DenizliAges 18–65 - NCT07236658Recruiting
Using AI to detect arm problems after breast cancer surgery
This trial uses artificial intelligence (a computer program) to help predict arm and shoulder problems that can happen after breast cancer surgery. It aims to find these issues early so they can be treated better.
AnkaraAges 18 years+ - NCT07297927Recruiting
ICG Imaging of Arm Lymphatics Before and After Breast Radiation
This study looks at whether radiation therapy changes the flow of lymph fluid in the arm on the side where you had breast cancer. It uses a special dye (ICG) to take pictures of your lymph vessels before and after radiation, to help find ways to prevent arm swelling (lymphedema).
Hwaseong-si, GyeonggidoAges 18 years+ - NCT02280733Recruiting
Chronic wound registry for real-world care documentation
This study is a real-world registry that collects information about chronic wounds and ulcers as they’re treated in everyday settings. It may help improve how care is tracked and supported, even if you don’t get a new medicine from the study.
The Woodlands, TexasAges Any age - NCT00833599Enrolling by invitation
Scan lymph drainage and collect samples for related conditions
This study uses a special light scan after a dye is given to look at how your lymph system drains. It may also include genetic testing for people with a family history of lymph-related disorders to better understand causes.
Houston, TexasAges 3 months+ - NCT07472803Recruiting
Body composition study in early breast cancer patients
This study looks at how body composition (muscle and fat) changes over time in people with early-stage breast cancer. It aims to better understand the effects of cancer treatment on the body.
New Taipei City, Xindian DistAges 18 years+ - NCT07561411Recruiting
Nerve blocks to reduce pain after breast removal surgery
This trial tests two types of nerve-blocking injections given during breast removal surgery to see which one better prevents long-term pain afterward. Both are given alongside general anesthesia and may help you recover with less chronic pain.
BeirutAges 18–80 - NCT07576270Recruiting
Breathing exercises and massage after breast cancer surgery
This study tests whether special breathing exercises and massage techniques can help reduce pain, stiffness, and limited arm movement in people who've had breast cancer surgery. It may help improve shoulder function and quality of life after treatment.
Lahore, Punjab ProvinceAges 45–64 - NCT06786091Enrolling by invitation
Managing late side effects after cervical cancer treatment
This study looks at ways to prevent and treat late side effects that can happen after cervical cancer treatment. It may help if you were treated with surgery, radiation, or chemotherapy in the last five years.
Trondheim, TrøndelagAges 18–80 - NCT06572098Enrolling by invitation
Lymphedema therapy and its effect on stress and antioxidants
This trial tests if a special therapy for arm swelling (lymphedema) after breast cancer treatment can reduce oxidative stress (a sign of cell damage) and boost antioxidants. It may help you if you have stage 2 or 3 lymphedema.
Adana, çukurovaAges 25 years+
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Common questions
- Are there clinical trials for lymphedema?
- Yes. Clin2 currently lists 99 recruiting lymphedema studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lymphedema trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lymphedema trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.