Clinical trials
MCI clinical trials
Below are recruiting mci clinical trials, each written for real people, not researchers. We’re tracking 144 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07758660Enrolling by invitationPhase 2
Brain scan study for Alzheimer's research
This study uses brain scans (PET) to look at changes in the brain that may be related to memory problems or Alzheimer's disease. It aims to improve understanding of the disease and may help develop better treatments.
New York, New YorkAges 50 years+ - NCT05460468Recruiting
Brain stimulation study to improve memory in aging
This study tests a brain-stimulation approach to help improve memory as people age. You may be able to take part if you can consent and meet safety and medical criteria, especially related to brain/nerve health and seizure risk.
Durham, North CarolinaAges 18–75 - NCT07659964Recruiting
Rhythmic music and walking study for Alzheimer's
This study tests whether listening to a steady beat (rhythmic music) while walking can improve movement and brain function in people with mild Alzheimer's disease. Healthy volunteers are also needed for comparison.
Boston, MassachusettsAges 50–90 - NCT04956549Recruiting
Exercise program for early memory loss in African Americans
This study tests whether a structured exercise program can lower Alzheimer’s risk in older African American adults who have mild cognitive impairment (MCI). You’ll be placed by chance into an exercise group or a comparison group and attend group sessions for about a year.
Baton Rouge, LouisianaAges 60 years+ - NCT04582916RecruitingPhase 1
PET scan study of inflammation in major depression
This Phase 1 study uses a PET brain scan to look at inflammation-related activity (cyclooxygenase) in people with major depressive disorder (MDD). It may help researchers better understand how depression is connected to inflammation in the brain.
Bethesda, MarylandAges 18–70 - NCT06746909Recruiting
Brain inflammation and imaging in older adults at risk for dementia
This study looks at how changes in the brain (like inflammation) relate to thinking and memory decline in older adults. It uses brain scans and computer tools to find early signs of dementia risk, with the goal of better preventing memory loss.
PisaAges 65–89 - NCT06269939Recruiting
Memory training for healthy aging and mild memory loss
This study tests a special memory training program for people with mild memory problems (MCI) or healthy aging. It aims to improve how you learn and remember new information using guided methods.
East Hanover, New JerseyAges 60 years+ - NCT05697588Recruiting
Study blood and brain markers from mild memory loss to dementia
This study looks for “biomarkers” (measurable signs from blood and brain tests) that may help predict who with mild cognitive impairment (MCI) could later develop dementia. Results may help doctors spot risk earlier and better plan care.
Beijing, Beijing MunicipalityAges 50–85 - NCT06633978Recruiting
Digital tools for brain health in older adults
This study tests if using digital tools (like apps or computer programs) can improve memory, thinking, mood, stress, and sleep in healthy older adults. You will use the tools at home or in the lab, and researchers will track changes.
San Francisco, CaliforniaAges 60–85 - NCT07130669RecruitingPhase 1/Phase 2
Memory and thinking study for older adults
This trial tests a program to help maintain or improve memory and thinking skills in older adults. You may join if you are 60-89, speak English, and live at home or in an assisted-living facility.
Palo Alto, CaliforniaAges 60–89 - NCT07733726Enrolling by invitation
Dual-Task Mouth and Memory Training for Oral Frailty
This study tests a program that combines mouth exercises with memory tasks to see if it can improve both chewing, swallowing, and thinking skills in people who have oral frailty and some memory decline.
KowloonAges 50 years+ - NCT06601933RecruitingPhase 2
Computer thinking exercises for memory concerns in older adults
This study tests whether a computer-based thinking exercise program can improve memory and brain function in older adults with mild memory concerns. If you have age-related memory changes but not dementia, you may be able to join and get a free MRI scan.
Miami, FloridaAges 55–89 - NCT07731191Recruiting
Digital tools to predict Alzheimer's risk factors
This study uses smartphone tools to track early signs of Alzheimer's by analyzing risk factors. It is for people with mild cognitive issues (MCI) or subjective cognitive decline (SCD) who do not have dementia.
Brescia, BSAges 18 years+ - NCT07441122Recruiting
Brain game for focus: Using brain-computer tech in older adults
This study tests if a brain-computer interface can help older adults improve attention. You'll use a computer that reads your brain signals and gives feedback to train your focus.
Austin, TexasAges 18–90 - NCT06102486Recruiting
Speech in noise study for mild cognitive impairment
This study looks at how well people with mild cognitive impairment (MCI) understand speech in noisy settings. It aims to find better ways to diagnose and help people with thinking and memory concerns.
Lebanon, New HampshireAges 55–80 - NCT06670807Recruiting
Probiotic supplement for mild memory loss
This study tests whether a probiotic (a supplement with helpful bacteria) can help slow down memory and thinking problems in people with mild cognitive impairment (MCI). It is for adults aged 60–85 who have noticed their memory getting worse over time but can still handle daily activities.
Madrid, MadridAges 65–85 - NCT03402919Recruiting
Brain and memory study for people with thinking changes
This study looks at memory and thinking changes using questionnaires, memory testing, and brain scans. It may help researchers better understand neurodegeneration and dementia and how these problems show up over time.
Calgary, AlbertaAges 50–90 - NCT03653156Recruiting
Aging and brain study for mild memory loss and dementia
This study checks how age affects memory and thinking, and compares people with mild memory problems, Alzheimer’s disease types, vascular dementia, and healthy controls. You may help researchers understand brain changes using thinking tests, MRI scans, and blood or spinal fluid tests.
Hefei, AnhuiAges 18 years+ - NCT07701785Recruiting
Brain stimulation study for Parkinson's with mild memory issues
This trial tests a type of brain stimulation called iTBS on an area of the brain that may help with thinking and memory problems in people with Parkinson's disease and mild cognitive impairment. If you qualify, you and your caregiver would take part in sessions and answer questions about your daily life.
Charleston, South CarolinaAges 50–85 - NCT04360200Recruiting
Study of thinking changes in older adults
This trial looks at people over age 50 who have mild thinking or memory problems but do not have dementia by standard clinical criteria. It tests how these early changes are characterized and measured using exams such as blood tests and brain scans, which may help improve understanding and future care.
Guangzhou, GuangdongAges 50 years+ - NCT04525144RecruitingPhase 2
Test EGb 761 for mild memory loss with brain blood vessel disease
This trial studies EGb 761 to see if it can improve symptoms in people with mild cognitive impairment (early memory/thinking changes) who also have signs of brain blood vessel disease. It may help by targeting the brain changes seen on scans.
SingaporeAges 45–85 - NCT04906863Recruiting
Genetic study for early dementia in adults and families
This trial studies genes to better understand why some people develop dementia and memory problems earlier in life. It may help researchers find clearer causes and improve future testing and treatments for families affected by dementia.
New York, New YorkAges 35 years+ - NCT04765137RecruitingPhase 2
Atorvastatin to improve brain blood flow in mild memory decline
This Phase 2 study tests whether the cholesterol medicine atorvastatin can improve how well blood vessels in the brain respond in people with mild cognitive impairment (MCI). It may help brain circulation and possibly slow thinking and memory problems.
Baltimore, MarylandAges 60–95 - NCT07698899RecruitingPhase 1
Study of a new treatment for childhood brain and CNS cancers
This trial tests a radioactive drug (177Lu-DTPA-Omburtamab) given directly into the fluid around the brain for children and teens with certain brain cancers or cancers that have spread to the central nervous system. It aims to see if this treatment is safe and effective for tumors that have come back or not responded to other therapies.
Basking Ridge, New JerseyAges 3–22
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Common questions
- Are there clinical trials for mci?
- Yes. Clin2 currently lists 144 recruiting mci studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mci trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mci trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.