Clinical trials
Mental Health Impairment clinical trials
Below are recruiting mental health impairment clinical trials, each written for real people, not researchers. We’re tracking 182 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06508450Recruiting
Mental health support for minority young adults
This trial tests a program to help racial and ethnic minority young adults engage with mental health services. It aims to improve access and participation in care.
The Bronx, New YorkAges 18–34 - NCT06512220RecruitingPhase 2
Psilocybin for treatment-resistant depression brain imaging study
This study tests whether a psilocybin-based treatment can help people with depression that has not improved after trying several antidepressants. You will receive the study treatment and have brain scans to see how it affects brain connections.
Toronto, OntarioAges 18–65 - NCT06528938Recruiting
Accelerated vs. standard TMS for teen depression
This study tests whether a faster, brain-guided form of TMS (called iTBS) can help treat depression in teenagers better than standard TMS. You may qualify if you're 16–19, have tried an antidepressant that didn't work well, and have no medical reasons to avoid TMS or MRI.
Ottawa, OntarioAges 16–19 - NCT06548126Recruiting
Online parenting program for displaced families
This trial tests an online parenting program for caregivers who have experienced forced displacement. It aims to support families with children aged 6 to 12 by teaching positive parenting skills.
Tempe, ArizonaAges 18 years+ - NCT06582784Recruiting
Using a phone app to help cancer survivors with depression
This study tests a mobile app to help cancer survivors who are feeling depressed. If you have a smartphone and are willing to use an app for mood support, you may be able to join.
Charleston, South CarolinaAges 18 years+ - NCT06597474RecruitingPhase 2/Phase 3
Food-Body-Mind wellness program for preschoolers
This study tests a 16-week program called Food-Body-Mind that helps preschoolers and their families build healthy habits. It focuses on movement, eating well, and feeling good about your body, and is designed for children ages 3 to 5 in Head Start programs.
Jackson, MichiganAges 3–5 - NCT06626789RecruitingPhase 1/Phase 2
Brain training to help control emotions in BPD
This study tests whether a brain-training technique (using fMRI to help you learn to control your emotions) can help people with borderline personality disorder who haven't improved with other therapies.
Freiburg im BreisgauAges 18–65 - NCT06672588Recruiting
Magnetic seizure therapy for schizophrenia
This trial tests a new type of brain stimulation called magnetic seizure therapy (MST) for people with schizophrenia who haven't gotten better with standard medicines. The goal is to see if MST can help reduce symptoms like hallucinations or confusion.
Vancouver, British ColumbiaAges 18 years+ - NCT06389565Recruiting
Change My Story: A mental health program for young adults with HIV
This study tests a mental health program to help young people living with HIV who feel down or depressed. It's designed to see if talking through your story can help you feel better and function day-to-day.
Ibadan, Oyo StateAges 16–29 - NCT06732128Recruiting
Nature virtual reality for depression in Alzheimer's disease
This trial tests whether a virtual reality nature experience can help improve mood in people with early-to-moderate Alzheimer's disease. Participants will use a VR headset and a few apps at home, with a caregiver present, over several sessions.
Toronto, OntarioAges 50 years+ - NCT06776523Recruiting
Psychological help study for refugees in Switzerland
This study tests a brief psychological program (Problem Management Plus, or PM+) to see if it helps refugees and asylum seekers feel better. If you are feeling stressed, anxious, or down, this may be an option for you.
ZurichAges 16 years+ - NCT06782321Recruiting
Virtual emotional support after stroke
This study tests a virtual program to help with emotional recovery like anxiety or sadness after a stroke. You can join from home using your own device.
Charleston, South CarolinaAges 21 years+ - NCT06788886Recruiting
Breathing practice for brain and mental health in cancer and other illnesses
This study tests a simple breathing practice to see if it can improve brain health and mental well-being for people with cancer, multiple sclerosis, or their caregivers. You will do light exercises and answer questionnaires, and some participants will also have an MRI brain scan.
Rochester, MinnesotaAges 18–85 - NCT06798324RecruitingPhase 4
Brain stimulation plus smoking cessation medication for quitting smoking
This trial tests whether combining brain stimulation (tDCS) with a smoking cessation medication (varenicline) helps people quit smoking. You would attend daily visits for two weeks.
Toronto, OntarioAges 18–85 - NCT06854367Recruiting
Comparing fast vs. standard brain stimulation for depression in older adults
This study tests if a faster form of brain stimulation (accelerated theta burst stimulation) works as well as the standard version for treating depression in adults 60 and older. It may help those who haven't gotten relief from antidepressant medications.
Toronto, OntarioAges 60 years+ - NCT06888726Recruiting
Brain stimulation for negative symptoms in schizophrenia
This trial tests if a gentle electric current applied to your head can help with negative symptoms (like lack of motivation or emotion). You must have schizophrenia, take a common antipsychotic, and have some ongoing negative symptoms.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06891300RecruitingPhase 2/Phase 3
Ketamine for Suicidal Thoughts in Depression
This study tests if ketamine can help reduce suicidal thoughts in people with major depression. You'll receive ketamine treatment and be monitored closely.
Ottawa, OntarioAges 18–65 - NCT06920628RecruitingPhase 1
Brain scan study for long COVID neurological symptoms
This study uses a special PET scan to look at brain inflammation in people with neurological symptoms after COVID-19. It aims to understand how inflammation might be linked to ongoing problems like brain fog or memory issues.
Bethesda, MarylandAges 18–70 - NCT06939712Recruiting
Online mental health program for Crohn's patients
This study tests an online program that uses positive psychology to help improve mental health and quality of life in people with Crohn's disease who have mild anxiety or depression. The program is done over the internet, so you can join from home.
Hangzhou, ZhejiangAges 18–75 - NCT06942858Recruiting
Boosting therapy for anorexia with brain stimulation
This trial tests whether a non-invasive brain stimulation technique called deep transcranial magnetic stimulation (dTMS) can help cognitive-behavioral therapy work better for people with anorexia nervosa. It aims to improve outcomes by targeting brain areas linked to thinking and behavior.
Shanghai, Shanghai MunicipalityAges 18–35 - NCT06959342Recruiting
Brain stimulation to reduce cravings in alcohol use disorder
This trial tests if a gentle brain stimulation technique (tDCS) can help people with alcohol use disorder control their cravings and drinking habits. It is an add-on to your regular treatment.
MannheimAges 18–65 - NCT07127159Recruiting
Music listening for stroke recovery
This study tests whether listening to music at home can help with mood and thinking after a stroke. You'll be asked to listen to music or audio stories for 30 minutes a day, and we'll use MRI scans to see how your brain responds.
New York, New YorkAges 50–90 - NCT07183748RecruitingPhase 2
Psilocybin microdosing plus therapy for hard-to-treat depression
This trial tests whether taking very small, repeated doses of psilocybin (a substance found in magic mushrooms) along with talk therapy can help people with depression that hasn't gotten better with other treatments. You'll need to stop your current depression medications and avoid drugs or alcohol for the study period.
BeershebaAges 18–65 - NCT07198594Recruiting
Fast brain stimulation for hard-to-treat OCD
This study tests a fast-acting brain stimulation method (accelerated rTMS) for people whose obsessive-compulsive disorder has not improved enough with standard treatments. It aims to help those who still have moderate to severe symptoms despite trying multiple medications.
Shanghai, Shanghai MunicipalityAges 18–60
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Common questions
- Are there clinical trials for mental health impairment?
- Yes. Clin2 currently lists 182 recruiting mental health impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mental health impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mental health impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.