Clinical trials · South Carolina
Opioid Use Disorder clinical trials in South Carolina
We’re tracking 15 recruiting opioid use disorder studies with a site in South Carolina — including Early Phase 1, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in South Carolina
- NCT07278518Recruiting
Emergency department decision aid for buprenorphine
This trial is testing a tool to help people in the emergency department decide whether to start buprenorphine (a medication for opioid use disorder). It's for patients who are not already on medication for their condition.
Charleston, South CarolinaAges 18 years+ - NCT07631598Recruiting
Buprenorphine at Needle Exchange Programs to Prevent Overdoses
This study tests whether offering buprenorphine (a medication that reduces cravings and withdrawal) directly at syringe service programs (places where people get clean needles) can help people with opioid addiction stay safe and reduce overdose risk. If you use opioids and visit a syringe service program, this may be an option to explore.
Greenville, South CarolinaAges 18 years+ - NCT07044466Recruiting
Social functioning study for people in treatment for opioid use
This study looks at how people recovering from opioid use disorder get along with a close friend or family member (called a CSO). It may help improve social support during early treatment.
Charleston, South CarolinaAges 18 years+ - NCT06655883RecruitingPhase 3
Testing suvorexant for insomnia in people with opioid use disorder
This study tests whether the sleep medication suvorexant (Belsomra) can help people with opioid use disorder who also have trouble sleeping. If you are stable on medication for opioid use disorder and have not used opioids in the last month, this trial may be an option for you.
Charleston, South CarolinaAges 18–70 - NCT06651177RecruitingPhase 2
Tirzepatide with buprenorphine for opioid use disorder
This study tests whether adding tirzepatide, a medication used for weight and blood sugar, to buprenorphine treatment helps people with opioid use disorder. It aims to see if the combination improves outcomes compared to buprenorphine alone.
Greenville, South CarolinaAges 18 years+ - NCT06608979Recruiting
Trauma screening and violence prevention for women in addiction treatment
This study offers trauma screening and a program to help prevent interpersonal violence for women who are currently receiving treatment for substance use. It aims to understand how these services can improve safety and well-being.
Greenville, South CarolinaAges 18 years+ - NCT06641115Recruiting
Integrated treatment for opioid use disorder and PTSD
This study tests a combined therapy for people with both opioid use disorder and PTSD. It aims to help you manage both conditions together, rather than treating them separately.
Charleston, South CarolinaAges 18–70 - NCT06999811Recruiting
Technology vs. medication monitoring for buprenorphine in pregnancy
This study compares two approaches to help pregnant people stay on buprenorphine (a medication for opioid use disorder): one uses technology to support therapy, and the other uses standard medication monitoring. It aims to see which method works better for keeping you in treatment during pregnancy.
Charleston, South CarolinaAges 18–45 - NCT06157840Recruiting
Sleep program for people on buprenorphine treatment
This trial tests a mobile health sleep program for people who are on buprenorphine for opioid use disorder and have trouble sleeping. It aims to help improve sleep and support your recovery journey.
Charleston, South CarolinaAges 18 years+ - NCT06479681Recruiting
Coaching help for alcohol use recovery in hospital
This trial tests if a peer recovery coach can help people with alcohol use disorder stay sober after being hospitalized. You'll get support from someone who has been through recovery themselves.
Greenville, South CarolinaAges 18–75 - NCT07421102RecruitingEarly Phase 1
Mailing buprenorphine after hospital stay
This study tests whether mailing buprenorphine (a medication for opioid use disorder) to patients after they leave the hospital helps them stay on treatment. If you started buprenorphine in the hospital and are heading home to South Carolina, this option might make it easier to continue your recovery.
Charleston, South CarolinaAges 18 years+ - NCT07202039Recruiting
E-Cigarettes for Smokers on Buprenorphine
This study tests whether switching to electronic cigarettes can help reduce harm for people with opioid use disorder who are on buprenorphine and smoke daily. The goal is to see if e-cigarettes are a safer option than continuing to smoke regular cigarettes.
Greenville, South CarolinaAges 21 years+ - NCT07541417Recruiting
Peer Support for Starting Medication Treatment for Opioid Use
This study tests whether peer coaches—people with lived experience of opioid addiction—can help newly enrolled patients stay engaged with medication-based treatment through a mobile app. The goal is to improve treatment success by combining peer support with digital health tools.
Greenville, South CarolinaAges 18 years+ - NCT06039566RecruitingPhase 3
NAC vs placebo for pain after hysterectomy
This trial tests if a medicine called N-acetylcysteine (NAC) can reduce the need for strong pain pills after hysterectomy surgery. If you are having a laparoscopic or robotic hysterectomy, this study may help you recover with less opioid pain medicine.
Charleston, South CarolinaAges 18 years+ - NCT06420336Recruiting
Pain relief after cleft palate surgery
This study compares two ways to manage pain after cleft palate repair surgery that uses a bone graft from the hip. The goal is to see which method provides better pain control for children and teens.
Charleston, South CarolinaAges 6–18
Opioid Use Disorder trials by city in South Carolina
Where these studies are running in South Carolina
Institutions with a site for the recruiting opioid use disorder studies listed above.
- Medical University of South Carolina · 9 studies
- Prisma Health Cancer Institute · 5 studies
- Addiction Medicine Center
- Oconee Memorial Hospital
- The Phoenix Center
What taking part in a opioid use disorder study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Opioid Use Disorder trials in other states
Common questions
- Are there opioid use disorder clinical trials in South Carolina?
- Yes. We're currently tracking 15 recruiting opioid use disorder studies with a site in South Carolina, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a opioid use disorder study in South Carolina?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in South Carolina to take part?
- Not necessarily. These studies have a site in South Carolina, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a opioid use disorder trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New opioid use disorder studies open in South Carolina regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.