Clinical trials
Macular Edema clinical trials
Below are recruiting macular edema clinical trials, each written for real people, not researchers. We’re tracking 53 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06962839RecruitingPhase 2
Study of BI 1815368 for diabetic macular edema
This trial tests an experimental medication (BI 1815368) given as an eye injection for people with diabetic macular edema, a condition where fluid builds up in the center of the retina and blurs vision. The study aims to see if this new treatment can reduce swelling and improve vision.
Phoenix, ArizonaAges 18 years+ - NCT06845163RecruitingPhase 2
Testing dapagliflozin for diabetic macular edema
This study tests whether a medication called dapagliflozin, which is usually used for diabetes and heart failure, can help reduce swelling in the retina (diabetic macular edema) and improve vision. It is for people with type 2 diabetes who are already taking insulin and metformin.
Alexandria, Alexandria GovernorateAges 18–85 - NCT05802329RecruitingPhase 1
Testing eye injections for diabetic macular swelling
This Phase 1 study tests the safety and early effectiveness of OCU200 eye injections in people with diabetic macular edema (DME) that affects the center of vision. It may help by reducing the eye swelling that blurs vision from diabetes.
Deerfield Beach, FloridaAges 18 years+ - NCT04187443RecruitingPhase 1
Drug MS-553 for diabetic eye swelling with reduced vision
This Phase 1 trial tests MS-553 to see how it works and how safely it can be given to people with diabetic retinopathy causing central macular swelling (macular edema). You may be considered if your vision and eye scan results match, and if you can follow frequent study visits.
Changsha, HunanAges 18 years+ - NCT06305416RecruitingPhase 3
Ranibizumab for diabetic macular edema
This trial tests an injection called Ranibizumab (10 mg/ml) to treat diabetic macular edema, a condition where fluid builds up in the center of the retina and causes blurry vision. The goal is to see if the drug is safe and effective at improving vision.
DhakaAges 18 years+ - NCT06595355RecruitingPhase 2/Phase 3
Study of eye injections with or without curcumin for diabetic eye swelling
This trial tests whether adding oral curcumin (a natural supplement) to standard eye injections (bevacizumab) improves treatment for diabetic macular edema, a swelling in the back of the eye that can affect vision.
Isfahan, Isfahan University of Medical SciencesAges 40 years+ - NCT06825702RecruitingPhase 2
Testing KIO-104 eye injection for macular edema
This trial tests an eye injection called KIO-104 to treat macular edema (swelling in the center of the retina) caused by conditions like uveitis, diabetes, or vein blockage. The goal is to see if it is safe and improves vision.
Sydney, New South WalesAges 18–85 - NCT06511700Enrolling by invitation
Nurse-led eye injections: a new care approach
This trial tests whether specially trained nurses can safely give eye injections instead of doctors. It may make treatment quicker and easier for people who need regular injections for eye conditions.
Sabadell, BarcelonaAges 18 years+ - NCT05916391RecruitingPhase 1
Gene therapy for diabetic macular swelling affecting vision
This early-stage (Phase 1) study tests a new gene therapy to improve vision for adults with diabetic macular edema. It mainly looks at whether the treatment can be safely given and may help your vision over time.
Tianjin, Tianjin,ChinaAges 18 years+ - NCT05728476Recruiting
Compare eye surgery plus peeling versus anti-VEGF injections
This trial compares a minimally invasive eye procedure (vitrectomy with peeling) versus anti-VEGF injections to treat new diabetic macular edema in people who have not had treatment yet. It looks at which option improves vision and eye swelling for people with diabetes.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT07515079RecruitingPhase 3
Testing BAT5906 vs Lucentis for diabetic vision swelling
This study compares two injectable medicines (BAT5906 and Lucentis) to treat diabetic macular edema—swelling in the back of the eye that blurs vision. Both drugs block a protein that causes abnormal blood vessel leakage, and this trial will show which works better.
Beijing, Beijing MunicipalityAges 18–80 - NCT07458061RecruitingPhase 1/Phase 2
Kamuvudine-9 for diabetic macular edema
This trial tests a new drug, Kamuvudine-9 (K9), to treat diabetic macular edema (swelling in the back of the eye caused by diabetes). It may help improve vision in people with diabetes who have not yet needed major treatments.
Roanoke, VirginiaAges 18 years+ - NCT07489131RecruitingPhase 3
Comparing a new macular edema treatment to Eylea HD
This study tests whether a new drug (AVT29) is as safe and effective as the standard treatment Eylea HD for people with diabetic macular edema (DME) — a condition where fluid builds up in the back of the eye due to diabetes. If you have vision loss from DME and haven't had anti-VEGF injections before, you may be able to join.
BudapestAges 18 years+ - NCT05885503RecruitingPhase 3
Testing an eye injection for diabetic macular swelling
This Phase 3 study compares a new eye injection (RC28-E) with the standard treatment (aflibercept) for diabetic macular edema, which is swelling in the central retina that affects vision. It aims to see whether the new treatment works as well and is safe.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06536491RecruitingPhase 1/Phase 2
EC-104 eye implant for diabetic macular edema
This early-phase trial tests a new implant (EC-104) that goes inside the eye to treat diabetic macular edema (DME), a condition that causes blurry vision from fluid buildup. The implant slowly releases medicine over time, and the study will see if it is safe and helpful for people with DME.
Tampa, FloridaAges 18 years+ - NCT07338097Enrolling by invitation
Comparing two eye injections for diabetic macular edema
This study tests whether one eye injection (aflibercept) works better than another (bevacizumab) for people with diabetic macular edema. Both are already used for this condition, and the goal is to see which provides better vision improvement.
Multan, Punjab ProvinceAges 30–60 - NCT04225611RecruitingPhase 1/Phase 2
Drug-delivering contact lens for recurrent macular swelling
This study tests a special contact lens that slowly delivers anti-inflammatory/steroid medicine to the back of the eye. It aims to treat cystoid macular edema that keeps coming back and may improve vision for people who respond to steroid treatment.
Boston, MassachusettsAges 18–85 - NCT03161652RecruitingPhase 2
Levosulpiride for diabetic eye swelling and retinopathy
This Phase 2 study tests whether levosulpiride can improve changes in the retina in people with diabetic retinopathy and diabetic macular edema (eye swelling that can affect vision). It may help by targeting chemicals in the body that could affect eye tissue and inflammation.
Querétaro City, QuerétaroAges 40–69 - NCT07449936RecruitingPhase 3
Comparing a new long-lasting injection to standard one for DME
This phase 3 trial tests a new long-acting injection (EYP-1901) against a standard one (aflibercept) for people with diabetic macular edema. Both treatments are given as eye injections, and the goal is to see if the new drug works as well and may require fewer injections.
Bakersfield, CaliforniaAges 18 years+ - NCT07449923RecruitingPhase 3
Comparing a new injection to standard treatment for diabetic macular edema
This trial compares a new treatment (EYP-1901, given as an injection) to a standard injection (aflibercept) for people with diabetic macular edema. It aims to see which works better at reducing swelling and improving vision.
Gilbert, ArizonaAges 18 years+ - NCT07425522RecruitingPhase 1
Testing a new eye injection for diabetic macular edema
This study tests a new drug (RO7823653) given as an eye injection for people with diabetic macular edema, a condition where swelling in the retina harms vision. It aims to see if the drug is safe and how the body processes it.
Peoria, ArizonaAges 18 years+ - NCT06942520RecruitingPhase 2
Gene therapy for diabetic macular edema in adults
This trial tests a gene therapy called RGX-314 for people with diabetic macular edema that affects the center of the vision. If you have had previous treatment and still have swelling, this study may be an option.
Reno, NevadaAges 25–89 - NCT07708142RecruitingPhase 3
Testing a new injection for swelling after retinal vein blockage
This trial tests a new medicine called SMO1 for people with vision loss and swelling in the eye caused by a blocked vein in the retina. It involves regular eye injections to see if the medicine can reduce swelling and improve vision.
Seoul, Gangdong-guAges 19 years+ - NCT06610747Recruiting
Home versus hospital care for diabetic eye swelling
This study tests whether receiving anti-VEGF injections for diabetic macular edema (DME) at home is as safe and effective as getting them in the hospital. You would use a home device to check your vision and eye scans, and a nurse would visit for injections.
Dongguan, GuangdongAges 18 years+
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Common questions
- Are there clinical trials for macular edema?
- Yes. Clin2 currently lists 53 recruiting macular edema studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a macular edema trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a macular edema trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.