Clinical trials
Prosthesis clinical trials
Below are recruiting prosthesis clinical trials, each written for real people, not researchers. We’re tracking 174 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06388395Enrolling by invitation
Comparison of PEEK and Conventional Dental Prostheses
This study compares two types of full-arch dental prostheses (PEEK and conventional) placed on four implants in the lower jaw, to see which works better. It may be an option if you need all lower teeth replaced and have healthy jawbone.
Sharjah cityAges 18 years+ - NCT05376332Enrolling by invitation
Testing a new arm prosthesis control and training approach
This study is testing different ways to control an arm prosthesis for people missing a hand or lower arm (transradial amputation). It may help compare how well people can use a myoelectric (muscle-signal) prosthesis using either direct control or pattern recognition.
Fairfax, VirginiaAges 18–65 - NCT07432165Recruiting
AI vs. Digital Design for Fixed Dental Prostheses
This study compares artificial intelligence (AI) versus conventional digital methods to design fixed dental prostheses like crowns and bridges. It may help improve how these replacements are created.
GizaAges 18–65 - NCT07632443Recruiting
Testing temporary dental crowns and bridges made of PMMA
This study tests the safety and performance of ON DENT® temporary dental crowns and bridges made from a tooth-colored plastic material called PMMA. If you need a temporary crown or bridge while waiting for a permanent restoration, this trial may help determine how well these temporary options work.
IzmirAges 18 years+ - NCT07645729Recruiting
Testing a Powered Ankle Prosthesis with Neural Control
This study tests a new powered ankle prosthesis (an artificial foot with a motor) that you control using signals from your nerves and receive feedback through gentle stimulation on your skin. The goal is to see if it helps you walk more naturally and perform daily activities with better balance and control.
Cambridge, MassachusettsAges 18–70 - NCT05924386Recruiting
Testing dental implants for jawbone change in full dentures
This study looks at how a specific implant connection (“OT bridge attachment system”) affects changes in the lower jawbone over time in people who have no teeth. You might benefit by getting a fixed All-on-Four style set of lower teeth, with close monitoring of your jawbone and fit.
CairoAges 40 years+ - NCT06158646Recruiting
Comparing knee replacement alignment methods
This study compares two ways to align a total knee replacement (mechanically vs. kinematically) to see which leads to better function one year after surgery. If you've had a knee replacement a year ago and are generally healthy enough to walk without major issues from other leg joints or nervous system problems, you might be eligible.
MérignacAges 18 years+ - NCT07678034Recruiting
Long-term safety study of Tipmed shoulder replacement system
This study checks how safe and effective the Tipmed shoulder replacement system is over time. It is for people who already had this specific shoulder implant during surgery.
BalıkesirAges 18 years+ - NCT07653295Recruiting
Study of Tıpmed revision hip replacement safety
This study follows patients who already had a revision hip replacement using the Tıpmed system. Researchers want to confirm the implant is safe and works well over time.
BalıkesirAges 18 years+ - NCT04200937Enrolling by invitation
Registry for men getting a penile implant
This registry collects information about men who are scheduled for a penile implant approved by Boston Scientific. It helps the doctors and study team understand outcomes over time and improve care for erectile function.
Los Angeles, CaliforniaAges 18 years+ - NCT05574868Recruiting
Inflatable penile implant for erectile dysfunction
This trial tests an inflatable penile implant to treat erectile dysfunction. The device is placed inside the penis and can be inflated to create an erection and deflated when not needed.
AuchenflowerAges 22 years+ - NCT07273773Recruiting
Evaluating a new inflatable penile implant for erectile dysfunction
This trial tests a device called the Infla10®, an inflatable penile implant for men with erectile dysfunction. The goal is to see how well it works and how safe it is.
Coral Gables, FloridaAges 22 years+ - NCT04677907Recruiting
Testing a metal knee implant feature in osteoarthritis surgery
This trial studies a specific type of knee replacement and how well it works after surgery for people with knee osteoarthritis. It may help doctors understand which implant approach leads to better outcomes and recovery.
Glasgow, ScotlandAges 18 years+ - NCT06963242Recruiting
Testing a navigation tool for full-arch dental implants
This trial tests whether a dynamic navigation system helps place dental implants more accurately for people who need a full set of upper or lower teeth. If you are missing most or all of your teeth and are generally healthy, this study may be for you.
Ho Chi Minh CityAges 18 years+ - NCT06853938Recruiting
Optimizing control of a prosthetic arm after osseointegration surgery
This study looks at a new way to control a prosthetic arm after you have had osseointegration surgery (where a metal implant is placed in your bone to attach the arm). It will help find the best settings for the muscle signals that control the arm.
Edmonton, AlbertaAges 18–65 - NCT06321042Recruiting
Knee replacement study using sensor-guided implant placement
This study tests whether using small motion sensors during knee replacement surgery leads to better outcomes. It is for people aged 50–84 with severe knee pain from arthritis or bone damage who are scheduled for a first-time cemented total knee replacement.
Bologna, ItaliaAges 50–85 - NCT05928403Recruiting
Compare knee implant types by how well people return to sport
This study compares three types of knee replacement implants to see how quickly and how well people can return to sports. It may help doctors understand which implant design supports better movement and recovery.
BiarritzAges 18–70 - NCT05175300Recruiting
Vitamin E hip implant for young, active hip replacements
This study tests a hip replacement implant that uses Vitamin E–doped material to see how well it works for young, active adults. It’s meant for people who need a total hip replacement, and compares outcomes over follow-up visits.
LyonAges 18–65 - NCT04692714Recruiting
Cemented vs cement-free robotic knee replacement surgery
This trial compares two ways surgeons can attach a knee replacement using robotic-assisted surgery: with cement or without cement. It may help improve how well the new knee lasts and how patients recover after a first-time knee replacement.
LyonAges 50–80 - NCT06748677Recruiting
Nipple-sparing mastectomy with robotic help and implant reconstruction
This trial tests a newer, less invasive way to remove breast tissue while keeping the nipple and skin, using robotic or endoscopic tools. It then rebuilds the breast with an implant wrapped in a non-biological mesh. The goal is to see how well patients recover and how they feel about the results.
Beijing, Beijing MunicipalityAges Any age - NCT06349629Recruiting
Testing a new dissolving metal implant for joint fractures
This trial tests a new 3D-printed metal implant made of a special magnesium alloy that dissolves over time. It is designed to help mend broken bones near joints, such as wrist, shoulder, or knee fractures, where there is a missing piece of bone.
Beijing, HaidianAges 18–80 - NCT07029880Recruiting
Comparing two types of porcelain for metal-ceramic dental bridges
This study compares two different porcelain materials used to make metal-ceramic dental bridges, to see which works better. It may help you get a stronger, longer-lasting bridge.
CairoAges 21–80 - NCT06160882Recruiting
Powered prosthetic leg for bone-anchored amputees
This study tests a high-tech powered knee and foot for people who have a leg amputation above the knee and have (or are candidates for) a bone-anchored implant. The goal is to see if the powered prosthesis helps with walking and daily activities.
Chicago, IllinoisAges 18–70 - NCT07304115Recruiting
Noise from mechanical heart valve and quality of life
This study looks at how the noise from a mechanical heart valve affects your quality of life after surgery. You will be asked about your memories of the information you received before surgery and how you feel now.
ParisAges 18 years+
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Common questions
- Are there clinical trials for prosthesis?
- Yes. Clin2 currently lists 174 recruiting prosthesis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a prosthesis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a prosthesis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.