Clinical trials
Mental Disorder clinical trials
Below are recruiting mental disorder clinical trials, each written for real people, not researchers. We’re tracking 348 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06897553Recruiting
ACT for Better Mental Health with Neurologic Illness
This study tests a type of talk therapy (ACT) to help people with neurological conditions like Parkinson’s, MS, or epilepsy feel better emotionally. It's for those who are struggling with depression, anxiety, or stress and are ready to work on their mental health.
BielefeldAges 18 years+ - NCT04289142RecruitingPhase 4
Testing memory effects of dexmedetomidine during heart surgery
This study looks at how a sleep medicine called dexmedetomidine affects thinking and memory after heart surgery. It compares cognitive outcomes over time to see if this sedation choice changes long-term brain function.
Vancouver, British ColumbiaAges 60 years+ - NCT05886114Recruiting
Lifestyle program to help older adults at risk of memory decline
This trial tests a multi-part lifestyle program to help older adults who may be starting to decline in thinking and memory. It may help slow cognitive decline by combining lifestyle changes over 24 months.
Hangzhou, ZhejiangAges 60–80 - NCT07010614Recruiting
Brain stimulation for memory in schizophrenia
This trial uses brain stimulation to target memory areas in people with schizophrenia or related conditions. It aims to see if this can help improve symptoms.
Stanford, CaliforniaAges 18–65 - NCT06548490RecruitingPhase 2
Semaglutide for Opioid Use Disorder
This study tests whether a once-weekly injection of semaglutide (a GLP-1 receptor agonist) can reduce opioid use in people who are already on buprenorphine or methadone but still using opioids. It lasts about 19 weeks.
Baltimore, MarylandAges 18–75 - NCT06878859Recruiting
Online program for depression and cannabis use
This study tests a digital (online) program designed to help people who struggle with both depression and cannabis use. If you're feeling down and also using cannabis more than you'd like, this program might help you manage both.
Boston, MassachusettsAges 18 years+ - NCT07742722Recruiting
Peer support for veterans with mental health and substance use issues
This study tests a program where trained peer supporters help veterans who have been involved with the justice system and have mental health or substance use issues. It aims to improve their well-being and recovery.
Bedford, MassachusettsAges 18 years+ - NCT06511713Recruiting
AI eye test for early warning of mental disorders
This trial uses advanced eye-tracking and imaging of the back of your eye to find early warning signs for mental health conditions. It may help doctors detect problems sooner, so you can get help faster.
Shanghai, Shanghai MunicipalityAges 15–45 - NCT06914622Recruiting
Real-life recovery study for mental health
This study uses a smartphone app to track daily experiences, physical activity, and biological markers in people receiving treatment for a mental disorder. The goal is to understand how these factors relate to personal recovery.
BresciaAges 18 years+ - NCT06567145Recruiting
Group therapy for self-stigma in mental health
This study tests a group therapy program designed to help people with mental health conditions reduce the shame and stigma they feel about their illness. It takes place in northeastern Italy and is for people who are stable on their current medications.
VeronaAges 18 years+ - NCT06722781Recruiting
Online group therapy for common mental health conditions
This trial tests an online group therapy for people waiting for high intensity CBT. It aims to provide quicker support for conditions like depression, anxiety, and PTSD.
Doncaster, South YorkshireAges 17 years+ - NCT06433271Recruiting
Therapy study for adjustment disorder after trauma
This study compares a new type of talk therapy (Transdiagnostic Behavior Therapy) to standard care for veterans and active military members who are struggling with adjustment disorder after a traumatic event. The goal is to see which approach helps people feel better and adjust to life after trauma.
Charleston, South CarolinaAges 18 years+ - NCT07286305Recruiting
Media and Mental Health Study for Adults
This study looks at how media affects mental health. If you're an adult English speaker who has been treated at WHC for at least 6 months and are not currently in crisis or dependent on substances, you may be able to join.
Tucson, ArizonaAges 18 years+ - NCT06702410Recruiting
Improving child mental health services with teacher training
This study tests a training program called mhGAP for kindergarten teachers and healthcare workers to help children ages 2–6 who may have mental or behavioral challenges. The goal is to improve support and services for these children in Zhongshan City, China.
Zhongshan, GuangdongAges 2–6 - NCT05138614Recruiting
Help for people with opioid use disorder and mental health needs
This trial studies a program meant to improve treatment access and support recovery for people with opioid use disorder who also have mental health symptoms. It may help if you are new to the program or recently relapsed, or if mental health symptoms have worsened—even without a relapse.
Holyoke, MassachusettsAges 18 years+ - NCT07239843Enrolling by invitation
Study of blood markers and mental health in brain diseases
This study looks at how social factors and blood markers relate to psychiatric symptoms in people with brain diseases or mental disorders. It aims to find new ways to understand and diagnose these conditions.
Barcelona, BarcelonaAges 18 years+ - NCT05525962Recruiting
Study factors that affect development in foster children
This study looks at how different stress and support factors may influence how children and teens grow and cope while they are involved with child protective services. It may help clinicians understand what supports work best for children in care.
CanteleuAges Up to 16 years - NCT05674617Recruiting
PTSD treatment for Veterans with serious mental illness
This trial tests a PTSD treatment approach for Veterans who also have a serious mental illness, aiming to improve day-to-day functioning. It includes Veterans who receive outpatient mental health care through the VA and have confirmed PTSD in the last month.
Baltimore, MarylandAges 18 years+ - NCT06454695Recruiting
Treating depression by reducing negative future images
This study tests a new way to treat major depression by helping people change distressing mental pictures they have about the future. It might be a good fit if you have a few specific negative images that bother you.
Amsterdam, North HollandAges 18 years+ - NCT06673966Recruiting
Schizophrenia brain and immune health study
This study looks at how immune system health relates to brain changes in people with schizophrenia. It uses brain imaging and electrical activity tests to understand these connections.
Changsha, HunanAges Any age - NCT05074901Recruiting
Using a health app in France with virtual support
This trial tests whether a digital health app (with “virtual agents,” like guided prompts/support) can improve people’s health outcomes. You may help the study by using the app and completing its questionnaires.
BordeauxAges 18 years+ - NCT06088121Recruiting
TMS with cognitive training for mild Alzheimer's dementia
This study tests a combination of brain stimulation (TMS) and cognitive training to improve memory and thinking in people with mild Alzheimer's. It may help if you are already on a stable dose of a donepezil-type medication and have a confirmed Alzheimer's diagnosis.
Incheon, Bupyeong 6(yuk)-dong, Bupyeong-guAges 60–85 - NCT06930547Recruiting
Smoking cessation education for recovery
This study tests whether education classes can help people who are in recovery from mental health issues quit smoking. It is for people registered with a Community Mental Health Center who smoke daily.
Erzurum, ErzurumAges 18 years+ - NCT07281729Enrolling by invitation
Suicide risk factors study for mood disorders
This study looks at why some people with mood disorders (like depression or bipolar disorder) think about or attempt suicide. By finding the risk factors, doctors hope to better prevent suicide. The study involves filling out questionnaires.
Shanghai, Shanghai MunicipalityAges 16–60
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Common questions
- Are there clinical trials for mental disorder?
- Yes. Clin2 currently lists 348 recruiting mental disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mental disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mental disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.