Clinical trials
Osteoarthritis (OA) clinical trials
Below are recruiting osteoarthritis (oa) clinical trials, each written for real people, not researchers. We’re tracking 82 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07464080Recruiting
Brain imaging study for knee replacement patients
This study uses advanced brain scans to understand how pain and recovery change after knee replacement surgery. It may help researchers develop better ways to manage pain after surgery.
Ottawa, OntarioAges 18 years+ - NCT07351981Enrolling by invitation
Cooled radiofrequency for knee osteoarthritis pain
This study tests a new approach called cooled radiofrequency (TcPRF) to calm knee pain from osteoarthritis. It may be an option if standard treatments haven't worked and you haven't had certain other treatments recently.
AthensAges 45 years+ - NCT06932614Recruiting
Growth factor vs PRP for knee arthritis
This trial compares two injections—a special growth factor treatment and a platelet-rich plasma (PRP) injection—to see which works better for knee osteoarthritis. It aims to help people with mild to moderate knee arthritis who have had pain for at least 3 months.
TaipeiAges 20–80 - NCT06872567Recruiting
Knee artery block vs. steroid injection for arthritis pain
This study compares two treatments for knee arthritis pain: a procedure that blocks blood flow to the painful area (genicular artery embolization) versus a steroid injection into the knee joint. The goal is to see which one provides better pain relief.
Charlottesville, VirginiaAges 40 years+ - NCT05839535RecruitingPhase 2
Baduanjin plus brain stimulation for knee osteoarthritis pain
This Phase 2 study tests whether combining Baduanjin (a guided mind-body movement) with neuromodulation can improve knee osteoarthritis symptoms and function. It compares education-based stretching/control and uses MRI scanning as part of the research.
Charlestown, MassachusettsAges 45–75 - NCT06485843RecruitingPhase 2
Testing a new injection for moderate to severe knee osteoarthritis
This study tests the safety of an experimental injection called OA-SYS for people with moderate to severe knee osteoarthritis. It may help if you have not had recent injections or certain other health problems.
Las Vegas, NevadaAges 35–75 - NCT07804199Recruiting
Ear nerve stimulation for knee osteoarthritis pain in veterans
This study tests whether a small device that stimulates a nerve in your ear can help reduce knee pain caused by osteoarthritis. If you join, you'll be asked to stop taking your current knee pain medicines during the trial, but you can use a safe rescue medicine (acetaminophen/paracetamol) if needed.
Decatur, GeorgiaAges 45–75 - NCT05495334Recruiting
Add knee osteoarthritis outcomes to a patient registry
This study tests a new way to collect how people with knee osteoarthritis feel and function after usual care (like injections, nerve-blocking procedures, or knee replacement). It may help improve future treatment decisions by using your regular follow-up reports in an app or online.
Phoenix, ArizonaAges Any age - NCT07754175Recruiting
Stem cell knee treatment for osteoarthritis patients
This study tests a stem cell injection for knee osteoarthritis in patients who previously received a placebo. It aims to see if the treatment is safe and effective over a longer period.
SeoulAges 19 years+ - NCT06084364RecruitingPhase 4
Steroid vs saline injection vs occupational therapy for thumb arthritis
This study compares a steroid injection (Kenacort), a saltwater (saline) injection, and occupational therapy to see which works best for thumb base osteoarthritis pain. It may help you if you have thumb pain with swelling and want to avoid surgery.
BodøAges 40–85
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Common questions
- Are there clinical trials for osteoarthritis (oa)?
- Yes. Clin2 currently lists 82 recruiting osteoarthritis (oa) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a osteoarthritis (oa) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a osteoarthritis (oa) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.