Clinical trials
Macular Edema clinical trials
Below are recruiting macular edema clinical trials, each written for real people, not researchers. We’re tracking 53 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06962839RecruitingPhase 2
Study of BI 1815368 for diabetic macular edema
This trial tests an experimental medication (BI 1815368) given as an eye injection for people with diabetic macular edema, a condition where fluid builds up in the center of the retina and blurs vision. The study aims to see if this new treatment can reduce swelling and improve vision.
Phoenix, ArizonaAges 18 years+ - NCT06845163RecruitingPhase 2
Testing dapagliflozin for diabetic macular edema
This study tests whether a medication called dapagliflozin, which is usually used for diabetes and heart failure, can help reduce swelling in the retina (diabetic macular edema) and improve vision. It is for people with type 2 diabetes who are already taking insulin and metformin.
Alexandria, Alexandria GovernorateAges 18–85 - NCT06825702RecruitingPhase 2
Testing KIO-104 eye injection for macular edema
This trial tests an eye injection called KIO-104 to treat macular edema (swelling in the center of the retina) caused by conditions like uveitis, diabetes, or vein blockage. The goal is to see if it is safe and improves vision.
Sydney, New South WalesAges 18–85 - NCT06511700Enrolling by invitation
Nurse-led eye injections: a new care approach
This trial tests whether specially trained nurses can safely give eye injections instead of doctors. It may make treatment quicker and easier for people who need regular injections for eye conditions.
Sabadell, BarcelonaAges 18 years+ - NCT04187443RecruitingPhase 1
Drug MS-553 for diabetic eye swelling with reduced vision
This Phase 1 trial tests MS-553 to see how it works and how safely it can be given to people with diabetic retinopathy causing central macular swelling (macular edema). You may be considered if your vision and eye scan results match, and if you can follow frequent study visits.
Changsha, HunanAges 18 years+ - NCT05802329RecruitingPhase 1
Testing eye injections for diabetic macular swelling
This Phase 1 study tests the safety and early effectiveness of OCU200 eye injections in people with diabetic macular edema (DME) that affects the center of vision. It may help by reducing the eye swelling that blurs vision from diabetes.
Deerfield Beach, FloridaAges 18 years+ - NCT05916391RecruitingPhase 1
Gene therapy for diabetic macular swelling affecting vision
This early-stage (Phase 1) study tests a new gene therapy to improve vision for adults with diabetic macular edema. It mainly looks at whether the treatment can be safely given and may help your vision over time.
Tianjin, Tianjin,ChinaAges 18 years+ - NCT07812090RecruitingPhase 2
Oral medication for diabetic macular edema
This study tests an oral medication that may reduce swelling in the retina caused by diabetes. If you have diabetic macular edema affecting your central vision, this trial could help you preserve or improve your sight.
McAllen, TexasAges 18–75 - NCT07515079RecruitingPhase 3
Testing BAT5906 vs Lucentis for diabetic vision swelling
This study compares two injectable medicines (BAT5906 and Lucentis) to treat diabetic macular edema—swelling in the back of the eye that blurs vision. Both drugs block a protein that causes abnormal blood vessel leakage, and this trial will show which works better.
Beijing, Beijing MunicipalityAges 18–80 - NCT07489131RecruitingPhase 3
Comparing a new macular edema treatment to Eylea HD
This study tests whether a new drug (AVT29) is as safe and effective as the standard treatment Eylea HD for people with diabetic macular edema (DME) — a condition where fluid builds up in the back of the eye due to diabetes. If you have vision loss from DME and haven't had anti-VEGF injections before, you may be able to join.
BudapestAges 18 years+ - NCT07458061RecruitingPhase 1/Phase 2
Kamuvudine-9 for diabetic macular edema
This trial tests a new drug, Kamuvudine-9 (K9), to treat diabetic macular edema (swelling in the back of the eye caused by diabetes). It may help improve vision in people with diabetes who have not yet needed major treatments.
Roanoke, VirginiaAges 18 years+ - NCT07383701RecruitingPhase 2
Probiotic for diabetic macular edema
This trial tests whether a daily probiotic supplement (Lactiplantibacillus plantarum 299v) can help improve diabetic macular edema, a swelling in the back of the eye caused by diabetes. The goal is to see if adding this probiotic to your regular care could reduce swelling and protect your vision.
Boston, MassachusettsAges 18 years+ - NCT07338097Enrolling by invitation
Comparing two eye injections for diabetic macular edema
This study tests whether one eye injection (aflibercept) works better than another (bevacizumab) for people with diabetic macular edema. Both are already used for this condition, and the goal is to see which provides better vision improvement.
Multan, Punjab ProvinceAges 30–60 - NCT03161652RecruitingPhase 2
Levosulpiride for diabetic eye swelling and retinopathy
This Phase 2 study tests whether levosulpiride can improve changes in the retina in people with diabetic retinopathy and diabetic macular edema (eye swelling that can affect vision). It may help by targeting chemicals in the body that could affect eye tissue and inflammation.
Querétaro City, QuerétaroAges 40–69 - NCT04225611RecruitingPhase 1/Phase 2
Drug-delivering contact lens for recurrent macular swelling
This study tests a special contact lens that slowly delivers anti-inflammatory/steroid medicine to the back of the eye. It aims to treat cystoid macular edema that keeps coming back and may improve vision for people who respond to steroid treatment.
Boston, MassachusettsAges 18–85 - NCT07867080RecruitingPhase 3
Gene therapy injection for diabetic macular edema
This trial tests a one-time gene therapy injection into the eye for adults with diabetic macular edema (DME), a condition where fluid builds up in the retina and blurs vision. The goal is to reduce the need for frequent eye injections and help maintain vision over time.
Scottsdale, ArizonaAges 18 years+ - NCT07425522RecruitingPhase 1
Testing a new eye injection for diabetic macular edema
This study tests a new drug (RO7823653) given as an eye injection for people with diabetic macular edema, a condition where swelling in the retina harms vision. It aims to see if the drug is safe and how the body processes it.
Peoria, ArizonaAges 18 years+ - NCT07843849RecruitingPhase 4
Steroid treatment for diabetic macular edema
This study tests whether a steroid medication can help reduce swelling in the back of the eye caused by diabetic macular edema, a complication of type 2 diabetes. If you qualify, you may receive this treatment to potentially improve your vision.
Nashville, TennesseeAges 18 years+ - NCT06942520RecruitingPhase 2
Gene therapy for diabetic macular edema in adults
This trial tests a gene therapy called RGX-314 for people with diabetic macular edema that affects the center of the vision. If you have had previous treatment and still have swelling, this study may be an option.
Reno, NevadaAges 25–89 - NCT07708142RecruitingPhase 3
Testing a new injection for swelling after retinal vein blockage
This trial tests a new medicine called SMO1 for people with vision loss and swelling in the eye caused by a blocked vein in the retina. It involves regular eye injections to see if the medicine can reduce swelling and improve vision.
Seoul, Gangdong-guAges 19 years+ - NCT07705555RecruitingPhase 3
Comparing a new eye injection to standard treatment for diabetic eye swelling
This trial tests if a new medicine (MK-8748) works as well as or better than the usual treatment (aflibercept) for people with diabetic macular edema, a condition that causes vision loss from diabetes-related swelling in the back of the eye.
Glendale, CaliforniaAges 18 years+ - NCT07705607RecruitingPhase 3
Comparing MK-8748 to standard treatment for diabetic eye swelling
This trial tests a new medicine (MK-8748) against an existing treatment (aflibercept) for people with diabetic macular edema, which causes vision loss due to swelling in the back of the eye. The goal is to see which works better to improve or protect vision.
Winter Haven, FloridaAges 18 years+ - NCT06996080RecruitingPhase 3
Study of KSI-101 for swelling caused by eye inflammation
This trial tests a new medicine called KSI-101 given as an injection into the eye to treat swelling in the center of the retina caused by inflammation. It may help people whose vision has gotten worse due to this type of swelling.
Phoenix, ArizonaAges 18 years+ - NCT06990399RecruitingPhase 3
Testing KSI-101 eye injections for swelling from inflammation
This trial tests a new injected medicine (KSI-101) for people with swelling in the back of the eye caused by inflammation. The medicine is given directly into the eye to see if it can reduce the swelling and improve vision.
Phoenix, ArizonaAges 18 years+
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Common questions
- Are there clinical trials for macular edema?
- Yes. Clin2 currently lists 53 recruiting macular edema studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a macular edema trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a macular edema trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.