Clinical trials
Musculoskeletal Diseases or Conditions clinical trials
Below are recruiting musculoskeletal diseases or conditions clinical trials, each written for real people, not researchers. We’re tracking 4,063 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04612322Recruiting
Study registry for microvascular angina patients
This registry study collects information from adults with microvascular angina (chest pain from small blood vessels in the heart). It may help researchers better understand how to assess and manage this condition over time.
Mainz, RLPAges 18–85 - NCT04626167RecruitingEarly Phase 1
Testing a bladder transplant done with a kidney transplant
This early-phase study is testing a combined bladder and kidney transplant approach for people whose bladder problems damage the kidneys. The goal is to see if this treatment can improve bladder and kidney outcomes and be done safely.
Rochester, MinnesotaAges 1–60 - NCT04631471RecruitingPhase 3
Ibudilast for spinal cord pressure from neck wear
This Phase 3 study tests ibudilast, a medicine, to see if it can improve symptoms in people whose neck arthritis has started compressing the spinal cord. You would still have your usual surgery to relieve the pressure, and then take the study medicine to see if recovery and function improve.
CambridgeAges 18–80 - NCT04635436Recruiting
Split-walking training for one-sided leg weakness when walking hurts
This trial tests whether a “split gait” walking training method can improve walking balance and how you move when you have one-sided leg problems and pain or limitations when walking. It may help reduce walking difficulties by training your stepping pattern safely.
Milan, MIAges 18–70 - NCT04662294RecruitingEarly Phase 1
CD70-targeted CAR T therapy for CD70-positive blood cancers
This trial tests a customized immune-cell treatment (CAR T) that targets CD70 on cancer cells in certain blood cancers. It may help people whose disease has returned or did not respond to standard treatments.
Hangzhou, ZhejiangAges Any age - NCT04663750RecruitingPhase 3
Surgery to treat bleeding under the retina in wet macular degeneration
This trial tests whether a specific eye surgery plus targeted clot-busting medicine and gas can improve vision after bleeding under the retina from “wet” age-related macular degeneration. It aims to reduce how long the bleeding lasts and help protect the central vision.
BonnAges 50–120 - NCT04664491Recruiting
Program to reduce COPD flare-ups with standardized care
This study tests whether a structured care program for COPD can lower how often your symptoms flare up. It may help by improving everyday management and preventing future worsening.
Beijing, Beijing MunicipalityAges 40 years+ - NCT04676828Recruiting
SPECT-guided radiation to avoid healthy lung in lung cancer
This study tests a special imaging-guided radiation plan that aims to treat lung cancer while reducing radiation to healthy lung tissue. It may help lower lung side effects while keeping the cancer treatment focused on tumor areas.
Sydney, New South WalesAges 18 years+ - NCT04678401RecruitingPhase 1
Trial tests transplant using a half-matched donor for high-risk leukemia
This Phase 1 trial tests a special bone marrow transplant using a related “half-matched” donor (haploidentical), without a specific immune-suppressing medicine (“IS-free”). It’s for adults with certain high-risk AML or MDS to see if this approach can improve control of the disease while tracking safety.
Boston, MassachusettsAges 18–75 - NCT04679844Recruiting
Test bone putty for back fusion versus bone graft alternatives
This study compares a ready-to-use bone putty to standard bone graft materials (with or without your own bone) during back fusion surgery for unstable lower back problems. It looks at whether the putty works as well or better to help the bones fuse and heal.
Irvine, CaliforniaAges 18 years+ - NCT04681534Recruiting
Testing safer adaptive deep brain stimulation for Parkinson’s
This trial studies an “adaptive” form of deep brain stimulation (DBS) that adjusts based on brain signals, and is mainly done when the DBS battery (IPG) needs replacement or when people are getting DBS for the first time. It aims to improve safety and effectiveness for Parkinson’s symptoms by using recorded brain activity during treatment.
MilanAges Any age - NCT04692675Recruiting
MRI study to track prostate cancer in active surveillance patients
This study uses special prostate MRI scans to see how prostate cancer changes over time while you stay on active surveillance. It also looks at prostate tissue to understand your cancer’s genetics, which may help guide future decisions.
Bethesda, MarylandAges 18 years+ - NCT04722835Recruiting
Study lung immune cells in people at risk for COPD
This study looks at different lung immune cell patterns and how they work in smokers who are not yet diagnosed with COPD or asthma. It may help researchers understand why some people are more likely to develop COPD, which could guide future prevention or early treatments.
San Francisco, CaliforniaAges 40–75 - NCT04725617Recruiting
Smoking-quit program for people with HIV and sleep issues
This study tests a wellness-based smoking-cessation program (including the stop-smoking medicine varenicline) for people living with HIV who want to quit. It aims to help you reduce or stop smoking while monitoring safety, sleep, and mental health during the program.
Phoenix, ArizonaAges 18–75 - NCT04728841Recruiting
Gene therapy trial for Chinese hemophilia A
This trial tests a one-time gene therapy treatment (GS001) to help people with hemophilia A make more of the clotting factor they lack. If it works and is safe for you, it could improve how well blood clots form over time.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT04735835Recruiting
Personalized diet testing using ZOE app and blood samples
This trial studies how different food compositions affect your body, using the ZOE testing program plus meals you eat and blood samples you collect. It may help you learn more about what foods work best for you, especially if you have a long-term health condition.
Needham, MassachusettsAges 18 years+ - NCT04742634RecruitingPhase 1/Phase 2
Preemptive drug DEC-C after transplant to reduce hidden cancer
This trial tests whether giving DEC-C (a decitabine-based treatment) soon after an allogeneic transplant can improve outcomes for MDS patients who still have “measurable residual disease” (hidden leftover disease) detectable by a genetic test. It also compares this approach to standard observation if the hidden disease is not detected or if the higher-risk safety checks are not met.
St Louis, MissouriAges 18–75 - NCT04741230Recruiting
Test implant for severe corneal thinning to avoid transplant
This study tests a procedure called Xenia corneal lenticule in people with severe keratoconus or severe post-LASIK corneal thinning who want to avoid a corneal transplant. It aims to improve vision while checking safety and how well the new procedure works over time.
Wolverhampton, West MidlandsAges 18–79 - NCT04748237Recruiting
CT heart scan for intermediate-risk chest pain
This study tests whether a special heart CT scan can help evaluate the cause of chest pain in people at intermediate risk for blocked heart arteries. It may help doctors decide what to do next after an emergency room visit.
StockholmAges 18 years+ - NCT04759274Recruiting
Personalized water pill dosing support for kidney and fluid overload
This trial tests a decision-support tool to help your care team safely adjust water pills (“diuretics”) when you have kidney disease and fluid buildup. It may help reduce swelling by guiding dosing using your home weight and blood pressure.
Dallas, TexasAges 18 years+ - NCT04761120Recruiting
Follow-up study for specific heart valve repair ring implants
This study follows people who are going to get certain types of heart valve repair rings or bands. It aims to track safety and outcomes after the Abbott device is implanted in routine care over follow-up visits.
Durham, North CarolinaAges 18 years+ - NCT04767074Recruiting
Non-drug therapy to reduce long-term cough in lung scarring
This study tests a non-medication cough-control program for people who have lung scarring (interstitial lung disease) and a cough lasting more than 8 weeks. It may help you control coughing better without adding new medicines.
Hamilton, OntarioAges 18–85 - NCT04772170Recruiting
Study wearable and symptom monitoring during respiratory virus challenges
This observational study looks for digital health patterns during studies where people are intentionally exposed to a respiratory virus. If you join a respiratory virus challenge at NIH, you may help researchers discover better ways to monitor and understand illness using wearable devices and shared health data.
Bethesda, MarylandAges 18–65 - NCT04775914Recruiting
Test a heart procedure guide during emergency STEMI treatment
This trial studies whether adding a special heart “reset” step (ischemic postconditioning) and using an imaging guide during the emergency procedure can improve outcomes for people having a STEMI heart attack. It’s meant to optimize treatment when a blocked heart artery is being opened.
Copenhagen, Capital RegionAges 18 years+
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Common questions
- Are there clinical trials for musculoskeletal diseases or conditions?
- Yes. Clin2 currently lists 4,063 recruiting musculoskeletal diseases or conditions studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a musculoskeletal diseases or conditions trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a musculoskeletal diseases or conditions trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.