Clinical trials
Prostate cancer clinical trials
Cancer of the prostate gland, one of the most common cancers in men. We’re tracking 1,219 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06965192Recruiting
Visual tools for cancer surgeon decision-making
This trial tests visual tools to help surgeons make better decisions for patients with early-stage prostate or kidney cancer. It may help you and your doctor choose the best treatment.
Chapel Hill, North CarolinaAges 18 years+ - NCT06659614Recruiting
Prostate tissue collection for future cancer research
This study collects prostate tissue samples from men who are either at higher risk due to a gene change or are getting a biopsy or prostate surgery for routine care. The samples are stored in a biobank for future research on prostate cancer.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07503808RecruitingPhase 1
IDE034 for advanced solid tumors with B7-H3 or PTK7
This study tests a new drug called IDE034 for people with advanced solid tumors that have certain markers (B7-H3 and PTK7). The drug may help by targeting these markers on cancer cells, and the study checks if it is safe and effective.
Denver, ColoradoAges 18 years+ - NCT07557901Enrolling by invitation
Antibiotics to prevent infection after prostate biopsy
This study tests whether taking antibiotics before a prostate biopsy (a needle procedure to check for cancer) reduces infections. You would receive either standard care or a specific antibiotic plan, and researchers will track any infections that develop.
Banská BystricaAges Any age - NCT05183074Recruiting
MRI-guided focused radiation for prostate cancer
This trial tests a newer way to plan and deliver radiation for prostate cancer using real-time MRI guidance. It may help by aiming high-dose treatment precisely while treating nearby disease and (in some cases) limited metastatic spots.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07206056RecruitingPhase 1/Phase 2
Study of tulmimetostat and luxdegalutamide for advanced prostate cancer
This trial tests a new combination of two drugs for men whose prostate cancer has spread and is no longer controlled by hormone therapy. The study aims to see if this treatment can help shrink tumors or slow the disease.
Denver, ColoradoAges 18 years+ - NCT07089550Recruiting
PSMA PET scans to track treatment response in advanced prostate cancer
This study uses a special type of scan called a PSMA PET to see how well different prostate cancer treatments are working. It is for people with advanced prostate cancer who are about to start or change systemic therapy.
Bologna, ItalyAges 18 years+ - NCT06044025RecruitingPhase 1
Maintenance therapy for prostate cancer with rising PSA
This trial tests two medications (metformin and a turmeric compound) as a maintenance therapy for men with prostate cancer whose PSA is rising slowly after prior treatment. The goal is to see if these drugs can keep the cancer from growing while you take a break from standard hormone therapy.
Little Rock, ArkansasAges 18–100 - NCT06866041Recruiting
Prostate cancer markers and imaging for low-risk patients on active surveillance
This trial looks for new markers and advanced scans to better predict which low-risk prostate cancers might grow. If you have low-risk prostate cancer and are managing it with active surveillance, researchers want to see if PSMA-PET scans and tissue markers can give earlier warning of progression.
Milan, ItalyAges 45–80 - NCT03830788Recruiting
Radiation options for early prostate cancer-related erections
This study compares two radiation treatments—seed brachytherapy and stereotactic body radiotherapy—to see which better preserves erections in men with early- to mid-risk prostate cancer. It’s designed to help patients understand how different curative radiation choices can affect sexual function.
AlbiAges 18 years+ - NCT04083937Recruiting
Radiation after prostate surgery for men with prostate cancer
This study looks at different radiation approaches after prostate surgery to see which strategy works best. You may be able to join if your cancer is at a stage where radiation to the prostate bed is planned, and you have not had prior radiation.
HeidelbergAges 18 years+ - NCT05348876RecruitingPhase 4
Darolutamide plus standard hormone therapy for high-risk prostate cancer
This trial studies how safe darolutamide is and how well it works when added to standard hormone therapy for men with high-risk, non-metastatic prostate cancer that is no longer responding to hormone treatment. It may help slow prostate cancer growth and reduce prostate-specific antigen (PSA) rises in real-world care.
Vijayawada, Andhra PradeshAges 18 years+ - NCT05926102Recruiting
Screening study for prostate cancer risk and access
This study looks at how genetic risk and regular screening can help find prostate cancer earlier. It may help you and other Veterans understand what screening is best for different risk levels and access needs.
Boston, MassachusettsAges 55–69 - NCT06064149Recruiting
Heart risk study for men on hormone therapy for prostate cancer
This study looks at heart health in men with prostate cancer who are taking or will take hormone therapy (ADT) for at least 6 months. It aims to learn more about cardiovascular risks and how to manage them.
Philadelphia, PennsylvaniaAges 18 years+ - NCT03972657RecruitingPhase 1/Phase 2
Testing a new prostate and kidney cancer drug with immunotherapy
This early trial tests whether REGN5678 (nezastomig) is safe and how well it works, either by itself or with an immunotherapy drug (cemiplimab). It targets adults with metastatic castration-resistant prostate cancer and certain metastatic kidney cancers that have already been treated.
Gilbert, ArizonaAges 18 years+ - NCT06960798Recruiting
Prostate cancer genetics study in Native Americans
This study looks at the genes of prostate cancer in Native American people. It aims to learn more about the disease in this population by testing stored tumor samples. You can join if you have a prostate cancer diagnosis and have a tumor sample available.
Oklahoma City, OklahomaAges 18–100 - NCT06981377Recruiting
Prostate cancer blood test research study
This study is looking at blood samples from people with prostate cancer to better understand the disease. It may help researchers find new ways to monitor or treat prostate cancer.
Meldola, Forlì-CesenaAges 18 years+ - NCT07432360Recruiting
Finding prostate cancer with advanced MRI and tissue analysis
This trial uses advanced MRI scans and detailed tissue analysis to better detect prostate cancer. It is for people with confirmed prostate cancer who are already scheduled for prostate removal surgery.
São PauloAges 18 years+ - NCT03459820Enrolling by invitationPhase 2/Phase 3
PET/CT scan study for high-risk or returning prostate cancer
This trial studies how a special PET/CT scan (using 18F-DCFPyL) helps evaluate prostate cancer that is either high-risk at diagnosis or has come back based on PSA blood tests. It may help your care team better stage (map) the cancer and guide next steps.
Montreal, QuebecAges 18 years+ - NCT05000294RecruitingPhase 1/Phase 2
Atezolizumab plus tivozanib for hard-to-treat “cold” cancers
This early-stage study tests whether combining atezolizumab and tivozanib can shrink advanced, hard-to-treat cancers that do not strongly activate the immune system (“immunologically cold”). It is for people whose cancer has already been treated or has no good standard options.
Gainesville, FloridaAges 18–99 - NCT03861507Recruiting
Power ultrasound helps locate prostate treatment needles
This trial studies whether a special ultrasound method (power Doppler ultrasound) can better guide where needles go during high-dose-rate radiation treatment for prostate cancer. The goal is to improve targeting during the procedure while you receive standard treatment.
London, OntarioAges 18 years+ - NCT06397755Recruiting
Study of patients with prostate biopsy or prostate removal surgery
This study looks at patients who have had a prostate biopsy or surgery to remove the prostate (radical prostatectomy). It aims to learn more about these procedures and how patients are doing.
MilanAges 18 years+ - NCT06778863RecruitingPhase 1
A study of CLSP-1025 for adults with certain solid tumors
This trial tests a new drug called CLSP-1025 for people with advanced solid tumors that have a specific change in the p53 gene (R175H). The drug targets this change to help fight the cancer.
Scottsdale, ArizonaAges 18 years+ - NCT03784924Recruiting
Prostate MRI study to find blood and urine cancer signals
This study enrolls men who may have prostate cancer but do not yet have a diagnosis. It uses prostate MRI along with blood and urine tests to see if specific signals can help identify prostate cancer sooner.
Ann Arbor, MichiganAges 18 years+
Hear when a new Prostate cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for prostate cancer?
- Yes. Clin2 currently lists 1,219 recruiting prostate cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a prostate cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a prostate cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.