Clinical trials
Mental Health clinical trials
Below are recruiting mental health clinical trials, each written for real people, not researchers. We’re tracking 725 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07379138Recruiting
Talk therapy for distress in advanced melanoma
This study is testing whether a type of talk therapy (cognitive behavioral therapy) can help improve quality of life, including mental health, for people recently diagnosed with advanced melanoma. It is designed to understand and reduce cancer-related distress.
Rochester, MinnesotaAges 18 years+ - NCT03987633Recruiting
Study links health records and samples to understand health gaps
This study asks people affected by a specific illness (or their family member) to share saliva (and sometimes blood) and answer health and quality-of-life questions. The goal is to better understand and reduce health inequality by matching new information with medical records.
Wolverhampton, West MidlandsAges 6 years+ - NCT06377189Recruiting
Mental health support from a specialist in primary care
This study tests whether adding a psychiatric consultant to your primary care team can help people struggling with mental distress or complex medical issues. If you're already seeing a primary care doctor and need extra mental health support, this might be for you.
Neuchâtel, Canton of NeuchâtelAges 18 years+ - NCT07169630RecruitingPhase 1
PET scan study for Alzheimer's or mild cognitive impairment
This study uses a special PET scan to look at a brain protein called PDE4 in people with Alzheimer's disease or mild cognitive impairment. It may help researchers understand how this protein is involved in memory and thinking problems.
Bethesda, MarylandAges 50–100 - NCT07658898Recruiting
Brain stimulation for negative and cognitive symptoms in schizophrenia
This study tests a new type of brain stimulation called temporal interference to see if it can help with negative symptoms (like lack of motivation or emotion) and cognitive symptoms (like trouble with memory or focus) in schizophrenia. It uses a special head device to target a specific brain area.
ShanghaiAges 18–65 - NCT00271622Recruiting
Screening test for child or adult brain and behavior patterns
This study uses a structured check-up to learn about how someone’s thinking, behavior, and development may differ from typical patterns. It involves an interview and possibly medical, nervous-system, and blood or urine tests to understand what kinds of issues might be present.
Bethesda, MarylandAges 1 month+ - NCT07686393RecruitingPhase 1
Pet scan study of brain chemical norepinephrine
This study uses a special PET scan to look at the brain chemical norepinephrine, which may be linked to mood and anxiety. It helps researchers understand how the brain works by taking detailed pictures.
Bethesda, MarylandAges 18–105 - NCT04950309Recruiting
Brain-signal scanning study using a new MEG sensor
This study tests and “maps” brain activity using a special brain-scanning sensor system that measures tiny magnetic signals. It may help researchers improve how brain function is measured for future studies.
Bethesda, MarylandAges 18–65 - NCT06626789RecruitingPhase 1/Phase 2
Brain signal training to help regulate emotions
This study tests a new brain-training technique that may help people with borderline personality disorder manage their emotions better. You will do mental exercises while an MRI scans your brain, and the results will show whether this training can reduce emotional distress.
Freiburg im BreisgauAges 18–65 - NCT06849869Recruiting
Collaborative care for perinatal wellness
This trial tests a collaborative care model to support the mental health and wellness of pregnant and postpartum people. It aims to improve access to care and outcomes for all patients at participating clinics.
Providence, Rhode IslandAges 18 years+ - NCT05669703Recruiting
Tracking mood and activity patterns in bipolar disorder families
This study watches how a person’s mood and movement change over time, and how those patterns relate to bipolar disorder. It may help researchers better understand the condition in families and potentially improve future care.
Bethesda, MarylandAges 8–70 - NCT07408934Enrolling by invitation
Group therapy for feeling safer with psychosis
This trial tests a group therapy program called the Feeling Safe Programme for people with psychosis. It aims to help you learn new ways to cope with your symptoms and feel safer. It meets once a week for 75 minutes.
Ottawa, OntarioAges 18 years+ - NCT07732660Recruiting
Building skills and reducing stigma for young people with HIV in Zambia
This trial helps young people aged 18 to 24 living with HIV in three districts of Zambia. It aims to reduce stigma and build job skills to improve their lives.
Lusaka, Lusaka ProvinceAges 18–24 - NCT01434368Recruiting
How the brain and hormones change during puberty
This study follows healthy 8‑year‑olds over time to understand how hormones and brain development change during puberty. Participants will have MRI scans, X‑rays, and other tests to track normal growth.
Bethesda, MarylandAges 7–35 - NCT04106713Recruiting
Understanding change across different psychotherapies for anxiety and depression
This study looks at how people change during different types of psychotherapy for anxiety and depression. It aims to understand which treatments work best for different people.
Singapore, SingaporeAges 18–99 - NCT06233344RecruitingPhase 2
Mindfulness and psilocybin study for healthy adults
This study tests whether combining mindfulness training with a single dose of psilocybin (a psychedelic found in certain mushrooms) can help healthy adults. It aims to explore how these two approaches together might improve well-being.
Los Angeles, CaliforniaAges 25 years+ - NCT06969742Recruiting
Mental health program for young cancer survivors and caregivers
This trial tests a program to help improve mental health and quality of life for teenagers and young adults who have had a solid tumor cancer, and for their caregivers. It focuses on those recently finished treatment or still in treatment, and aims to provide supportive counseling.
Goyang-si, Gyonggi-doAges 10–24 - NCT06926361Recruiting
Mindfulness for teacher well-being and teaching
This study tests whether an 8-week mindfulness course can help teachers feel better and improve their teaching. If you're a teacher who can make time for weekly classes, this may be a way to reduce stress and boost well-being.
Hong KongAges 21–65 - NCT06963554Recruiting
Does Project Support help families after trauma?
This study tests a program called Project Support to help families deal with trauma. If you're a caregiver looking for trauma services for your 6-to-13-year-old child, and you can do telehealth sessions, this may be a good fit.
Charleston, South CarolinaAges 6–13 - NCT06777823Recruiting
Social media and mental health study for girls aged 10-11
This study looks at how social media affects the mental health of girls going through puberty. It tests whether sensitivity to rejection and puberty stage make some girls more vulnerable to social media experiences.
St Louis, MissouriAges 10 years+ - NCT06659315Recruiting
Preventing HIV transmission from mom to baby for depressed mothers in Malawi
This study tests a program to help pregnant women with HIV who also have depression, and their partners, reduce the risk of passing HIV to their babies. The program includes support for mental health and HIV care.
ZombaAges 18 years+ - NCT06581874Recruiting
Mental health care follow-up after emergency visit
This study is testing a new way of coordinating mental health care between the hospital and community providers. It aims to see if this collaborative approach helps people who need follow-up after an emergency visit or a referral through the Med@psy program.
Toulon, VarAges 18 years+ - NCT06490094Recruiting
Mental health support for new mothers
This trial tests a method called IBSR (Inquiry-Based Stress Reduction) to see if it can help new mothers feel better mentally. It is for mothers who have given birth within the last two years and have no history of mental health conditions.
Tel AvivAges 18–45 - NCT06208358Recruiting
Testing brain stimulation for gaming disorder
This study tests if a gentle brain stimulation technique (tACS) can help people with severe gaming disorder by improving how they interact with others. It aims to understand and treat the social challenges linked to the condition.
Shanghai, Shanghai MunicipalityAges 18–60
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Common questions
- Are there clinical trials for mental health?
- Yes. Clin2 currently lists 725 recruiting mental health studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mental health trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mental health trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.