Clinical trials
Postpartum Depression (PPD) clinical trials
Below are recruiting postpartum depression (ppd) clinical trials, each written for real people, not researchers. We’re tracking 22 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07766161Recruiting
Light therapy for postpartum depression
This trial tests whether timed light therapy can improve postpartum depression symptoms. It focuses on new mothers within six months of giving birth who have elevated depression scores.
Ann Arbor, MichiganAges 18 years+ - NCT07607613Recruiting
Support for LGBTQ+ Parents with Depression Risk
This study offers group support sessions for LGBTQ+ parents who are pregnant or recently had a baby and are experiencing mild depression or worry about postpartum depression. The goal is to help prevent depression from getting worse and improve emotional well-being during this important life transition.
Chicago, IllinoisAges 18 years+ - NCT06818734Recruiting
Testing a tool for postpartum depression screening
This trial tests a tool that helps doctors screen for postpartum depression during pregnancy. You may be eligible if you are at least 20 weeks pregnant and receive care at a participating clinic.
Brooklyn, New YorkAges 18 years+ - NCT07721961RecruitingPhase 3
Study of MI078 for postpartum depression
This trial tests a new medication, MI078, to see if it can help women with postpartum depression. You may qualify if you are between 18 and 45, have given birth within the last year, and are currently experiencing moderate to severe depression that started in late pregnancy or shortly after delivery.
Hefei, AnhuiAges 18–45 - NCT06682689Recruiting
Nerve stimulation study for new mothers' mental health
This study tests whether a gentle nerve stimulation device (tVNS) worn on the ear can help new mothers feel better emotionally after childbirth. It is for women whose babies had normal organ scans and who do not have certain medical conditions or current mood disorders.
Tübingen, Baden-WurttembergAges 18 years+ - NCT06698107Recruiting
Childbirth education for teen mothers to prevent depression
This program tests a special childbirth education class designed to help first-time teen mothers feel more confident and prepared, with the goal of reducing the chance of depression after the baby is born.
Bahir Dar, AmharaAges 13–19 - NCT06996067Recruiting
Parent coaching texts after first baby in Nova Scotia
This trial tests a text message program to support new parents after childbirth. It aims to help you feel more confident and connected during the early weeks at home.
Halifax, Nova ScotiaAges 18 years+ - NCT06777563Recruiting
Mood app and check-ins to prevent postpartum depression
This study tests whether using a smartphone program (mHealth) along with emotional support (EMA) can help prevent postpartum depression in pregnant women who are feeling distressed. It is for women in Hong Kong who are at 20–28 weeks of pregnancy and have mild to moderate mood symptoms.
Hong Kong, PokfulamAges 18 years+ - NCT06831968Recruiting
Blood test to predict postpartum depression risk
This study tests a new blood test to predict who might get postpartum depression (sadness or mood changes after giving birth). If you are early in your pregnancy (less than 30 weeks), you may be able to join and help find out if the test works.
Charlottesville, VirginiaAges 18 years+ - NCT06833788RecruitingPhase 4
IV vs. oral iron for anemia after c-section and depression risk
This trial compares intravenous (IV) iron with oral iron pills to treat anemia after a C-section, and looks at whether iron treatment affects the risk of postpartum depression. You may be eligible if you had a C-section, are at least 18, delivered at 32 weeks or later, have mild to moderate anemia, and low iron stores.
ParisAges 18 years+ - NCT07186309Recruiting
At-home test for postpartum depression study
This trial is testing a way to screen for postpartum depression from the comfort of your home. You would take a test during pregnancy to see if it can help find women who may be at risk.
Charlottesville, VirginiaAges 18 years+ - NCT07210255Recruiting
SAINT TMS for postpartum depression
This trial tests a special type of TMS (brain stimulation) called SAINT for severe depression that started around childbirth. It may help new mothers who are still within a year postpartum and have not found relief from other treatments.
Worcester, MassachusettsAges 18–45 - NCT07272252Recruiting
Nursing support to reduce anxiety after planned C-section
This study tests a special kind of nursing care (narrative nursing) to see if it helps mothers feel less anxious and more confident about breastfeeding after a planned, full-term cesarean section. If you are having a scheduled C-section with a healthy pregnancy and baby, you may be able to join.
Nanchong, SichuanAges 18–50 - NCT07292649Recruiting
Labor pain relief and postpartum depression risk
This study looks at how your expectations about pain relief during labor might affect your mood after giving birth. Researchers will follow you after delivery to see if there is a link between your hopes for pain management and the risk of postpartum depression.
Padova, VenetoAges 18 years+ - NCT07382336Recruiting
Smartphone app to detect postpartum depression early
This study tests a mobile app that tracks mood changes during pregnancy to help detect postpartum depression early. If you are pregnant in your first or second trimester, can read Chinese, and have a smartphone, you may be able to join.
Hong KongAges 18 years+ - NCT07384273Recruiting
Online therapy for postpartum depression symptoms
This trial tests an internet-based therapy program (iCARE) to help new mothers manage symptoms of postpartum depression. It may be a good fit if you gave birth within the last 6 months and have been feeling down or depressed.
OdenseAges 18 years+ - NCT06770244Enrolling by invitation
Positive psychology for postpartum depression in primary care
This trial tests a program based on positive psychology to help prevent or reduce postpartum depression. It is offered within the primary healthcare system and focuses on supporting mothers early in pregnancy.
Wuhan, HubeiAges 18 years+ - NCT07214597Recruiting
Using voice technology to improve NICU mom experience
This trial tests a smartphone app called VoiceLove that lets moms record their voice for their baby in the NICU. It may help mothers feel more connected and supported while their baby is in the hospital.
Nashville, TennesseeAges 18 years+ - NCT05700760Recruiting
ROSE program study to prevent postpartum depression
This study tests whether a program called ROSE can help prevent postpartum depression after delivery. If you’re pregnant, you may be asked to complete questionnaires and be reached by phone for study steps.
Flint, MichiganAges 18 years+ - NCT07398469Recruiting
Long-term study of zuranolone for postpartum depression symptoms
This study checks how people with postpartum depression feel over time after starting zuranolone. It uses simple questionnaires to track changes in symptoms.
Cambridge, MassachusettsAges 18 years+ - NCT07047820Recruiting
Studying zuranolone for postpartum depression after pregnancy
This study looks at how the medicine zuranolone (taken for postpartum depression) works in real life for people who got a prescription within a year after their pregnancy ended. Researchers want to see if symptoms improve and how participants feel while taking it.
Woonsocket, Rhode IslandAges 18 years+ - NCT07440355Enrolling by invitation
Light therapy for postpartum depression and baby development
This study looks at how light therapy for mothers with postpartum depression might affect their baby's development. It involves babies born to mothers who are already part of a larger postpartum depression treatment study.
Porto Alegre, Rio Grande do SulAges Any age
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Common questions
- Are there clinical trials for postpartum depression (ppd)?
- Yes. Clin2 currently lists 22 recruiting postpartum depression (ppd) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a postpartum depression (ppd) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a postpartum depression (ppd) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.