Clinical trials
Mental Health Impairment clinical trials
Below are recruiting mental health impairment clinical trials, each written for real people, not researchers. We’re tracking 182 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07214415RecruitingPhase 2
Hyperbaric oxygen therapy for veterans with brain injury or mental health issues
This trial tests whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can improve thinking, mood, and quality of life in veterans with mild traumatic brain injury, PTSD, anxiety, or depression. You must have already tried at least one evidence-based therapy like CBT or EMDR.
Boise, IdahoAges 18–75 - NCT07228182Recruiting
Brain stimulation study for gambling disorder
This trial tests a non-invasive brain stimulation method called high-intensity transcranial alternating current stimulation to see if it can reduce gambling urges and behavior in people with gambling disorder.
ShanghaiAges 18–60 - NCT07682064Recruiting
Group therapy for emotional disorders in adults
This trial tests a group therapy program for adults with emotional disorders like depression or anxiety. It is designed to help you manage difficult emotions and improve your well-being.
Logroño, La RiojaAges 18–65 - NCT07305688Recruiting
Climate anxiety and suicide risk in young people
This study explores how climate anxiety affects young people who are at risk for suicide. It aims to better understand the link between worries about climate change and suicidal thoughts or behaviors.
LimogesAges 16–24 - NCT07342907Recruiting
Internal Family Systems therapy for borderline personality disorder
This study tests a type of talk therapy called Internal Family Systems (IFS) to see if it helps people with borderline personality disorder (BPD). You would attend 50 therapy sessions over about 12-15 months to explore how this approach may improve your symptoms and well-being.
Tiny, OntarioAges 18 years+ - NCT07364799Recruiting
Sound therapy for stress in detained teens
This trial tests a multi-sensory therapy called SoundHeal for teens in juvenile detention. It uses sound and vibration to help with stress, anxiety, depression, or substance use.
San Luis Obispo, CaliforniaAges 12–18 - NCT07369752Recruiting
Breathing exercises for teens with depression or anxiety
This study looks at whether breathing exercises can help improve brain health and mental well-being in teens with depression or anxiety. It is designed for adolescents who are already receiving care at a Mayo Clinic psychiatry clinic.
Albert Lea, MinnesotaAges 12–17 - NCT00025935Recruiting
Brain Function Studies in Youth With Mood and Attention Disorders
This research study examines how the brains of children and teenagers with mood problems (like persistent irritability or depression) or attention difficulties work differently. Researchers use brain scans and tasks to understand these conditions better and track changes as young people grow up.
Bethesda, MarylandAges 7–60 - NCT02543983RecruitingPhase 2
Brain scan and ketamine study for suicidal thoughts
This trial studies how ketamine affects the brain in people dealing with suicidal thoughts or an active suicide crisis. It uses questionnaires, consent testing, and brain imaging to look for biological changes that may relate to symptom improvement.
Bethesda, MarylandAges 18–70 - NCT07444879Recruiting
Blood markers in panic disorder
This study looks at certain blood markers (IL-33, sST2, and CRP) in people with panic disorder to see if they are different from healthy individuals. It may help researchers understand more about panic disorder.
Elâzığ, ElâzığAges 18–65 - NCT07673380RecruitingPhase 2
Mobile health for opioid recovery and mental health
This study uses a mobile health app to help Black and African American individuals recover from opioid or stimulant use and improve mental health. It aims to see if the app can support treatment and well-being.
St Louis, MissouriAges 18 years+ - NCT07615257Recruiting
Mindfulness and CBT for Psoriasis-Related Emotional Stress
This study tests whether a combination of mindfulness and cognitive behavioral therapy (CBT)—talk-based techniques to manage thoughts and emotions—can help psoriasis patients feel less stressed and more compassionate toward themselves. Participants attend sessions over several weeks to learn these skills.
Rahim Yar Khan, Punjab ProvinceAges 25–75 - NCT07262580Enrolling by invitation
Finding meaning in cardiac rehab: a study
This study tests a program to help people in cardiac rehabilitation find personal meaning and purpose. It explores if the program works in individual, group, or paired sessions with a relative.
Odense, Region SyddanmarkAges 18 years+ - NCT06792175Enrolling by invitation
Using speech to detect mental health conditions
This study uses a computer program to listen to your speech and see if it can help detect mental health or neurodevelopmental conditions. It may help find new ways to diagnose conditions like ADHD, anxiety, depression, and others earlier.
Brookline, MassachusettsAges 13–60 - NCT06648928Enrolling by invitation
App for reducing PTSD in Florida 9/11 responders
This study is testing a mobile app called PTSD Coach, along with support from a clinician, to help World Trade Center responders in Florida reduce symptoms of post-traumatic stress. It may be a good fit if you have some PTSD symptoms but not severe alcohol or drug use, and you are not already receiving PTSD treatment.
Miami, FloridaAges Any age - NCT07085923Recruiting
Heart health study for people with mental illness
This study tests a program to improve heart health in people with schizophrenia or bipolar disorder who take antipsychotic medication or lithium and have a high body weight. The goal is to help reduce heart disease risk.
OsloAges 25–70 - NCT07278440Recruiting
Exercise program for brain tumor patients and their partners
This study tests if a home exercise program can improve mental and physical health for people with brain tumors and their live-in partners. Both of you will be guided through exercise sessions together over video.
Portland, OregonAges 18 years+ - NCT07754929Recruiting
Digital support for prostate cancer survivors' sexual and mental health
This study tests a smartphone-based program designed to help prostate cancer survivors improve their mental and sexual health. It may offer a convenient way to get support without visiting a clinic.
PortoAges 18 years+ - NCT06050603Recruiting
MRI guided brain stimulation study for memory
This study tests a new way to use brain stimulation guided by MRI to understand memory. It may help people with mild memory problems or healthy volunteers.
Toronto, OntarioAges 18–80 - NCT05362292RecruitingPhase 4
Treating bladder leakage to support mind and body health
This study tests medicines to reduce “urgency” urine leakage (when you suddenly feel you must go) and to see whether improving bladder control also helps overall mental and physical health. You may be eligible if you have had these symptoms for at least 3 months and can follow the study plan.
Palo Alto, CaliforniaAges 60 years+ - NCT05544344Recruiting
Program to improve health and daily functioning in adults
This trial studies a supportive “re-start” program to help adults with serious mental health conditions improve health and daily functioning. If you can join online sessions and meet the other requirements, you may be able to participate and see whether this program helps.
Chicago, IllinoisAges 18 years+ - NCT06174038Recruiting
Hearing aids for memory and hearing loss study
This study tests whether hearing aids can help people with both hearing loss and early memory problems. It lasts for a period of time, and you will be asked to wear hearing aids daily.
New York, New YorkAges 55–75 - NCT07672938Recruiting
Olive supplement and Mediterranean diet for mild memory loss
This trial tests whether a dietary supplement made from olive polyphenols, combined with following a Mediterranean diet, can help protect thinking and memory in people with mild cognitive impairment (MCI). It may be a good fit if you have early memory changes and want to try a nutrition-based approach.
Thessaloniki, Central MacedoniaAges 50–85 - NCT07581171Recruiting
Intergenerational Mentoring Program for Youth and Older Adults
This study brings together older adults and young people (ages 12–21) whose parents have mental health challenges. The goal is to create supportive friendships between generations and reduce loneliness and isolation for both groups.
HamburgAges 12 years+
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Common questions
- Are there clinical trials for mental health impairment?
- Yes. Clin2 currently lists 182 recruiting mental health impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mental health impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mental health impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.