Clinical trials
Positive Mental Health clinical trials
Below are recruiting positive mental health clinical trials, each written for real people, not researchers. We’re tracking 87 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07027839RecruitingPhase 1
Alcohol effects on brain imaging for phosphodiesterase
This study uses PET scans to see how alcohol affects a protein in the brain called PDE4B. It may help explain how alcohol works in the body.
Bethesda, MarylandAges 21–70 - NCT07031544Recruiting
Deep brain stimulation for severe OCD
This study tests whether implanting a small device deep in the brain—like a pacemaker for OCD—can help people whose severe OCD hasn't gotten better with standard medications and therapy.
Guangzhou, GuangdongAges 18–65 - NCT00001360Recruiting
Brain Blood Flow During Thinking Study
This research study uses brain imaging to see how blood flows in your brain while you think and perform tasks. Researchers hope to better understand how healthy brains work during different types of thinking.
Bethesda, MarylandAges 18–65 - NCT01266577Recruiting
MRI study measuring brain and muscle chemical levels
This study uses MRI techniques to measure natural chemical “metabolites” in the brain and muscle. You may be able to join if you’re generally healthy and can safely complete a long MRI scan.
Bethesda, MarylandAges 18–65 - NCT00109174Recruiting
Brain scan study measuring glutamate and GABA
This study uses MRI to measure certain chemicals in the brain (glutamate and GABA) and see how they are metabolized. You may be able to join if you are healthy, can safely have an MRI, and meet the specific enrollment requirements.
Bethesda, MarylandAges 18–65 - NCT02543983RecruitingPhase 2
Brain scan and ketamine study for suicidal thoughts
This trial studies how ketamine affects the brain in people dealing with suicidal thoughts or an active suicide crisis. It uses questionnaires, consent testing, and brain imaging to look for biological changes that may relate to symptom improvement.
Bethesda, MarylandAges 18–70 - NCT03065335RecruitingPhase 1
Ketamine plus brain imaging to study response in depression
This early-stage study tests how ketamine given once and then repeatedly may change brain signals and related biomarkers in people with major depression. If you’re eligible, the team will use brain imaging and assessments to see who responds and why.
Bethesda, MarylandAges 18–65 - NCT07428460Recruiting
Speedy brain stimulation for persistent negative symptoms in schizophrenia
This trial tests if a new, faster form of brain stimulation called accelerated neuromodulation therapy can help reduce negative symptoms (like loss of motivation or social withdrawal) in people with schizophrenia. It aims to see if this treatment can improve daily functioning and quality of life.
Montreal, QuebecAges 18–65 - NCT07579143Recruiting
VA mental health and chaplain teamwork for moral injury
This study tests whether having a VA mental health clinician and chaplain work together helps veterans with moral injury—feeling distressed after witnessing or being part of something they feel was wrong. You'll receive PTSD or substance use treatment with this added support.
Little Rock, ArkansasAges 18–80 - NCT06226818Recruiting
Support for women experiencing sexual or domestic violence
This trial compares two types of care—women's centers versus traditional health centers—to see which better supports the mental and physical health of women who have faced sexual or domestic violence. It aims to find the best way to help women heal.
DijonAges 18 years+ - NCT06878859Recruiting
Online program for depression and cannabis use
This study tests a digital (online) program designed to help people who struggle with both depression and cannabis use. If you're feeling down and also using cannabis more than you'd like, this program might help you manage both.
Boston, MassachusettsAges 18 years+ - NCT06900712Recruiting
Single-session program for sexual assault recovery
This trial tests a one-time session designed to help survivors of unwanted sexual contact or assault reduce symptoms of PTSD or depression. It may be a good fit if you live in Ohio and have had these symptoms for at least a month.
Cleveland, OhioAges 18–65 - NCT07687524Recruiting
Study on parent-child interaction for healthy growth
This study looks at how parents and children interact day to day to help support healthy growth. It tests a program that teaches parents about everyday behavior patterns to strengthen their relationship with their child.
Singapore, SingaporeAges 2–65 - NCT07020533RecruitingPhase 1
CMV vaccine for stem cell transplant recipients
This trial tests a vaccine designed to boost immunity against CMV (a common virus) and prevent active CMV infection in people receiving a half-matched stem cell transplant. It may help protect you from CMV-related complications after transplant.
Duarte, CaliforniaAges 18–75 - NCT05013944Recruiting
Join a patient registry to support future research
This trial is a “patient registry,” which collects health information over time to help researchers plan and run future studies. It may help by contributing your experience so new treatments can be tested more effectively.
Arlington Heights, IllinoisAges 18 years+
Hear when a new Positive Mental Health trial opens
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Common questions
- Are there clinical trials for positive mental health?
- Yes. Clin2 currently lists 87 recruiting positive mental health studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a positive mental health trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a positive mental health trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.