Clinical trials
Postpartum Depression clinical trials
Below are recruiting postpartum depression clinical trials, each written for real people, not researchers. We’re tracking 73 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07766161Recruiting
Light therapy for postpartum depression
This trial tests whether timed light therapy can improve postpartum depression symptoms. It focuses on new mothers within six months of giving birth who have elevated depression scores.
Ann Arbor, MichiganAges 18 years+ - NCT07594743Recruiting
Digital app to prevent depression in new fathers
This study tests a smartphone app designed to help fathers manage stress and mood after their baby is born. Researchers want to see if fathers find the app helpful and easy to use during this major life change.
Providence, Rhode IslandAges 18 years+ - NCT06818734Recruiting
Testing a tool for postpartum depression screening
This trial tests a tool that helps doctors screen for postpartum depression during pregnancy. You may be eligible if you are at least 20 weeks pregnant and receive care at a participating clinic.
Brooklyn, New YorkAges 18 years+ - NCT07721961RecruitingPhase 3
Study of MI078 for postpartum depression
This trial tests a new medication, MI078, to see if it can help women with postpartum depression. You may qualify if you are between 18 and 45, have given birth within the last year, and are currently experiencing moderate to severe depression that started in late pregnancy or shortly after delivery.
Hefei, AnhuiAges 18–45 - NCT05585164Recruiting
Therapy program for postpartum depression up to one year
This trial tests a structured talk-therapy program for postpartum depression in the first year after having a baby. It may help by reducing depressive symptoms and improving day-to-day functioning.
New York, New YorkAges Any age - NCT05766475Recruiting
In-person vs virtual postpartum depression prevention groups
This study compares two ways of delivering a group program to help prevent postpartum depression—either in person or online. If you’re pregnant and speak English or Spanish, you may be able to join the program and help researchers learn which format works best.
Denver, ColoradoAges 18 years+ - NCT05772897Recruiting
Parenting group for mothers with postpartum depression
This study offers a structured parenting skills group to help mothers’ mood after having a baby. It also includes some mothers without current depression symptoms for comparison, to better understand what helps.
Denver, ColoradoAges 18–50 - NCT06610552Recruiting
Powerly: Preventing depression and anxiety after childbirth
This trial tests a science-based smartphone program to help prevent postpartum depression and anxiety. It is designed for pregnant women who are between 24 and 32 weeks along and have an iPhone.
ZurichAges 18 years+ - NCT06698107Recruiting
Childbirth education for teen mothers to prevent depression
This program tests a special childbirth education class designed to help first-time teen mothers feel more confident and prepared, with the goal of reducing the chance of depression after the baby is born.
Bahir Dar, AmharaAges 13–19 - NCT06777563Recruiting
Mood app and check-ins to prevent postpartum depression
This study tests whether using a smartphone program (mHealth) along with emotional support (EMA) can help prevent postpartum depression in pregnant women who are feeling distressed. It is for women in Hong Kong who are at 20–28 weeks of pregnancy and have mild to moderate mood symptoms.
Hong Kong, PokfulamAges 18 years+ - NCT06787300Recruiting
Stories that empower mothers and prevent postpartum depression
This study tests a program to support mothers during pregnancy and after childbirth, focusing on preventing or easing postpartum depression. You will join online sessions designed to help you feel more confident and connected.
IzmirAges 18 years+ - NCT06831968Recruiting
Blood test to predict postpartum depression risk
This study tests a new blood test to predict who might get postpartum depression (sadness or mood changes after giving birth). If you are early in your pregnancy (less than 30 weeks), you may be able to join and help find out if the test works.
Charlottesville, VirginiaAges 18 years+ - NCT06833788RecruitingPhase 4
IV vs. oral iron for anemia after c-section and depression risk
This trial compares intravenous (IV) iron with oral iron pills to treat anemia after a C-section, and looks at whether iron treatment affects the risk of postpartum depression. You may be eligible if you had a C-section, are at least 18, delivered at 32 weeks or later, have mild to moderate anemia, and low iron stores.
ParisAges 18 years+ - NCT07384273Recruiting
Online therapy for postpartum depression symptoms
This trial tests an internet-based therapy program (iCARE) to help new mothers manage symptoms of postpartum depression. It may be a good fit if you gave birth within the last 6 months and have been feeling down or depressed.
OdenseAges 18 years+ - NCT06049433Recruiting
Mental health support for new and expecting mothers
This study tests a program to help pregnant women and new mothers who may be at risk for depression after childbirth. The program offers extra support and resources to improve your mental health and well-being.
Salt Lake City, UtahAges 18 years+ - NCT06682689Recruiting
Nerve stimulation study for new mothers' mental health
This study tests whether a gentle nerve stimulation device (tVNS) worn on the ear can help new mothers feel better emotionally after childbirth. It is for women whose babies had normal organ scans and who do not have certain medical conditions or current mood disorders.
Tübingen, Baden-WurttembergAges 18 years+ - NCT07210255Recruiting
SAINT TMS for postpartum depression
This trial tests a special type of TMS (brain stimulation) called SAINT for severe depression that started around childbirth. It may help new mothers who are still within a year postpartum and have not found relief from other treatments.
Worcester, MassachusettsAges 18–45 - NCT07186309Recruiting
At-home test for postpartum depression study
This trial is testing a way to screen for postpartum depression from the comfort of your home. You would take a test during pregnancy to see if it can help find women who may be at risk.
Charlottesville, VirginiaAges 18 years+ - NCT06807801Recruiting
Baby swimming for postpartum depression and bonding
This study looks at whether taking your baby for swimming sessions can help with feelings of depression and strengthen the bond between you and your baby after childbirth.
UppsalaAges 18 years+ - NCT07292649Recruiting
Labor pain relief and postpartum depression risk
This study looks at how your expectations about pain relief during labor might affect your mood after giving birth. Researchers will follow you after delivery to see if there is a link between your hopes for pain management and the risk of postpartum depression.
Padova, VenetoAges 18 years+ - NCT06770244Enrolling by invitation
Positive psychology for postpartum depression in primary care
This trial tests a program based on positive psychology to help prevent or reduce postpartum depression. It is offered within the primary healthcare system and focuses on supporting mothers early in pregnancy.
Wuhan, HubeiAges 18 years+ - NCT06221280Enrolling by invitation
Nerve blocks for pain after cesarean and depression
This study tests whether a nerve block (extra numbing medicine) given during a cesarean section can help with pain after delivery and may reduce the risk of postpartum depression. The trial compares the nerve block to standard care.
Kahramanmaraş, KahramanmaraşAges 18 years+ - NCT06996067Recruiting
Parent coaching texts after first baby in Nova Scotia
This trial tests a text message program to support new parents after childbirth. It aims to help you feel more confident and connected during the early weeks at home.
Halifax, Nova ScotiaAges 18 years+ - NCT06364488Recruiting
App for monitoring depression and anxiety in pregnancy
This trial tests a mobile app called TrueBlue to help monitor depression and anxiety in new and expecting mothers. If you are pregnant or recently gave birth, the study will see if the app can make tracking your moods easier and connect you with care.
Nottingham, NottinghamshireAges 18 years+
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Postpartum Depression trials by city
Studies with a site in or near these metro areas.
Postpartum Depression trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for postpartum depression?
- Yes. Clin2 currently lists 73 recruiting postpartum depression studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a postpartum depression trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a postpartum depression trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.