Clinical trials
Negative Pressure Wound Therapy clinical trials
Below are recruiting negative pressure wound therapy clinical trials, each written for real people, not researchers. We’re tracking 31 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06717308Recruiting
Testing a gentler adhesive drape for wound therapy
This trial compares a special adhesive drape (the switchable one) with the standard drape during negative pressure wound therapy (a treatment that uses suction to help heal wounds after surgery). The goal is to see if the new drape causes less pain when removed.
Los Angeles, CaliforniaAges 18 years+ - NCT06725459Recruiting
Negative pressure wound therapy after breast reduction surgery
This study tests if a special wound dressing (negative pressure wound therapy) helps healing after breast reduction surgery. It may reduce scarring and improve recovery for women having this specific type of breast reduction.
Washington D.C., District of ColumbiaAges 18 years+ - NCT05169814RecruitingEarly Phase 1
Microbubble treatment for certain burn and wound types
This early-stage study tests micro/nanobubbles placed on or used for certain types of difficult wounds, including burns and some pressure or diabetic foot ulcers, especially when there has been tissue injury from radiation. It may help wounds heal faster or more effectively, but it is still being studied in early phases.
Orange, CaliforniaAges 18 years+ - NCT05615844RecruitingPhase 3
Antibiotic beads versus negative pressure dressing for severe leg fractures
This Phase 3 study compares two ways to help heal a severe open tibia (shin bone) fracture and prevent complications like infection. If you qualify, you may receive antibiotic beads or a negative pressure wound therapy dressing after urgent wound cleaning.
Chandler, ArizonaAges 18 years+ - NCT07607366Recruiting
Negative Pressure Bandaging After Breast Removal Surgery
This trial tests a special bandage that uses gentle suction to help wounds heal better after breast cancer surgery. Researchers want to see if this type of bandaging reduces complications like fluid buildup and improves healing.
FalunAges 18 years+ - NCT07120386Recruiting
Comparing two wound vacuum methods for severe skin infections
This study compares two wound care methods after emergency surgery for a serious skin infection. One method uses a standard wound vacuum, and the other uses a wound vacuum that also irrigates (rinses) the wound to see if it helps with healing.
Saint Paul, MinnesotaAges 18 years+ - NCT07065734RecruitingPhase 4
Vacuum bandage after kidney transplant
This trial tests whether a special vacuum bandage (negative pressure wound therapy) helps heal the surgical wound after a kidney transplant. It may reduce complications and improve recovery.
PortoAges 18 years+ - NCT06181097Recruiting
Negative pressure wound therapy after knee or hip replacement
This study tests whether using a special bandage that applies gentle suction (negative pressure wound therapy) after knee or hip replacement helps incisions heal better. It may reduce wound complications and improve recovery.
Hong KongAges 50 years+ - NCT06647290Recruiting
Wound care after pilonidal sinus surgery
This trial compares different wound care methods for people having surgery for pilonidal sinus (a small tunnel in the skin near the tailbone). It aims to find the best way to help the wound heal after the sinus is removed.
Dublin, DublinAges 18 years+ - NCT06025253Recruiting
Negative pressure dressing after leg amputation
This trial tests a special wound dressing that applies gentle suction to the incision after major leg amputation. It aims to reduce wound complications and help the stump heal better.
Dublin, DublinAges 18 years+ - NCT07489820Recruiting
Vacuum dressing for healing after rectal cancer surgery
This trial is testing whether a special vacuum-type wound dressing (called negative pressure therapy) helps the surgical area heal better after removal of the rectum and anus for rectal cancer. If you've had chemotherapy and radiation before surgery, this study may help improve your recovery.
AmiensAges 18 years+ - NCT03175718Recruiting
Pre-surgery radiation to reduce complications after leg sarcoma surgery
This study looks at whether giving radiation before surgery can lower wound healing problems and improve outcomes after operating on a leg soft-tissue sarcoma. It focuses on patients whose surgeons can close the wound directly after surgery and who can return for follow-up visits.
Ottawa, OntarioAges 18 years+ - NCT04003038Recruiting
Negative pressure wound dressings after breast reconstruction in obesity
This trial tests whether a special “suction” dressing (negative pressure wound therapy) helps wounds heal better after breast reconstruction using tissue from the belly, especially in people with higher body weight. You may be more likely to benefit if you’re at higher risk for wound problems after abdominal flap surgery.
Houston, TexasAges 18 years+ - NCT05598398RecruitingPhase 4
Wound dressing method for severe pressure sores
This trial studies a special negative-pressure wound dressing used during closure surgery for stage 3–4 pressure sores. The goal is to help wounds heal by improving how well the wound is sealed.
Chicago, IllinoisAges 18 years+ - NCT06259409RecruitingPhase 1
Reggenn therapy system safety study for back pain
This trial tests a new treatment system for people with a slipped vertebra (spondylolisthesis) or worn-out discs (degenerative disc disease) causing back or leg pain. The goal is to see if the treatment is safe.
Kansas City, KansasAges 18–80 - NCT06265558Recruiting
Vacuum dressing to prevent wound problems after breast cancer surgery
This study tests a special vacuum dressing (negative pressure therapy) to prevent wound problems after complex breast cancer surgery. It's for women who have risk factors for poor healing and are having a mastectomy with immediate reconstruction or a certain breast-conserving surgery.
Dijon, Côte d'OrAges 18 years+ - NCT06337292RecruitingPhase 3
Wound vacuum therapy for high-risk leg fractures
This trial tests if a special wound vacuum (negative pressure therapy) applied after surgery can lower the risk of infections and other complications in people with severe leg fractures. If you have a high-risk tibia or ankle fracture, this treatment may help you heal better.
Baltimore, MarylandAges 18 years+ - NCT07342049Recruiting
Negative pressure therapy with silver for chronic leg wounds
This trial tests a special wound vacuum system with silver to treat chronic leg ulcers that show signs of infection. It aims to see if this dressing helps clean and heal wounds better.
Santiago, Santiago MetropolitanAges 18 years+ - NCT06721754Recruiting
Negative pressure therapy for diabetic foot ulcers
This study tests if a vacuum-like wound dressing (negative pressure wound therapy) helps heal diabetic foot ulcers after surgery. It may be a good fit if you have a foot ulcer needing surgery and are able to walk.
Oslo, NordbyhagenAges 18 years+ - NCT06832787Recruiting
Negative pressure therapy for diabetic foot wounds
This study tests whether combining negative pressure wound therapy (a special dressing that uses gentle suction) can help diabetic foot wounds heal better after toe amputation. It is looking for people who have had their big or little toe removed and have adequate blood flow to the foot.
SingaporeAges 21–100 - NCT06941194Recruiting
Preventing wound problems after sarcoma surgery with a special bandage
This trial tests a special negative pressure bandage used after surgery to prevent wound complications in people with high-grade soft tissue sarcoma of the limbs who have had radiation therapy before their operation.
Padova, Italy/PadovaAges 18–99 - NCT06957964Recruiting
Does a special wound dressing help prevent infection after belly surgery?
This trial tests a special wound dressing (negative pressure therapy) used right after belly surgery to see if it helps prevent wound problems. It may be an option for people who are having a first-time laparotomy and are in good general health.
Lahore, Punjab ProvinceAges 20–70 - NCT07003906Recruiting
Negative pressure therapy for emergency belly surgery incisions
This trial tests if negative pressure wound therapy (a special dressing that uses gentle suction) helps heal large cuts from emergency belly surgery better than a standard dressing. It may reduce infections and improve recovery.
EskilstunaAges 18 years+ - NCT07040683Recruiting
Vacuum dressing for skin grafts on lower leg
This study compares standard wound care to a special vacuum dressing (negative pressure therapy) after skin graft surgery on the lower leg for skin cancer. The goal is to see if the vacuum dressing helps the graft heal better.
MalmöAges 18 years+
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Common questions
- Are there clinical trials for negative pressure wound therapy?
- Yes. Clin2 currently lists 31 recruiting negative pressure wound therapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a negative pressure wound therapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a negative pressure wound therapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.