Comparing two drugs for sleep in dialysis patients with itch
Treatments studied
Part of Immune system & allergy, Kidney & urinary, Lungs & breathing, Women’s health & pregnancy clinical trials.
This trial tests if anrikefon or nalfurafine improves sleep quality in people on hemodialysis who have chronic kidney disease-related itching. It aims to find a better treatment for both itch and sleep problems.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 75 years old.
- You get regular hemodialysis 3 times a week for end-stage kidney disease.
- You have had itchy skin for at least 6 weeks, with itching on most days.
- Your worst itching in the past week was moderate to severe (score 4 or more on a 0–10 scale).
- You have trouble sleeping (score above 7 on a sleep quality test).
- You have not used certain medications like opioids, gabapentin, pregabalin, or sleep aids recently.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if a medication called nalfurafine hydrochloride (taken as a tablet that melts in your mouth) can help reduce moderate to severe itching in people receiving peritoneal dialysis for chronic kidney disease.
This trial tests a new tablet called nalfurafine to help reduce severe itching that happens in people on regular kidney dialysis. If you've had itching for a while despite trying other treatments, this study may help you and contribute to better options for dialysis patients.
This study tests a medicine called nalfurafine to see if it can reduce severe itching that many people on dialysis have. It will compare the medicine to standard care to find out if it works.
This trial tests a drug called difelikefalin to see if it safely reduces moderate-to-severe itching in teenagers who are on hemodialysis. Itching is common in kidney disease, and this study aims to find a new treatment option.
This trial tests a medication called difelikefalin to relieve severe itching in people on long-term kidney dialysis. Many dialysis patients experience persistent itching that affects their quality of life, and this study explores whether this drug can help.
This Phase 3 study tests whether dupilumab injections can reduce severe itching that has no clear cause. It also checks how safe the medicine is over the study period.
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