Clinical trials
Posttraumatic Stress Disorder (PTSD) clinical trials
Below are recruiting posttraumatic stress disorder (ptsd) clinical trials, each written for real people, not researchers. We’re tracking 94 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05776056RecruitingPhase 4
Methylphenidate for PTSD with memory and thinking problems
This study tests whether methylphenidate, a medication commonly used for attention issues, can help veterans with PTSD who also have memory or concentration problems. The goal is to see if it improves these cognitive symptoms.
Birmingham, AlabamaAges 18–65 - NCT06788678Recruiting
Web-based moral elevation for veterans with PTSD
This trial tests a website designed to help veterans with PTSD feel inspired by stories of others' good deeds, which may reduce PTSD symptoms. You would complete sessions online and answer questions about your experiences.
Temple, TexasAges 18 years+ - NCT07771530RecruitingPhase 2
Medication or dog therapy for PTSD symptoms
This study tests whether a combination of two medications (reboxetine and Ritalin) is more effective than dog-assisted therapy for reducing PTSD symptoms. Participation involves either taking the medications or attending dog therapy sessions.
HaifaAges 18–70 - NCT07382323Recruiting
Comparing two talk therapies for anxiety and PTSD
This trial tests two types of therapy — metacognitive therapy and cognitive-behavioral therapy — to see which works better for people with certain anxiety disorders or PTSD. You would be randomly assigned to one of the treatments and attend regular sessions.
StockholmAges 18 years+ - NCT07756723RecruitingPhase 2/Phase 3
Comparing PTSD treatments for veterans with substance use
This study compares two proven treatments for veterans who have both PTSD and substance use problems. It aims to find which treatment works best to help with trauma recovery.
Coatesville, PennsylvaniaAges 18 years+ - NCT05133804RecruitingPhase 2
Testing two medications for PTSD attention and emotions
This Phase 2 study tests whether reboxetine or methylphenidate can improve attention and emotional or sensory problems in adults with post-traumatic stress disorder (PTSD). You may be eligible if you have a confirmed PTSD diagnosis and are able to meet medication and safety requirements.
AfulaAges 20–60 - NCT06629064Recruiting
Memory training for PTSD symptoms
This study tests a computer-based memory training program for people with PTSD. It aims to see if this training can help reduce PTSD symptoms by improving how your brain processes memories. The study involves 8 remote sessions over 4 weeks and two MRI scans to look at brain changes.
San Diego, CaliforniaAges 18–65 - NCT07227987Recruiting
Cognitive rehab for anger in Veterans with TBI and PTSD
This study tests a cognitive rehabilitation program to help Veterans with TBI and PTSD manage anger. You and a trusted support person will participate together to learn skills to reduce anger and improve thinking.
Durham, North CarolinaAges 18 years+ - NCT06434766Recruiting
Brain stimulation for PTSD treatment study
This study tests a noninvasive brain stimulation method called iTBS to see if it can help people with post-traumatic stress disorder (PTSD). You would receive the treatment and be monitored for changes in your symptoms.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT07707765Recruiting
Early help after sepsis in the ICU to prevent PTSD
This study tests whether early psychological support after sepsis in the ICU can reduce the chance of developing posttraumatic stress disorder (PTSD). If you recently left the ICU after sepsis, you may be able to join.
AshkelonAges 18–120 - NCT03642028RecruitingPhase 4
Sleep medicine study for PTSD-related sleep problems
This trial tests suvorexant, a sleep medicine, to help improve sleep disturbance in people with PTSD. It’s designed for adults who have had PTSD symptoms for at least a few months and also have insomnia.
Long Beach, CaliforniaAges 18–75 - NCT06947538Recruiting
Stepped care for PTSD: a study at Boston Medical Center
This study tests a step-by-step approach to treat posttraumatic stress disorder (PTSD). It aims to help you feel better by offering different treatment options based on your needs.
Boston, MassachusettsAges 18 years+ - NCT04452500RecruitingPhase 2
Study drug for PTSD symptoms in Veterans
This trial tests a study medicine that blocks the effects of cortisol (a stress hormone) to reduce PTSD symptoms in Veterans. It’s meant for people with ongoing PTSD symptoms and stable treatments, and it closely checks safety because the medicine can affect sleep, mood, and heart rhythm.
Tuscaloosa, AlabamaAges 18–69 - NCT04672551Recruiting
EMDR therapy for PTSD after a heart attack
This trial studies whether EMDR (a structured therapy that helps process distressing memories) can reduce PTSD symptoms in people who developed PTSD after a cardiac event. It may help you feel less overwhelmed by memories and stress related to the heart event.
ZurichAges 18–70 - NCT04877093RecruitingPhase 3
Low-dose clonidine for PTSD nightmares in veterans
This Phase 3 study tests whether low-dose clonidine can reduce PTSD symptoms and especially nightmares in U.S. veterans. You’d be screened for PTSD severity and current treatments, then asked to visit the clinic as scheduled to see if the treatment helps.
Wauwatosa, WisconsinAges 18 years+ - NCT04887116RecruitingEarly Phase 1
Virtual reality sessions to treat PTSD in healthcare workers
This early-phase study tests whether guided virtual reality experiences can reduce symptoms of PTSD (post-traumatic stress disorder) or near-PTSD in healthcare workers. It may help people who have stress reactions related to work during the COVID-19 era.
New York, New YorkAges 18 years+ - NCT04959695Recruiting
PE Coach app for veterans with PTSD therapy
This study tests whether a mobile app called “PE Coach” can support PTSD treatment (Prolonged Exposure therapy) for veterans. It may help you stay engaged with therapy sessions done in-person or by video/telehealth using a phone or tablet.
Seattle, WashingtonAges 18–65 - NCT05327504Recruiting
Writing therapy for PTSD and substance use in veterans
This study tests a structured “written exposure” therapy to help veterans with PTSD who also have a substance use disorder (SUD). It may help reduce PTSD symptoms while also supporting safer, more stable recovery.
West Haven, ConnecticutAges 18 years+ - NCT05414708Recruiting
Art therapy for veterans with PTSD symptoms
This study tests whether art therapy can improve emotional well-being in military members who have significant PTSD symptoms. You would answer questionnaires and likely take part in art-making sessions as part of the treatment being studied.
Bethesda, MarylandAges 18–64 - NCT05516277Recruiting
Insomnia care study for older adults with PTSD
This study tests a treatment plan for insomnia (trouble sleeping) in older adults who also have post-traumatic stress disorder (PTSD). The goal is to see whether improving sleep also supports heart and metabolic health (such as blood sugar and heart-related measures).
North Hills, CaliforniaAges 50 years+ - NCT05517304Recruiting
Noninvasive vagus nerve stimulation for PTSD symptoms
This trial tests whether a noninvasive device that stimulates the vagus nerve through the skin can reduce PTSD symptoms in veterans. It may help calm stress responses without requiring surgery.
Decatur, GeorgiaAges 18–75 - NCT05663151Recruiting
Testing how prolonged exposure helps veterans with PTSD
This study looks at why a therapy called prolonged exposure (PE) helps people with PTSD. It includes veterans who want to start PE and checks certain safety and health factors to make sure PE can be used safely.
Boston, MassachusettsAges 18–90 - NCT05701111Recruiting
School-based treatment for teens with trauma symptoms
This study tests a school-based approach to help teens who have experienced trauma and now have post-trauma symptoms. It also collects emotional and physical (biologic) information to understand how treatment may help.
Palo Alto, CaliforniaAges 11–17 - NCT05780177Recruiting
Brief behavioral therapy for insomnia in PTSD veterans
This trial tests a short, structured behavioral program to help improve sleep problems (insomnia) in veterans who also have posttraumatic stress disorder (PTSD). It may help you fall asleep easier and sleep more consistently while continuing your usual care when it’s stable.
San Francisco, CaliforniaAges 18–75
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Posttraumatic Stress Disorder (PTSD) trials by city
Studies with a site in or near these metro areas.
Posttraumatic Stress Disorder (PTSD) trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for posttraumatic stress disorder (ptsd)?
- Yes. Clin2 currently lists 94 recruiting posttraumatic stress disorder (ptsd) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a posttraumatic stress disorder (ptsd) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a posttraumatic stress disorder (ptsd) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.