Clin2
NCT07686718Possibly a fitRecruiting

Hormone patterns in PMDD vs. healthy controls

Premenstrual Dysphoric Disorder ( PMDD)

Part of Mental health clinical trials.

This study compares hormone levels during the luteal phase (the time between ovulation and your period) in people with PMDD versus those without symptoms. It involves collecting a blood sample mid-luteal phase to better understand what causes PMDD.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
50 people
Ages
18 years to 45 years
Study type
Observational

Who can take part

  • Between 18 and 45 years old
  • Regular periods (cycle length 21–35 days for the last 3 months)
  • Willing to use home ovulation test strips and come to Lancaster for one blood test
  • Able to read and understand English without help
  • Either have a prior PMDD diagnosis from a doctor, or have no history of significant premenstrual mood symptoms
  • Not using hormonal birth control, hormone therapy, or certain antidepressants in the last 3 months

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07771426Not yet recruiting
Study on mood symptoms before periods for PMDD and healthy women

This study aims to learn more about premenstrual dysphoric disorder (PMDD), a condition that causes severe mood and physical symptoms before periods. If you experience these symptoms or you do not, you may be able to help by taking part.

London, 'London
NCT06771583Recruiting
Finding biomarkers for PMDD in blood samples

This study looks for chemical markers in the blood that might help diagnose PMDD. It involves blood draws and questionnaires over one or two menstrual cycles to see how your body responds to natural hormone changes.

Baltimore, Maryland
NCT06704594Recruiting· Phase 4
Study of allopregnanolone for PMDD in women on SSRIs

This trial studies a natural brain chemical called allopregnanolone in women with premenstrual dysphoric disorder (PMDD) that responds to SSRI antidepressants. It aims to understand how the brain adapts and whether this treatment could help.

Baltimore, Maryland
NCT06610305Recruiting· Phase 4
Hormones, mood, and reward in women with PMS-related depression

This study looks at how changes in hormone levels during the menstrual cycle affect mood and the brain's reward system in women with depression that gets worse before their period. The goal is to understand why this happens so better treatments can be developed.

Chapel Hill, North Carolina
NCT07189299Not yet recruiting
Microdosing LSD for women with premenstrual disorders

This trial tests whether a very low dose of LSD, taken at specific times, can reduce symptoms of severe premenstrual syndrome (PMS) or premenstrual dysphoric disorder (PMDD). It aims to find a new treatment option for women who have not found relief from other approaches.

Basel, Canton of Basel-City
NCT06648382Recruiting
Thriving with PMDs pilot program

This study tests a new program for people with severe premenstrual mood symptoms, like PMDD or depression that gets worse before your period. It aims to help you feel better and manage your symptoms.

Regina, Saskatchewan

Hear when a new Premenstrual Dysphoric Disorder (PMDD) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.