Testing a new injection for moderate to severe knee osteoarthritis
Part of Bones, joints & muscles clinical trials.
This study tests the safety of an experimental injection called OA-SYS for people with moderate to severe knee osteoarthritis. It may help if you have not had recent injections or certain other health problems.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age between 35 and 75 years
- Body mass index (BMI) less than 39
- Knee osteoarthritis that is moderate to severe (X-ray grade 3 or 4)
- No inflammatory arthritis (like rheumatoid arthritis) or autoimmune disease
- No steroid or biologic injections (like PRP or stem cells) in any joint in the past 6 months
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies knee tissue to find better ways to diagnose early osteoarthritis. It may help people who need a knee injection for pain relief.
This study tests if an injection made from amniotic fluid can reduce knee pain and improve function in people with moderate knee osteoarthritis. The goal is to give a long-lasting alternative to steroid or gel shots.
This study tests a new knee injection called CX-011 to see if it can reduce pain and improve function in people with knee osteoarthritis. It may be a good option if you have tried other treatments without enough relief.
This trial tests a new type of knee injection called CCoat for people with mild to moderate knee osteoarthritis. The goal is to see if it helps reduce pain, stiffness, and joint symptoms.
This study tests a new cell-based injection (Allocetra) directly into the knee joint for people with moderate osteoarthritis who haven't benefited from other treatments. The goal is to reduce pain and improve knee function.
This study tests a new investigational medicine injected into the knee to see if it is safe and tolerable for people with painful knee osteoarthritis. It may help reduce pain and improve knee function.
Hear when a new Osteoarthritis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.