Clinical trials
Mental Health Impairment clinical trials
Below are recruiting mental health impairment clinical trials, each written for real people, not researchers. We’re tracking 179 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07183748RecruitingPhase 2
Psilocybin microdosing plus therapy for hard-to-treat depression
This trial tests whether taking very small, repeated doses of psilocybin (a substance found in magic mushrooms) along with talk therapy can help people with depression that hasn't gotten better with other treatments. You'll need to stop your current depression medications and avoid drugs or alcohol for the study period.
BeershebaAges 18–65 - NCT07178561Recruiting
Exercise for older adults with chronic back pain and anxiety
This study tests whether a supervised exercise program can reduce disability and improve mental health in older adults with chronic low back pain, poor sleep, and mild to moderate anxiety or depression.
Gaza, Gaza StripAges 55–70 - NCT07165964Recruiting
Nurse support for women's mental health during menopause
This study tests whether extra support from a nurse can help women going through menopause feel better emotionally and take better care of themselves. If you are between 42 and 58 and have symptoms like hot flashes or mood swings, you may be able to join.
L'Hospitalet de Llobregat, BarcelonaAges 42–58 - NCT07173608Recruiting
Meditation and thinking skills for teen mental health
This study tests whether learning meditation and a thinking skill called cognitive reappraisal (changing how you think about a situation) can help teens feel better and handle stress. It is for teens aged 15-18 who live in the US and can visit a hospital in Boston.
Boston, MassachusettsAges 15–18 - NCT07127159Recruiting
Music listening for stroke recovery
This study tests whether listening to music at home can help with mood and thinking after a stroke. You'll be asked to listen to music or audio stories for 30 minutes a day, and we'll use MRI scans to see how your brain responds.
New York, New YorkAges 50–90 - NCT07118072Recruiting
Online therapy for childhood trauma and depression symptoms
This study will test if a special online therapy program, called i-STAIR, can help people who had a tough childhood and are now dealing with some depression symptoms. It focuses on building skills to manage emotions and relationships, all from the comfort of your home.
SingaporeAges 21–65 - NCT06942858Recruiting
Boosting therapy for anorexia with brain stimulation
This trial tests whether a non-invasive brain stimulation technique called deep transcranial magnetic stimulation (dTMS) can help cognitive-behavioral therapy work better for people with anorexia nervosa. It aims to improve outcomes by targeting brain areas linked to thinking and behavior.
Shanghai, Shanghai MunicipalityAges 18–35 - NCT07109245RecruitingPhase 4
Do antipsychotics block insulin action in the brain?
This study tests whether a single dose of a common antipsychotic medication affects how the brain responds to insulin, which could help explain weight gain and metabolic side effects. Healthy young adults will receive either the antipsychotic or a placebo, then have their brain activity measured with an MRI.
Toronto, OntarioAges 18–35 - NCT07055061Recruiting
Music for reducing stress, anxiety and depression
This trial tests if listening to specially designed music can help reduce stress, anxiety and depression. It may be a good option for people who are not currently taking medication or receiving treatment.
Beijing, Beijing MunicipalityAges 18–60 - NCT07060690Recruiting
Online support program for depressed women
This trial tests a personalized online program with human support to see if it can help women with depression and possibly improve mental health and biological markers. It might be an option if you are a woman with moderate depression and you are comfortable using digital devices.
Barcelona, BarcelonaAges 18–45 - NCT06888726Recruiting
Brain stimulation for negative symptoms in schizophrenia
This trial tests if a gentle electric current applied to your head can help with negative symptoms (like lack of motivation or emotion). You must have schizophrenia, take a common antipsychotic, and have some ongoing negative symptoms.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06959342Recruiting
Brain stimulation to reduce cravings in alcohol use disorder
This trial tests if a gentle brain stimulation technique (tDCS) can help people with alcohol use disorder control their cravings and drinking habits. It is an add-on to your regular treatment.
MannheimAges 18–65 - NCT06963554Recruiting
Does Project Support help families after trauma?
This study tests a program called Project Support to help families deal with trauma. If you're a caregiver looking for trauma services for your 6-to-13-year-old child, and you can do telehealth sessions, this may be a good fit.
Charleston, South CarolinaAges 6–13 - NCT06939712Recruiting
Online mental health program for Crohn's patients
This study tests an online program that uses positive psychology to help improve mental health and quality of life in people with Crohn's disease who have mild anxiety or depression. The program is done over the internet, so you can join from home.
Hangzhou, ZhejiangAges 18–75 - NCT06941831Recruiting
Early childhood development program in Rwanda
This study looks at a program that helps families with young children (birth to 3 years) in Rwanda. It tests how well a digital dashboard supports caregivers and community workers who deliver early childhood development activities.
Kigali, KigaliAges 18 years+ - NCT06920628RecruitingPhase 1
Brain scan study for long COVID neurological symptoms
This study uses a special PET scan to look at brain inflammation in people with neurological symptoms after COVID-19. It aims to understand how inflammation might be linked to ongoing problems like brain fog or memory issues.
Bethesda, MarylandAges 18–70 - NCT06891300RecruitingPhase 2/Phase 3
Ketamine for Suicidal Thoughts in Depression
This study tests if ketamine can help reduce suicidal thoughts in people with major depression. You'll receive ketamine treatment and be monitored closely.
Ottawa, OntarioAges 18–65 - NCT06854367Recruiting
Comparing fast vs. standard brain stimulation for depression in older adults
This study tests if a faster form of brain stimulation (accelerated theta burst stimulation) works as well as the standard version for treating depression in adults 60 and older. It may help those who haven't gotten relief from antidepressant medications.
Toronto, OntarioAges 60 years+ - NCT05012072Recruiting
Lifestyle coaching to lower pregnancy stress and risk
This study tests a lifestyle coaching program to help reduce stress and improve emotional wellbeing during pregnancy. It may help lower risks for the baby by supporting healthier daily routines and mental health.
Webster, TexasAges 18–45 - NCT06798324RecruitingPhase 4
Brain stimulation plus smoking cessation medication for quitting smoking
This trial tests whether combining brain stimulation (tDCS) with a smoking cessation medication (varenicline) helps people quit smoking. You would attend daily visits for two weeks.
Toronto, OntarioAges 18–85 - NCT06792175Enrolling by invitation
Using speech to detect mental health conditions
This study uses a computer program to listen to your speech and see if it can help detect mental health or neurodevelopmental conditions. It may help find new ways to diagnose conditions like ADHD, anxiety, depression, and others earlier.
Brookline, MassachusettsAges 13–60 - NCT06782321Recruiting
Virtual emotional support after stroke
This study tests a virtual program to help with emotional recovery like anxiety or sadness after a stroke. You can join from home using your own device.
Charleston, South CarolinaAges 21 years+ - NCT06788886Recruiting
Breathing practice for brain and mental health in cancer and other illnesses
This study tests a simple breathing practice to see if it can improve brain health and mental well-being for people with cancer, multiple sclerosis, or their caregivers. You will do light exercises and answer questionnaires, and some participants will also have an MRI brain scan.
Rochester, MinnesotaAges 18–85 - NCT06776523Recruiting
Psychological help study for refugees in Switzerland
This study tests a brief psychological program (Problem Management Plus, or PM+) to see if it helps refugees and asylum seekers feel better. If you are feeling stressed, anxious, or down, this may be an option for you.
ZurichAges 16 years+
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Common questions
- Are there clinical trials for mental health impairment?
- Yes. Clin2 currently lists 179 recruiting mental health impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mental health impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mental health impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.