Clinical trials · New York
Opioid Use Disorder clinical trials in New York
We’re tracking 23 recruiting opioid use disorder studies with a site in New York — including Early Phase 1, Phase 1, Phase 1/Phase 2, Phase 2, Phase 2/Phase 3, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in New York
- NCT03135886Recruiting
Testing for HIV in opioid treatment programs
This project studies how to improve offering and completing HIV (and hepatitis C) tests in opioid treatment programs. It may help increase timely follow-up and linkage to care when results are positive.
New York, New YorkAges 18 years+ - NCT06548490RecruitingPhase 2
Semaglutide for Opioid Use Disorder
This study tests whether a once-weekly injection of semaglutide (a GLP-1 receptor agonist) can reduce opioid use in people who are already on buprenorphine or methadone but still using opioids. It lasts about 19 weeks.
New York, New YorkAges 18–75 - NCT07665502Enrolling by invitation
Smartphone app to boost opioid treatment for women facing violence
This study tests a smartphone app (WINGS+++) to help women who have experienced intimate partner violence and trauma improve their engagement with medication for opioid use disorder (MOUD). The goal is to see if the app makes it easier to start and stay on treatment.
New York, New YorkAges 18 years+ - NCT07420283RecruitingPhase 2
Study of Brenipatide for opioid use disorder
This trial tests a new medicine called Brenipatide for people with opioid use disorder who are already taking buprenorphine but still occasionally use non-prescribed opioids. It aims to see if the study drug can help reduce opioid use.
New York, New YorkAges 18–75 - NCT04197921Recruiting
Brain-focused ultrasound for opioid addiction-related substance use
This trial studies Exablate, a non-surgical brain treatment that aims to change activity in a specific brain area involved in cravings and substance use. It is meant for people in structured opioid or substance use treatment who are currently abstaining from opioids and other illicit drugs.
New York, New YorkAges 18–60 - NCT04458545RecruitingPhase 1/Phase 2
Opioid vaccine study for adults with heroin or fentanyl use
This trial tests a vaccine made from parts designed to help the body respond to opioids (heroin or fentanyl). It is mainly for adults with moderate-to-severe opioid use disorder who are using opioids that match the study dosing needs and who are willing to do frequent visits over about a year.
New York, New YorkAges 18–59 - NCT05011266RecruitingPhase 2/Phase 3
Buprenorphine plus naltrexone shot to prevent opioid relapse
This trial tests whether a combination of buprenorphine (through your care plan) and a monthly extended-release naltrexone (XR-NTX) shot can help prevent opioid relapse. It may help people who are ready to move toward a naltrexone-based relapse-prevention treatment after detox.
New York, New YorkAges 18–65 - NCT05450718RecruitingPhase 4
Low-dose buprenorphine start for opioid use disorder
This trial tests whether starting buprenorphine using a low-dose plan is a safe and workable way to treat opioid use disorder. You may be able to join if you are 18+, have opioid use disorder, and can follow the study medication and visits.
The Bronx, New YorkAges 18 years+ - NCT05614661Recruiting
Postpartum support for mothers using opioid treatment
This study tests a postpartum intervention for mothers diagnosed with opioid use disorder (or receiving opioid addiction treatment) to help during the period after having a baby. You may be eligible if you have a young child and can complete the study tasks, including possible questionnaires and an MRI if needed.
Stony Brook, New YorkAges 18–50 - NCT05722561RecruitingPhase 2
E-cigarettes to reduce smoking in opioid use disorder
This Phase 2 study tests whether e-cigarettes can help people who use opioids (and also smoke cigarettes) cut down on combustible cigarette smoking. It looks at whether switching to e-cigarettes for “harm reduction” is safe and helps you smoke fewer cigarettes without requiring you to quit completely.
The Bronx, New YorkAges 21–75 - NCT06458335Recruiting
Treating opioid use and loneliness
This study tests a program to help people with opioid use disorder who also feel lonely. It aims to see if treating both together can improve your health and wellbeing.
Rochester, New YorkAges 18 years+ - NCT06569667Recruiting
AI and peer coaching for Black and Latinx adults using opioids
This study tests whether AI and peer coaching can help Black and Latinx people who use opioids start buprenorphine treatment and reduce racial disparities. It's designed for people in New York City who are interested in starting this medication.
The Bronx, New YorkAges 18–99 - NCT06573476Recruiting
Smartphone app and peer coach for opioid treatment
This study tests whether a smartphone app and support from a peer recovery coach can help Black and Latinx individuals with opioid use disorder start buprenorphine treatment. The goal is to reduce overdose deaths and address racial gaps in care.
New York, New YorkAges 18–99 - NCT06726200RecruitingEarly Phase 1
Comparing buprenorphine formulations for fentanyl addiction
This study tests two different forms of buprenorphine (a medication for opioid addiction) to see which works better for people who use fentanyl or other strong synthetic opioids. If you are seeking treatment for opioid use, this trial may help you find the most effective option.
New York, New YorkAges 18–65 - NCT06796062RecruitingPhase 2
Psilocybin for opioid use disorder
This study tests whether psilocybin can help people who want to stop using opioids and are already in treatment. Eligible participants receive a single dose of psilocybin in a supervised setting and are followed to see if it reduces opioid use.
The Bronx, New YorkAges 18–65 - NCT06940674RecruitingPhase 3
CBD plus opioid treatment for recovery
This study tests whether adding cannabidiol (CBD) to your usual methadone or buprenorphine treatment helps you recover from opioid use disorder. If you're already in stable treatment with those medications, the trial aims to see if CBD can improve your outcomes.
New York, New YorkAges 18–65 - NCT07632053Recruiting
Support Program for Mothers With Opioid Addiction
This study offers support and treatment for mothers struggling with opioid use disorder who have a child age 5 or younger. Researchers will provide intervention and assess brain imaging to understand how best to help mothers and their families.
Stony Brook, New YorkAges 18–50 - NCT03667846RecruitingPhase 2
Biomarker-guided treatment for drinking and PTSD symptoms
This Phase 2 study tests whether blood/brain “biomarkers” can help choose a treatment plan for people who have alcohol use disorder and PTSD. The goal is to improve outcomes related to drinking and PTSD symptoms compared with a standard approach.
New York, New YorkAges 18–70 - NCT05675735Recruiting
Methadone take-home program to help people stay in treatment
This trial studies whether changing how methadone is allowed to be taken home can improve how long people stay in opioid use disorder treatment. It focuses on clinics and on adults who have already been receiving take-home methadone.
Buffalo, New YorkAges 18 years+ - NCT05033028RecruitingPhase 3
Using a smartphone to support opioid addiction recovery
This Phase 3 study tests whether using smartphones can help people with opioid-use disorder stick with treatment and recover more successfully. It focuses on people starting or already in treatment using methadone or buprenorphine, with support delivered through the study app or messages.
New York, New YorkAges 18–85 - NCT06051890RecruitingPhase 4
Assessing switching to long-acting buprenorphine injection in jail
This study tests whether switching from daily buprenorphine/naloxone (Suboxone) to a long-acting injectable buprenorphine (XRB) is safe and effective for men who are unsentenced and in jail for at least 4 days. It aims to see if the injection can help continue treatment without needing daily medication.
New York, New YorkAges Any age - NCT04084860RecruitingPhase 2
Brief medicine trial to help reduce heavy alcohol drinking
This Phase 2 study tests a brief medication approach meant to reduce “problem drinking.” It may help people cut back or stop alcohol use by adjusting brain signaling related to drinking cravings and urges.
New York, New YorkAges 21–70 - NCT07447856RecruitingPhase 1
Herbal plasters for pain relief while using opioids
This trial tests a topical herbal plaster to see if it can help reduce pain in people with cancer who are already taking opioids. The plaster is placed on the most painful area and may allow you to use less opioid medication.
Harrison, New YorkAges 18 years+
Opioid Use Disorder trials by city in New York
Where these studies are running in New York
Institutions with a site for the recruiting opioid use disorder studies listed above.
- NYU Langone Health · 7 studies
- New York State Psychiatric Institute · 3 studies
- START Treatment and Recovery / START New York · 2 studies
- Stony Brook University · 2 studies
- Weill Cornell Medicine · 2 studies
- Adams Clinical Bronx
- Adams Clinical Harlem
- Albert Einstein College of Medicine
What taking part in a opioid use disorder study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Opioid Use Disorder trials in other states
Common questions
- Are there opioid use disorder clinical trials in New York?
- Yes. We're currently tracking 23 recruiting opioid use disorder studies with a site in New York, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a opioid use disorder study in New York?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in New York to take part?
- Not necessarily. These studies have a site in New York, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a opioid use disorder trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New opioid use disorder studies open in New York regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.