Clin2
NCT07705607Likely a fitNot yet recruiting

Comparing MK-8748 to standard treatment for diabetic eye swelling

Diabetic RetinopathyMacular Edema

Treatments studied

Part of Eyes & vision, Heart & circulation, Hormones & metabolism clinical trials.

This trial tests a new medicine (MK-8748) against an existing treatment (aflibercept) for people with diabetic macular edema, which causes vision loss due to swelling in the back of the eye. The goal is to see which works better to improve or protect vision.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
1,104 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have type 1 or type 2 diabetes with a recent blood sugar test (HbA1c) at 12% or lower.
  • Vision loss in one eye is mainly from diabetic macular edema (swelling in the back of the eye).
  • If you have not been treated for this eye condition before, your diagnosis must be within the last 9 months.
  • If you have had prior treatment, it must have started no more than 3 years ago.
  • You have no history of kidney failure requiring dialysis or transplant, and no recent stroke or heart attack (within 6 months).
  • You have not had cataract or glaucoma surgery in the study eye within the last 3 months.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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