Clinical trials
Moderate Dementia clinical trials
Below are recruiting moderate dementia clinical trials, each written for real people, not researchers. We’re tracking 12 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06245031Enrolling by invitation
Long-term follow-up of sensory stimulation for Alzheimer's
This is a follow-up study for people who already completed the 12-month Hope Study (CA-0011). It tests long-term safety and effects of a gentle sensory stimulation device (light and sound) for Alzheimer's disease. You will continue using the device at home with a study partner.
Phoenix, ArizonaAges 50–92 - NCT07033468Recruiting
Virtual reality cognitive training for mild to moderate dementia
This study tests whether using a full-immersive virtual reality program can help improve thinking and memory skills in people with mild or moderate dementia. It aims to see if this type of training is both possible and helpful.
New Taipei CityAges 55 years+ - NCT06854718Recruiting
Pain Management Study for People with Dementia
This study tests a new approach to help people with dementia who have chronic pain. It looks at how caregivers can support pain management at home.
Durham, North CarolinaAges 50 years+ - NCT07208162Recruiting
SHARE program for African American families facing memory loss
This study tests a program called SHARE, which helps African American families work together when a loved one has early-stage memory loss. It focuses on improving communication and support at home.
Cleveland, OhioAges 18 years+ - NCT07625241Recruiting
Brain and Movement Training for Mild-to-Moderate Dementia
This study tests two types of training—cognitive (brain) and movement exercises—for people with mild-to-moderate dementia. The goal is to see if these activities together can help improve thinking, memory, and physical function.
Genova, GenovaAges 65 years+ - NCT07081750Recruiting
Home activity program for dementia patients after hospital stay
This study tests a personalized home activity program for people with mild-to-moderate dementia who are leaving the hospital. It helps both the patient and their main family caregiver by giving them simple activities to do together at home.
Fujian, FuzhouAges 60 years+ - NCT07066826RecruitingPhase 2/Phase 3
Huperzine A for mild-to-moderate Alzheimer's dementia
This study tests whether Huperzine A controlled-release tablets can help improve memory and thinking in people with mild-to-moderate Alzheimer's disease. You'll take the tablets or a placebo to see if it slows down dementia symptoms.
BeijingAges 50–85 - NCT04500847RecruitingPhase 1
Testing repurposed HIV-like drugs for early Alzheimer’s symptoms
This Phase 1 study tests whether an existing type of anti-viral medicine (nucleoside reverse transcriptase inhibitors) can help people with early Alzheimer’s disease. It also focuses on safety and proper dosing while measuring brain-related changes and memory-related symptoms.
Los Angeles, CaliforniaAges 50–85 - NCT06584357Recruiting
Digital and blood markers linked to brain scans in older adults
This study is looking for older adults (60–90) who are either cognitively normal, have mild cognitive impairment (MCI), or have mild-to-moderate Alzheimer's dementia. It aims to see how digital tests and blood-based markers relate to brain scans (amyloid and tau PET). You will need a study partner, undergo MRI and PET scans, and give blood samples.
Atlantis, FloridaAges 60–90 - NCT06534723RecruitingPhase 3
Wujia Yizhi granules for mild-to-moderate Alzheimer's
This trial tests if a Chinese herbal granule (Wujia Yizhi) can help people with mild-to-moderate Alzheimer's dementia. It is for patients who have memory problems for at least 6 months and meet specific Alzheimer's biomarker criteria.
Fuzhou, FujianAges 50–80 - NCT06338215Recruiting
Moderate drinking vs. abstention advice for adults
This study compares two approaches for adults who drink regularly: advice on drinking in moderation vs. advice to stop drinking entirely. The goal is to see which approach better prevents major diseases and early death over time.
Pamplona, NavarreAges 50–75 - NCT06597942RecruitingPhase 1/Phase 2
Deep TMS for Alzheimer's disease
This trial tests a non-invasive brain stimulation technique called deep repetitive TMS on a brain region linked to memory. It aims to see if this treatment can improve symptoms in people with mild-to-moderate Alzheimer's disease.
Los Angeles, CaliforniaAges 60–100
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Common questions
- Are there clinical trials for moderate dementia?
- Yes. Clin2 currently lists 12 recruiting moderate dementia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a moderate dementia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a moderate dementia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.