Clinical trials
Premenstrual Dysphoric Disorder clinical trials
Below are recruiting premenstrual dysphoric disorder clinical trials, each written for real people, not researchers. We’re tracking 8 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06130371Recruiting
Stress, Inflammation & Brain in Depression vs. Severe PMS
This study looks at how stress and inflammation affect the brain in women with major depression compared to women with severe PMS (PMDD). It could help find better ways to understand and treat these mood disorders.
Tübingen, Baden-WurttembergAges 18–40 - NCT06496139Recruiting
Online therapy for emotional symptoms before your period
This study tests an online therapy program to help with intense emotional symptoms before your period. It may be a good fit if you have been diagnosed with PMDD and speak Swedish.
Uppsala, Uppsala CountyAges 18–45 - NCT06648382Recruiting
Thriving with PMDs pilot program
This study tests a new program for people with severe premenstrual mood symptoms, like PMDD or depression that gets worse before your period. It aims to help you feel better and manage your symptoms.
Regina, SaskatchewanAges 18–42 - NCT06704594RecruitingPhase 4
Study of allopregnanolone for PMDD in women on SSRIs
This trial studies a natural brain chemical called allopregnanolone in women with premenstrual dysphoric disorder (PMDD) that responds to SSRI antidepressants. It aims to understand how the brain adapts and whether this treatment could help.
Baltimore, MarylandAges 18–50 - NCT07686718Recruiting
Hormone patterns in PMDD vs. healthy controls
This study compares hormone levels during the luteal phase (the time between ovulation and your period) in people with PMDD versus those without symptoms. It involves collecting a blood sample mid-luteal phase to better understand what causes PMDD.
Lancaster, LancashireAges 18–45 - NCT06771583Recruiting
Finding biomarkers for PMDD in blood samples
This study looks for chemical markers in the blood that might help diagnose PMDD. It involves blood draws and questionnaires over one or two menstrual cycles to see how your body responds to natural hormone changes.
Baltimore, MarylandAges 18–50 - NCT07679074Recruiting
Samphire guided care program for women's mood and brain fog
This 12-week program tests a mobile app and gentle brain stimulation device designed to help women manage mood and thinking problems linked to their menstrual cycle, perimenopause, or menopause. It aims to improve day-to-day well-being, work productivity, and overall quality of life.
San Francisco, CaliforniaAges 18–65 - NCT07688720Recruiting
Ear nerve stimulation for PMDD and perimenopause
This study tests whether a gentle electrical stimulation on the ear can help people with premenstrual dysphoric disorder (PMDD) or perimenopause symptoms. You would use a small device at home and fill out online surveys.
Fort Worth, TexasAges 18–55
Hear when a new Premenstrual Dysphoric Disorder trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for premenstrual dysphoric disorder?
- Yes. Clin2 currently lists 8 recruiting premenstrual dysphoric disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a premenstrual dysphoric disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a premenstrual dysphoric disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.