Clinical trials
Personality Disorder clinical trials
Below are recruiting personality disorder clinical trials, each written for real people, not researchers. We’re tracking 138 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04870255Recruiting
Brain stimulation for depression in borderline personality disorder
This study tests a type of brain stimulation called rTMS to see if it can help improve mood in people who have both depression and borderline personality disorder. It may offer a new treatment option for those who haven't tried TMS before.
Stanford, CaliforniaAges 18–80 - NCT06789380Recruiting
Generalist vs specialist care for severe personality disorders
This trial compares two types of treatment—generalist care by a therapist or specialist care—for people with severe personality disorders. It aims to find which approach works better and is more cost-effective.
Halsteren, North BrabantAges 18 years+ - NCT06913738Recruiting
Extended therapy for borderline personality disorder
This study tests a longer version of a therapy called Good Psychiatric Management for people with borderline personality disorder (BPD). It aims to see if the extended program helps symptoms more than usual care.
BayonneAges 18 years+ - NCT07197502Recruiting
Treating borderline personality disorder with brain stimulation
This study tests if a non-invasive brain stimulation technique called rTMS can help treat borderline personality disorder (BPD). It aims to see if this treatment can improve symptoms and is safe for people with BPD.
Los Angeles, CaliforniaAges 18–65 - NCT07337889Recruiting
Borderline personality as a relationship disorder study
This study compares people with borderline personality disorder, bipolar disorder, and healthy controls to understand how relationships are affected. It may help find better ways to support people with these conditions.
MontpellierAges 18–45 - NCT07341438Recruiting
Physical activity for personality disorders
This trial is testing whether physical activity can help people with borderline or avoidant personality disorder. It is open to adults who are already getting treatment at two specific clinics in Denmark.
Gentofte Municipality, Capital RegionAges 18 years+ - NCT07460947RecruitingPhase 1/Phase 2
One-day TMS and medicine for suicidal thoughts in BPD
This trial tests if a single day of accelerated transcranial magnetic stimulation (TMS) combined with the medication D-cycloserine can reduce suicidal thoughts in people with borderline personality disorder (BPD). It aims to find a fast-acting treatment option for those who are struggling.
Belmont, MassachusettsAges 18 years+ - NCT03994510Recruiting
Study of shame in borderline personality disorder
This study looks at how people with borderline personality disorder experience shame and how that relates to symptoms and behavior. The goal is to better understand shame so future treatments can be more targeted.
Montpellier, HéraultAges 18 years+ - NCT04211753Recruiting
Mobile app support for emotional crises in borderline personality disorder
This study tests whether a smartphone app (B·RIGHT) can help people manage emotional crises related to borderline personality disorder, and checks that it is safe. If you match the diagnosis and age range, the app may be offered as part of the research.
Mataró, BarcelonaAges 18–60 - NCT05246527Recruiting
Exercise study to see effects in borderline personality disorder
This study looks at how a physical exercise session affects thinking and other outcomes in people diagnosed with borderline personality disorder. It may help researchers understand whether exercise has short-term benefits or risks for this group.
Bonn, North Rhine-WestphaliaAges 18–50 - NCT05913544Recruiting
Integrative therapy for young adults with borderline personality disorder
This trial tests a short integrative therapy program along with repeated thinking (neurocognitive) and mental health assessments for young adults with borderline personality disorder (BPD). It may help improve symptoms and cognitive functioning by combining structured therapy and targeted evaluations.
NîmesAges 16–25 - NCT06106555Recruiting
What helps in DBT for borderline personality disorder
This study looks at what helps people get better from Dialectical Behaviour Therapy (DBT) for borderline personality disorder. It will track factors like self-harm and therapy progress to understand what works best.
Lund, Skåne CountyAges 18 years+ - NCT06446765RecruitingPhase 2
Mindfulness and brain feedback to boost BPD therapy
This study tests whether combining mindfulness training with brain scan feedback (neurofeedback) can improve the benefits of regular talk therapy for adults with borderline personality disorder. It takes place at Yale University.
New Haven, ConnecticutAges 18–60 - NCT06458933RecruitingPhase 2
Couples therapy for borderline personality disorder
This study tests talk therapy for couples where one person has borderline personality disorder (BPD). It aims to see if the therapy helps improve symptoms and relationship quality.
Toronto, CaliforniaAges 19 years+ - NCT06493708Recruiting
EMDR Therapy for Borderline Personality Disorder
This study tests whether Eye Movement Desensitization and Reprocessing (EMDR) therapy can help people with Borderline Personality Disorder (BPD). EMDR is a type of talk therapy often used for trauma, and this trial wants to see if it can improve BPD symptoms.
Brescia, BresciaAges 18–65 - NCT06563466Recruiting
Pegasus: Better treatment for emotional instability
This study tests a new way to treat emotionally unstable personality disorder (also called borderline personality disorder) by including family or close friends in therapy. It aims to see if this approach improves how patients feel and function.
CopenhagenAges 18 years+ - NCT06683014RecruitingPhase 2
MDMA study for borderline personality disorder
This trial tests if a single dose of MDMA, given under supervision, can help people with borderline personality disorder (BPD). You will stay overnight after the session and be followed up for two weeks.
New Haven, ConnecticutAges 18–60 - NCT06880640Recruiting
Impulsivity in borderline personality disorder
This study looks at how emotions affect impulsive behaviors in people with borderline personality disorder (BPD). It aims to understand these patterns better, which could help improve future treatments.
Chapel Hill, North CarolinaAges 18–45 - NCT07342907Recruiting
Internal Family Systems therapy for borderline personality disorder
This study tests a type of talk therapy called Internal Family Systems (IFS) to see if it helps people with borderline personality disorder (BPD). You would attend 50 therapy sessions over about 12-15 months to explore how this approach may improve your symptoms and well-being.
Tiny, OntarioAges 18 years+ - NCT02097706RecruitingPhase 2
Drug study for borderline personality disorder
This Phase 2 study tests a new medicine for people with borderline personality disorder (BPD) to see if it can improve symptoms. You may qualify if you have a confirmed BPD diagnosis and meet safety and medication rules.
Melbourne, VictoriaAges 18–65 - NCT07639957Recruiting
How Gender Affects Borderline Personality Disorder
This study explores how borderline personality disorder (BPD)—a condition affecting emotions, relationships, and self-image—may differ based on gender identity. Researchers want to understand these differences to improve diagnosis and treatment for all patients.
HeidelbergAges 18–65 - NCT06863909Enrolling by invitation
Journaling plus cognitive behavioral therapy for better results
This trial explores whether adding journaling to your regular cognitive behavioral therapy sessions helps you feel better more quickly. You keep seeing your therapist as usual, just add a few minutes of writing each day.
TübingenAges 18–65 - NCT05986552Enrolling by invitation
How group or individual therapy affects schema therapy for BPD
This study compares individual and group formats of schema therapy for borderline personality disorder (BPD). It aims to see which format works better for reducing symptoms and improving daily life.
AmsterdamAges 18–70 - NCT07398365Recruiting
Medical study of psychiatry inpatients
This study looks at the medical and mental health patterns of adults admitted to general adult psychiatry wards. It aims to better understand their health needs.
Livingston, West LothianAges 18–65
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Common questions
- Are there clinical trials for personality disorder?
- Yes. Clin2 currently lists 138 recruiting personality disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a personality disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a personality disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.