Clinical trials
Pancreaticoduodenectomy clinical trials
Below are recruiting pancreaticoduodenectomy clinical trials, each written for real people, not researchers. We’re tracking 26 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05992857Recruiting
Omentum wrap to prevent leaks after Whipple surgery
This trial tests if wrapping a flap of abdominal tissue (omentum) around the arteries during Whipple surgery (pancreaticoduodenectomy) can reduce the risk of a serious leak. It may help patients who have a higher fistula risk score (7 or more) during their open surgery.
ClichyAges 18 years+ - NCT05788029Enrolling by invitation
Laparoscopic vs open pancreatic surgery for periampullary cancer
This trial compares two ways of doing a major pancreas-and-duodenum operation: laparoscopic (small incisions) versus open surgery (larger incision). It aims to see which approach works better for nonpancreatic periampullary adenocarcinoma when the goal is cure.
Wuhan, HubeiAges 18–75 - NCT07744087Recruiting
Comparing two surgical methods for removing tumors near the pancreas
This trial compares two types of surgery to remove tumors that start near the pancreas but not in it. The goal is to see if a newer, less invasive method works as well as the standard approach, which may mean fewer cuts and a faster recovery.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT03747588Recruiting
Laparoscopic versus open surgery for pancreas cancer
This study compares two ways of doing pancreaticoduodenectomy (a major surgery to remove parts of the pancreas and nearby tissue): minimally invasive (often smaller incisions) versus open surgery. It may help clarify which approach works best when the cancer looks potentially removable.
Beijing, Beijing MunicipalityAges 18–75 - NCT07328607Recruiting
Comparing Keyhole vs Open Pancreas Surgery
This trial compares two surgical approaches for removing tumors in the head of the pancreas or nearby areas: 'keyhole' (laparoscopic) surgery versus traditional open surgery. The goal is to see if the keyhole method offers similar results with a faster recovery.
Minya, Minya GovernorateAges 18–75 - NCT07370987RecruitingPhase 2
Preventing pancreatic fistula after surgery with pre-surgery radiation
This trial tests if a short course of radiation before surgery can lower the risk of a pancreatic leak (a common complication). It is for people who are overweight, older than 45, and have a small pancreatic duct.
ParisAges 45 years+ - NCT06322680Recruiting
Drain tubes to prevent pancreas leak after Whipple surgery
This trial is testing whether draining the main pancreatic and bile ducts during a Whipple procedure can lower the risk of a pancreatic leak. The study focuses on people with a higher chance of this complication.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06801899Recruiting
Total vs. partial Whipple for high-risk pancreatic cancer
This trial compares removing the entire pancreas (total pancreatectomy) versus removing only the head (standard Whipple) for certain cancers of the pancreas, bile duct, or ampulla. It is for people whose surgeon thinks the pancreas connection after surgery is likely to leak, which can cause serious complications.
MünsterAges 18 years+ - NCT07009119Recruiting
Laparoscopic surgery for pancreatic and bile duct cancers
This trial tests a minimally invasive surgery called laparoscopic pancreaticoduodenectomy to remove certain cancers in the pancreas, bile duct, or nearby areas. It may help patients whose cancer has not spread and can be fully removed with surgery.
MinyaAges 18–75 - NCT07681128Recruiting
Studying a new surgical stitch to help stomach emptying after pancreas surgery
This trial is testing whether adding a special connection (Braun anastomosis) between two parts of the small intestine during pancreas surgery can reduce delayed stomach emptying, a common problem after the procedure.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT07022015Recruiting
Predicting pancreatic leak after pancreatic surgery
This trial looks at factors that can predict a serious complication called a pancreatic fistula (a leak from the pancreas) after a Whipple procedure. The goal is to help doctors better understand and manage this risk.
MinyaAges 18–75 - NCT06685939Enrolling by invitation
Comparing recovery after two types of pancreatic cancer surgery
This study compares two surgeries for pancreatic cancer: laparoscopic (keyhole) pancreaticoduodenectomy and open pancreaticoduodenectomy. It aims to see which approach leads to fewer complications during recovery.
ShanghaiAges 19 years+ - NCT07502053Recruiting
Can a dye help prevent a pancreas leak after Whipple surgery?
This trial tests if using a special dye during surgery can reduce the risk of a pancreatic fistula (a leak from the pancreas) after a Whipple procedure. The dye helps the surgeon see blood flow to the remaining pancreas, which may improve healing.
Girona, GironaAges 18 years+ - NCT07321470Recruiting
Nasogastric tube care after pancreas surgery
This trial compares two ways of managing nasogastric tubes after pancreas and bile duct surgery. One group gets a tube for a while, the other avoids one. It tests if skipping the tube helps recovery.
Taipei, Zhongzheng DistrictAges 20–75 - NCT05843877RecruitingPhase 3
Surgery choice and insulin islet transplant to prevent leaks
This Phase 3 trial studies a pancreatic surgery approach (pylorus-preserving Whipple or similar) and, in some cases, moving your insulin-making cells into your body to help prevent a dangerous post-surgery leak from the pancreas. It may help people who are considered high risk for this complication based on pancreas texture and duct size.
DresdenAges 18 years+ - NCT03785743Recruiting
Compare keyhole vs open surgery for pancreatic cancer
This trial compares two ways of doing surgery for pancreatic cancer: keyhole (small cuts) versus open surgery (one larger cut). It’s meant to see which approach works better for people who are well enough for either option.
Wuhan, HubeiAges 18–75 - NCT07703813Recruiting
Energy use and nutrition after pancreas surgery
This study measures how your body uses energy after pancreas surgery to improve nutrition care. It may help doctors better support your recovery.
Athens, AtticaAges 18–75 - NCT04571294Recruiting
Removing lymph nodes during Whipple surgery for pancreatic cancer
This study looks at removing certain lymph nodes near the aorta while doing a standard Whipple operation for pancreatic head cancer. The goal is to see whether this approach can improve how well doctors manage the cancer spread.
Rozzano, Italy/MilanAges 18 years+ - NCT05725590Recruiting
External pancreatic duct stents after pancreatic surgery
This study tests whether placing an external pancreatic duct stent after pancreaticoduodenectomy can lower the risk of pancreatic leak (pancreatic fistula). If you had this surgery with a specific connection technique, you may be able to help find a safer way to prevent complications.
HangzhouAges 18–75 - NCT06761989Recruiting
Comparing two ways to control pain after Whipple surgery
This study compares two ways to manage pain after a Whipple procedure: one is a shot of morphine into the fluid around the spine, and the other is a small tube placed under the skin at the surgical cut that delivers pain medicine continuously. The goal is to see which method provides better pain relief and recovery.
Seoul, SeoulAges 19 years+ - NCT06852014Recruiting
Nutritional supplement study for malnourished pancreatic cancer patients
This trial tests whether a special drink called Peptamen 1.6 can help improve nutrition and recovery in patients who are malnourished or at risk and have had surgery for pancreatic cancer. It aims to understand how the supplement affects the body right after surgery.
Málaga, MálagaAges 18 years+ - NCT07132541RecruitingPhase 1
New surgical glue technique for pancreas connection after Whipple surgery
This trial tests a new method using a surgical glue called N-butyl-2-cyanoacrylate to seal the pancreas after a Whipple procedure. It may help prevent leaks and improve recovery for patients with a soft pancreas and small pancreatic duct.
Minya, Minya GovernorateAges 18–75 - NCT07144917Recruiting
Immune system changes after Whipple surgery
This study is looking at how the immune system can become weakened after a Whipple procedure for pancreatic tumors. The goal is to better understand and potentially help patients recover more effectively.
LyonAges 18 years+ - NCT07148830Recruiting
Surgery technique study for pancreatic cancer patients
This trial tests a specific surgical method called mesopancreatic excision during Whipple surgery for pancreatic cancer. It may help remove more cancer tissue and improve outcomes for patients with resectable disease.
Minya, Minya GovernorateAges 18–75
Hear when a new Pancreaticoduodenectomy trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for pancreaticoduodenectomy?
- Yes. Clin2 currently lists 26 recruiting pancreaticoduodenectomy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pancreaticoduodenectomy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pancreaticoduodenectomy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.