Clinical trials
Rheumatic Diseases clinical trials
Below are recruiting rheumatic diseases clinical trials, each written for real people, not researchers. We’re tracking 68 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06806592RecruitingPhase 3
Testing nerandomilast for lung scarring from rheumatic disease
This study tests a new medicine called nerandomilast to see if it can help people with lung scarring caused by autoimmune rheumatic diseases like rheumatoid arthritis or scleroderma. The goal is to slow down lung damage and improve breathing.
Birmingham, AlabamaAges 18 years+ - NCT07469787Recruiting
Transition from pediatric to adult rheumatology care study
This study looks at how to improve the shift from pediatric to adult rheumatology care for young people with chronic inflammatory rheumatic diseases. It aims to understand how healthcare services can better support this transition.
Le Kremlin-BicêtreAges 18 years+ - NCT07716488Recruiting
Screening for high cholesterol in children with chronic conditions
This study screens children and teens with certain chronic conditions (like heart defects or inflammatory bowel disease) for early signs of high cholesterol or other lipid problems. The goal is to find and manage these risks sooner.
JenaAges 6–18 - NCT03813862Recruiting
Study tracking medicines from clinic records
This is an observational study that collects information about what medicines patients receive. It uses data already recorded in participating clinics’ computer health records to better understand medication use over time.
Durham, North CarolinaAges birth+ - NCT04817072Recruiting
Studying mood changes in inflammatory arthritis patients on biologics
This study looks at how mood disorders (like depression or anxiety) affect people with chronic inflammatory joint diseases when they use biologic medicines. It may help doctors understand which patients are at higher mood-risk and how to monitor them.
BesançonAges 18–80 - NCT05007340Recruiting
ILD and autoimmune conditions registry and sample storage
This study collects health information and may store blood or other samples to learn more about interstitial lung disease (ILD) and autoimmune-related conditions. Joining could help researchers understand different causes of ILD and improve future care.
Montreal, QuebecAges 18 years+ - NCT05504928Recruiting
School program to prevent hidden heart valve disease
This study tests whether a prevention program done at a specific school can reduce how common “latent” (hidden) rheumatic heart disease is in children. If you attend the study’s school in Tulsipur, this program may be offered to help protect students’ heart health over time.
Tulsi̇̄purAges 5–16 - NCT06385574Recruiting
Tech-based rehab for rheumatic hand pain
This study tests a technology-based rehab program (like apps or computer exercises) to help people with rheumatic diseases that affect their hands. It aims to improve hand function and reduce pain.
Antalya, KonyaaltıAges 18–64 - NCT06499233RecruitingPhase 4
Study on preventing pneumocystis pneumonia in autoimmune disease
This trial tests whether a preventive treatment can stop pneumocystis pneumonia (a lung infection) in people with autoimmune inflammatory rheumatic diseases who are taking steroids or other immune-suppressing medicines. It aims to find the safest and most effective way to protect you from this serious infection.
Wuhan, HubeiAges 18 years+ - NCT00024479Recruiting
Understanding how rheumatic diseases develop over time
This research study follows people with known or suspected rheumatic diseases (like arthritis, lupus, or similar conditions) to learn how these conditions change and progress naturally. By tracking your health over time, researchers hope to better understand these diseases and improve treatments.
Bethesda, MarylandAges 18–100 - NCT07490041RecruitingEarly Phase 1
CAR-NK cell therapy for refractory childhood rheumatic diseases
This trial is testing a new type of cell therapy (CAR-NK cells) that targets two markers on immune cells (CD19 and BCMA) to treat severe forms of childhood rheumatic diseases. It aims to see if this treatment is safe and can help when other medicines have failed.
Hangzhou, ZhejiangAges 5 years+ - NCT07341386RecruitingPhase 4
Preventing herpes outbreaks in autoimmune rheumatic diseases
This trial tests whether a medicine called acyclovir can prevent herpes simplex outbreaks in people who also have an autoimmune rheumatic disease. It may help reduce the number of painful cold sores or genital herpes episodes you experience.
São Paulo, São PauloAges 12 years+ - NCT05991219Recruiting
Rheumatic heart disease screening and prevention study
This study is looking for people living in rural areas of Sindh, Pakistan, to help screen for and prevent rheumatic heart disease. It aims to find and treat the condition early.
Karachi, SindhAges 10–30 - NCT05443321Enrolling by invitation
Health information sharing during hospital transfers
This trial studies whether sharing patients’ health information between hospitals during transfers can improve outcomes. You may be included if you are moved from a specific partner hospital to Brigham and Women’s Hospital and admitted to certain hospital units.
Boston, MassachusettsAges 18 years+ - NCT07280741RecruitingPhase 4
Shingles vaccine study for people with rheumatic diseases
This study tests the recombinant shingles vaccine in adults with autoimmune rheumatic diseases who are on certain mild medications. It aims to see if the vaccine is safe and effective for them.
São Paulo, São PauloAges 18 years+ - NCT02418442Recruiting
Kid rheumatic disease registry study for follow-up care
This is an observational study that follows children and teens with rheumatic (joint/inflammatory) diseases to better understand how they develop and are cared for over time. You may help by letting the study contact your family in the future and by completing study tasks as needed.
Birmingham, AlabamaAges Up to 21 years - NCT06004349Recruiting
Genetic study of autoinflammatory diseases
This study looks for genes linked to autoinflammatory diseases like VEXAS syndrome. You or your family member can join by mailing in a blood or saliva sample to help researchers better understand these conditions.
New York, New YorkAges 1 month+ - NCT06720272Recruiting
School program to prevent rheumatic heart disease
This study tests whether a program in schools can help prevent rheumatic heart disease in children. If your child is between 5 and 16 years old and attends a participating school, they may be able to join.
KathmanduAges 5–16 - NCT07146048RecruitingPhase 3
Stopping penicillin for early rheumatic heart disease
This trial tests whether it is safe to stop taking daily penicillin for children and teens whose rheumatic heart disease has improved or stayed mild. If you took part in the GOALIE study and your heart condition is now stable, this study may help determine if you can safely stop medication.
Kampala, UGAges 5–20 - NCT06732674Recruiting
Home-based care for lung disease in rheumatic conditions
This trial tests whether people with lung disease caused by a rheumatic condition can safely manage their care at home using a smartphone or tablet. It aims to see if home monitoring is as effective as in-person visits for keeping your lungs healthy.
OsloAges 18 years+ - NCT06413914Recruiting
CBT for long-term pain in rheumatic disease
This trial tests if cognitive behavioral therapy (a type of talk therapy that helps change pain-related thoughts and behaviors) can reduce long-term pain in people with rheumatic diseases. It also validates a new questionnaire (AE-FS) about how pain affects daily life.
OsloAges 18 years+ - NCT07462260RecruitingPhase 2/Phase 3
Sildenafil for severe pulmonary hypertension from rheumatic valve disease
This trial tests if sildenafil can help people with severe pulmonary hypertension caused by rheumatic valvular heart disease. It aims to see if the drug improves symptoms and heart function.
Hyderābād, SindhAges 18 years+ - NCT04556188Recruiting
Study to improve cardiac surgery services for rheumatic heart disease
This study looks at whether building a better, sustainable cardiac surgery service can reduce the burden of rheumatic heart disease. It focuses on patients who need cardiac surgery at a specific hospital during a training and research program.
Addis AbabaAges 14 years+ - NCT05783375Recruiting
Rheumatic heart prevention program for Ugandan communities
This study helps deliver prevention care for rheumatic heart disease in specific districts of northern Uganda. If you live there (or provide care in the selected clinics), the program may offer extra support to help stop heart damage before it starts.
Kampala, UgandaAges 5 years+
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Common questions
- Are there clinical trials for rheumatic diseases?
- Yes. Clin2 currently lists 68 recruiting rheumatic diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a rheumatic diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a rheumatic diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.