Clinical trials
Alzheimer Dementia (AD) clinical trials
Below are recruiting alzheimer dementia (ad) clinical trials, each written for real people, not researchers. We’re tracking 139 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07786116Recruiting
Gut bacteria in Parkinson's disease and related conditions
This study looks at how certain gut bacteria (methanogens) are involved in the progression of Parkinson's disease and related conditions. It aims to understand the connection between gut health and brain health, which may lead to better treatments.
Cambridge, CB2Ages 55 years+ - NCT04906863Recruiting
Genetic study for early dementia in adults and families
This trial studies genes to better understand why some people develop dementia and memory problems earlier in life. It may help researchers find clearer causes and improve future testing and treatments for families affected by dementia.
New York, New YorkAges 35 years+ - NCT05911932Recruiting
Genetic testing in people with memory or nerve diseases
This study looks at genetic (inherited) information using a blood sample from people who come to a memory/cognitive clinic, including some with related family history. Results may help researchers understand who is at risk and how these conditions develop.
London, OntarioAges 18 years+ - NCT05950607Recruiting
Nursing home study to reduce unnecessary antibiotic use
This study looks at ways to lower how often antibiotics are used in nursing home residents with Alzheimer’s disease and other dementias. It aims to make antibiotic use more appropriate while monitoring resident outcomes.
Boston, MassachusettsAges 60–106 - NCT07693140RecruitingPhase 1/Phase 2
Low-dose radiation therapy for Alzheimer's disease
This trial tests if very low doses of radiation to the brain can reduce inflammation and slow memory loss in people with Alzheimer's or similar dementias. It involves monthly clinic visits for a year.
Winter Park, FloridaAges 50 years+ - NCT06508268Recruiting
Language, speech, and movement in early Alzheimer's
This study looks at how language, speech, and motor skills change in people with mild cognitive impairment (early memory problems) due to Alzheimer's disease, and in people with Alzheimer's disease. It also includes healthy older adults for comparison. The goal is to better understand these changes, which may help with earlier diagnosis.
GroningenAges Any age - NCT06597942RecruitingPhase 1/Phase 2
Deep TMS for Alzheimer's disease
This trial tests a non-invasive brain stimulation technique called deep repetitive TMS on a brain region linked to memory. It aims to see if this treatment can improve symptoms in people with mild-to-moderate Alzheimer's disease.
Los Angeles, CaliforniaAges 60–100 - NCT06922188Recruiting
Screening for financial hardship in Alzheimer's and dementia
This study aims to develop a way to measure financial hardship in people with Alzheimer's disease, related dementias, and their caregivers. By taking part, you can help create a tool that may identify financial struggles and connect families with needed support.
Seattle, WashingtonAges 18 years+ - NCT06965062Recruiting
Neck surgery for Alzheimer's: a first test
This study tests a new surgery called cervical lymphatic bypass to see if it can help people with Alzheimer's disease. The surgery creates a new connection in the neck to improve drainage of waste from the brain, which may slow memory loss.
SingaporeAges 50–80 - NCT07143734RecruitingPhase 2
Brain stimulation for early Alzheimer's disease
This study tests a new, noninvasive brain stimulation method called Transcranial Pulse Stimulation (TPS) for people in the early stages of Alzheimer's disease. The goal is to see if it can help improve symptoms.
Hong KongAges 60–90 - NCT07218081RecruitingPhase 1
Intermittent deep brain stimulation for early Alzheimer's
This trial tests a treatment that sends gentle electrical pulses to a part of the brain involved in memory and thinking. It is for people with early-stage Alzheimer's who live at home and have a caregiver who can help.
Augusta, GeorgiaAges 65–85 - NCT07222280Recruiting
Alzheimer's dementia and brain inflammation trial
This trial tests if treating brain inflammation can help older adults hospitalized with sudden confusion or cognitive issues. It may help those without a prior dementia diagnosis but who have toxic or metabolic causes for their symptoms.
Crossville, TennesseeAges 60–90 - NCT07234695RecruitingPhase 3
Levetiracetam to prevent seizures in adults with Down syndrome and Alzheimer's
This trial tests if levetiracetam, a seizure medication, can prevent seizures in adults with Down syndrome who also have Alzheimer's disease. It aims to help manage a common complication and improve quality of life.
Granada, AndalusiaAges 40 years+ - NCT07279740RecruitingPhase 2
Brain stimulation plus medication for apathy in dementia
This study tests if combining a type of brain stimulation (repetitive TMS) with a medication (methylphenidate, commonly used for ADHD) can improve apathy in people with dementia. If you have Alzheimer's or mixed dementia and struggle with low motivation, this trial may help you.
Toronto, OntarioAges Any age - NCT07676851Recruiting
Predicting dementia risk in older adults with depression
This study looks at whether certain health factors can predict the risk of dementia in older adults who have depression. Your medical records will be reviewed to help create a risk score.
Nanchang, JiangxiAges 50 years+ - NCT07422857RecruitingPhase 3
A PET scan for detecting signs of Alzheimer's
This trial uses a new type of PET scan to look for specific proteins in the brain that are linked to Alzheimer's disease. It will help doctors see how these proteins relate to cognitive decline and compare scans from people with normal thinking to those with memory problems.
Wuhan, HubeiAges 50 years+ - NCT07516119Recruiting
Predicting Alzheimer's Risk Before Memory Loss Occurs
This study identifies people at high risk for Alzheimer's disease before symptoms develop, using genetics and digital tools to track brain health over time. If you qualify, you'll help researchers understand who will develop cognitive decline and potentially enable earlier interventions.
San Diego, CaliforniaAges 55 years+ - NCT07604896RecruitingPhase 4
Lecanemab for early Alzheimer's disease with amyloid buildup
This trial tests lecanemab, an infusion medicine that targets amyloid protein buildup in the brain, in people with mild cognitive impairment or mild Alzheimer's disease. Researchers will track how well it works and study how it affects your body's proteins using advanced lab tests.
Wenzhou, ZhejiangAges 50–90 - NCT07618481Recruiting
Brain Stimulation Study for Alzheimer's Disease
This study tests whether a special type of brain stimulation called 40Hz BCI (brain-computer interface) might help slow memory loss in people with Alzheimer's disease. You would receive daily stimulation sessions at home with help from a caregiver.
Shanghai, Shanghai MunicipalityAges 50–80 - NCT07651319RecruitingPhase 1/Phase 2
IL-2 and Semaglutide Treatment for Alzheimer's Disease
This study tests whether two drugs—IL-2 (an immune-boosting medication) and semaglutide (a diabetes drug that may help brain function)—can slow memory loss in people with Alzheimer's disease. Researchers believe these drugs together might help reduce brain inflammation and protect memory.
Houston, TexasAges 50–86 - NCT06245031Enrolling by invitation
Long-term follow-up of sensory stimulation for Alzheimer's
This is a follow-up study for people who already completed the 12-month Hope Study (CA-0011). It tests long-term safety and effects of a gentle sensory stimulation device (light and sound) for Alzheimer's disease. You will continue using the device at home with a study partner.
Phoenix, ArizonaAges 50–92 - NCT04786223Enrolling by invitationPhase 2
Testing an anti-inflammatory PET imaging treatment in memory loss
This Phase 2 study tests whether targeting “neuroinflammation” (inflammation in the brain) can help in Alzheimer’s disease and related memory disorders. You may help researchers by doing several brain scans (including a special PET/CT scan) along with MRI and amyloid imaging to understand what’s happening in the brain.
Rochester, MinnesotaAges 60 years+ - NCT03402919Recruiting
Brain and memory study for people with thinking changes
This study looks at memory and thinking changes using questionnaires, memory testing, and brain scans. It may help researchers better understand neurodegeneration and dementia and how these problems show up over time.
Calgary, AlbertaAges 50–90 - NCT05245903Recruiting
Test a supplement and track brain changes with wearable sensors
This study tests whether taking nicotinamide riboside (a form of niacin) affects early memory changes in people with mild cognitive impairment (MCI) or mild Alzheimer’s disease (AD). It also uses passive wearable or sensor data (“digital biomarkers”) to measure changes over time.
Belmont, MassachusettsAges 18–89
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Alzheimer Dementia (AD) trials by city
Studies with a site in or near these metro areas.
Alzheimer Dementia (AD) trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for alzheimer dementia (ad)?
- Yes. Clin2 currently lists 139 recruiting alzheimer dementia (ad) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a alzheimer dementia (ad) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a alzheimer dementia (ad) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.