Clinical trials
Posttraumatic Stress clinical trials
Below are recruiting posttraumatic stress clinical trials, each written for real people, not researchers. We’re tracking 103 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05414708Recruiting
Art therapy for veterans with PTSD symptoms
This study tests whether art therapy can improve emotional well-being in military members who have significant PTSD symptoms. You would answer questionnaires and likely take part in art-making sessions as part of the treatment being studied.
Bethesda, MarylandAges 18–64 - NCT05516277Recruiting
Insomnia care study for older adults with PTSD
This study tests a treatment plan for insomnia (trouble sleeping) in older adults who also have post-traumatic stress disorder (PTSD). The goal is to see whether improving sleep also supports heart and metabolic health (such as blood sugar and heart-related measures).
North Hills, CaliforniaAges 50 years+ - NCT05780177Recruiting
Brief behavioral therapy for insomnia in PTSD veterans
This trial tests a short, structured behavioral program to help improve sleep problems (insomnia) in veterans who also have posttraumatic stress disorder (PTSD). It may help you fall asleep easier and sleep more consistently while continuing your usual care when it’s stable.
San Francisco, CaliforniaAges 18–75 - NCT07060144Recruiting
CPT therapy for PTSD during pregnancy
This trial tests if Cognitive Processing Therapy (CPT), a type of talk therapy, can help pregnant women with PTSD. It aims to reduce PTSD symptoms and improve well-being.
Austin, TexasAges 18–46 - NCT05701111Recruiting
School-based treatment for teens with trauma symptoms
This study tests a school-based approach to help teens who have experienced trauma and now have post-trauma symptoms. It also collects emotional and physical (biologic) information to understand how treatment may help.
Palo Alto, CaliforniaAges 11–17 - NCT06670079Recruiting
Prolonged exposure therapy for PTSD in pregnant patients
This trial tests if prolonged exposure therapy, a type of talk therapy for PTSD, is safe and helpful for pregnant people. If you have PTSD and are early in your pregnancy, this treatment may help you process trauma and feel better.
Burlington, VermontAges 18 years+ - NCT07756723RecruitingPhase 2/Phase 3
Comparing PTSD treatments for veterans with substance use
This study compares two proven treatments for veterans who have both PTSD and substance use problems. It aims to find which treatment works best to help with trauma recovery.
Coatesville, PennsylvaniaAges 18 years+ - NCT05663151Recruiting
Testing how prolonged exposure helps veterans with PTSD
This study looks at why a therapy called prolonged exposure (PE) helps people with PTSD. It includes veterans who want to start PE and checks certain safety and health factors to make sure PE can be used safely.
Boston, MassachusettsAges 18–90 - NCT06746818Enrolling by invitation
Building resilience in older adults with PTSD
This trial tests if a HeartMath-based program can help older adults improve resilience, reduce posttraumatic stress, and boost spiritual and psychosocial well-being. It may be an option if you are 60 or older and have experienced trauma.
Al MansurahAges 60 years+ - NCT03642028RecruitingPhase 4
Sleep medicine study for PTSD-related sleep problems
This trial tests suvorexant, a sleep medicine, to help improve sleep disturbance in people with PTSD. It’s designed for adults who have had PTSD symptoms for at least a few months and also have insomnia.
Long Beach, CaliforniaAges 18–75 - NCT02695953Enrolling by invitation
Study brain changes after trauma-focused therapy for PTSD
This study looks at how the brain works and how it changes after Cognitive Processing Therapy (CPT) for people with PTSD. You might help researchers learn why this therapy helps and who may benefit most.
Belmont, MassachusettsAges 18–55 - NCT07306689Recruiting
PTSD after ectopic pregnancy
This study looks at whether people who have had an ectopic pregnancy (a pregnancy outside the womb) might experience posttraumatic stress disorder (PTSD). It aims to understand emotional impacts and may help improve care.
KrakowAges 18–45 - NCT07106593Recruiting
Talk therapy for PTSD and tinnitus after concussion
This study tests a type of talk therapy for people with both PTSD and chronic tinnitus that started after a mild head injury. The therapy aims to help reduce symptoms of both conditions together.
San Antonio, TexasAges 18 years+ - NCT05517304Recruiting
Noninvasive vagus nerve stimulation for PTSD symptoms
This trial tests whether a noninvasive device that stimulates the vagus nerve through the skin can reduce PTSD symptoms in veterans. It may help calm stress responses without requiring surgery.
Decatur, GeorgiaAges 18–75 - NCT05895006Recruiting
Study brain responses in PTSD using stimulation and brain scans
This study looks at how anxiety and stress show up in the brain in people with PTSD, using brain stimulation and brain scanning. If you’re eligible, it may help researchers understand your symptoms and how they relate to brain activity.
Houston, TexasAges 18–50 - NCT06608277RecruitingPhase 2
Ketamine and nerve block for headache or PTSD after brain injury
This study tests if ketamine infusions or a stellate ganglion block (a numbing injection near the neck) can help people with long-term headaches or PTSD after a traumatic brain injury. It compares these treatments alone and together.
Chicago, IllinoisAges 18 years+ - NCT06989957RecruitingPhase 1
Psilocybin and MDMA therapy for PTSD in veterans
This study tests whether a combination of two investigational drugs, psilocybin and MDMA, can help veterans with post-traumatic stress disorder (PTSD). You would receive the drugs in a controlled setting and be monitored closely.
Baltimore, MarylandAges 21 years+ - NCT05427708Recruiting
Breathing training to reduce anxiety symptoms
This study tests whether specific respiratory (breathing) training can reduce anxiety symptoms and fear responses. It may help people who have several kinds of anxiety or trauma-related anxiety, especially if they are not on anxiety medicines or only stable on them.
Austin, TexasAges 18 years+ - NCT06947538Recruiting
Stepped care for PTSD: a study at Boston Medical Center
This study tests a step-by-step approach to treat posttraumatic stress disorder (PTSD). It aims to help you feel better by offering different treatment options based on your needs.
Boston, MassachusettsAges 18 years+ - NCT06412757RecruitingPhase 3
Silexan for PTSD: A new treatment option
This trial tests a natural treatment called Silexan (an extract from lavender) to see if it helps reduce PTSD symptoms. It might be an option if standard treatments haven't worked or you prefer a non-medication approach.
Carlton, VictoriaAges 18 years+ - NCT06740487Recruiting
AR therapy for PTSD in military members
This study tests a new therapy using augmented reality (a type of headset that adds digital images to what you see) to help treat posttraumatic stress disorder (PTSD) in current or former military members. The therapy aims to make exposure therapy more effective by letting you face trauma-related situations in a controlled, virtual way.
Charleston, South CarolinaAges 18 years+ - NCT07542431Recruiting
How Dog Adoption Helps Veterans With Stress and Mental Health
This study explores whether adopting and training a shelter dog can improve stress symptoms and overall mental health in military veterans. Researchers will follow veterans in the Fort Lauderdale area who adopt dogs through the Humane Society to see if the bond with a trained dog helps their wellbeing.
Boca Raton, FloridaAges 18 years+ - NCT07313280Enrolling by invitation
PTSD and chronic pain therapy study for women
This study looks at how a psychological program can help women with chronic pain conditions linked to central sensitization (where the nervous system stays on high alert) and PTSD. It aims to reduce pain and stress symptoms.
Málaga, MálagaAges 18–65 - NCT07079839Recruiting
Anxiety and stress study for adults with PTSD
This study looks at how the brain processes anxiety and stress in people with PTSD and healthy adults. It uses brain scans and mild electrical stimulation to understand these responses better.
Houston, TexasAges 18–50
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Common questions
- Are there clinical trials for posttraumatic stress?
- Yes. Clin2 currently lists 103 recruiting posttraumatic stress studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a posttraumatic stress trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a posttraumatic stress trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.