Clinical trials
Rheumatoid arthritis clinical trials
An autoimmune condition that causes painful swelling in the joints. We’re tracking 263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06570798RecruitingPhase 2
Testing Two Drugs for Lupus and Rheumatoid Arthritis
This trial tests two study drugs, inebilizumab and blinatumomab, for people with lupus (SLE) or rheumatoid arthritis (RA) that hasn't gotten better with standard treatments. It focuses on those with active disease, especially lupus-related kidney problems.
Scottsdale, ArizonaAges 18–75 - NCT06567470RecruitingPhase 2
Study of CIT-013 for rheumatoid arthritis
This trial tests a new medicine called CIT-013 for people with rheumatoid arthritis. It aims to see if CIT-013 can help reduce joint swelling and pain when added to your current treatment.
AntwerpAges 18 years+ - NCT06579222Recruiting
Managing other health conditions in rheumatoid arthritis
This study looks at how to better manage health conditions like heart disease or diabetes in people with rheumatoid arthritis. Participants will work with their rheumatology clinic to improve overall health.
Waterloo, OntarioAges 18–80 - NCT06528431RecruitingPhase 4
Personalized tapering of adalimumab for rheumatoid arthritis
This study tests if checking the amount of adalimumab (a biologic drug) in your blood can help doctors safely lower your dose. If you have had rheumatoid arthritis under control for at least 6 months, this trial may help you take less medication while keeping symptoms away.
Caluire-et-CuireAges 18 years+ - NCT06426316Recruiting
Immune cells and migraines study
This study looks at how certain immune cells and inflammatory chemicals relate to migraines. If you have migraines or an autoimmune condition (like lupus, rheumatoid arthritis, or Crohn's disease), you may be able to participate. The goal is to understand what causes migraines.
Clermont-Ferrand, AURAAges 18–50 - NCT05926622Recruiting
Testing a Medacta shoulder replacement system for pain relief
This trial studies how well a Medacta shoulder replacement works by looking at clinical results and X-ray/scan findings after surgery. It may help people with certain shoulder conditions who need shoulder replacement or revision surgery.
AnnecyAges 18 years+ - NCT06246123Recruiting
Jyseleca tablet safety study in Korean patients
This study tracks Korean patients already taking Jyseleca for rheumatoid arthritis or ulcerative colitis, making sure it's safe and working as expected. It's not testing a new drug, just watching how patients do over time.
Cheonan, Chungcheongnam-doAges 18 years+ - NCT06072768RecruitingPhase 2
Testing ways to safely lower steroid doses in rheumatoid arthritis
This study compares two different schedules for reducing prednisone (a steroid) in people with rheumatoid arthritis who are also taking another standard arthritis medicine. The goal is to find the safest and most effective way to taper off steroids without causing a flare-up.
Ann Arbor, MichiganAges 18 years+ - NCT05980442Recruiting
Navigation vs robotic-arm assisted knee replacement
This study compares two different high-tech tools used during total knee replacement surgery: one that uses a navigation system (OrthoPilot) and one that uses a robotic arm (MAKO). The goal is to see if one method leads to better results. If you're having a total knee replacement, this trial could help your surgeon choose the best approach.
Ulm, Baden-WurttembergAges 18–90 - NCT05955066RecruitingPhase 4
Testing a JAK inhibitor to help RA joint erosion heal
This Phase 4 study tests whether a JAK inhibitor (baricitinib) can improve how RA-related bone erosion heals. You might be eligible if you have rheumatoid arthritis that is still active despite methotrexate treatment, and you meet the specific safety and medication history rules.
Hong Kong, Hong KongAges 18–65 - NCT05941559Enrolling by invitation
EMDR therapy for long-term rheumatoid arthritis pain
This trial tests whether eye-movement therapy (EMDR) can reduce long-lasting pain in people with rheumatoid arthritis (RA). You may be eligible if your RA has been relatively stable, your pain is still high, and you can take part in therapy sessions safely.
Enschede, OverijsselAges 18 years+ - NCT05587244Enrolling by invitation
Hip liner study for people getting a hip replacement
This study looks at a specific type of hip replacement liner (the part inside the hip joint) and how well it works after surgery. You might be eligible if you’re planning a one-sided hip replacement and don’t have certain infection, bone, or health problems that could affect healing.
Birmingham, AlabamaAges 18–80 - NCT05548972Enrolling by invitation
Follow-up study of a hip replacement to improve implant wear
This study checks how well a specific hip replacement bearing surface (called dual mobility with Vivacit-E or Longevity) performs over time in real-world patients. It may help people by tracking long-term safety and performance to guide better hip replacement choices.
Little Rock, ArkansasAges 18–80 - NCT05277025Recruiting
Brain pain testing in long-term joint pain and fibromyalgia
This study looks at how the brain processes pain in people with long-term pain conditions like fibromyalgia and rheumatoid arthritis. You may be asked to undergo pain-related tasks to help researchers understand differences between inflammatory and non-inflammatory chronic pain.
Gainesville, FloridaAges 18–70 - NCT05302934Recruiting
Testing a knee-surgery app and sensor after knee replacement
This trial checks whether a data platform that uses a wearable sensor and a phone app works well for people getting a total knee replacement. It may help make follow-up care more organized and easier by capturing recovery information.
Konstanz, Baden-WurttembergAges 18 years+ - NCT04899895Enrolling by invitation
Rheumatology sample study for people starting new treatment
This study collects blood or other samples from people with rheumatology (joint/autoimmune) conditions. It looks at changes around the time you start a specific new medicine, which may help researchers understand how treatments work.
Waltham, MassachusettsAges 18 years+ - NCT03276923Recruiting
Pregnancy registry for women with autoimmune disease
This study is a pregnancy and health registry for women with autoimmune (immune system) conditions who are trying to become pregnant or are already pregnant. It helps researchers better understand pregnancy outcomes and health needs in autoimmune disease.
Durham, North CarolinaAges Any age - NCT04692493RecruitingPhase 3
Testing two treatment paths for active rheumatoid arthritis
This Phase 3 study compares two ways to treat active rheumatoid arthritis: a TNF-blocking biologic versus a targeted pill treatment. It may help people who are not doing well on (or cannot tolerate) certain biologic therapies to find a better, more practical option.
Auburn, AlabamaAges 18 years+ - NCT03404778Enrolling by invitation
Collecting data on reverse shoulder implants for weak rotator cuff
This study collects real-world information about a reverse shoulder implant used when the rotator cuff is badly damaged. It may help improve how these implants are chosen and how well they work for pain relief and improving arm function.
Towson, MarylandAges 18 years+ - NCT02748408Recruiting
Long-term follow-up after total hip replacement for severe hip pain
This study tracks people for many years after they get their first total hip replacement due to severe hip problems. It helps doctors understand how well the implant works and how patients recover over time.
ViennaAges 18–75 - NCT01776398Recruiting
Donating breath, blood, and urine samples for lung research
This study collects airway samples (usually during a bronchoscopy), plus blood and/or urine, to help researchers study lung conditions. It may help advance understanding of lung disease and related biology, but it is not a treatment trial.
New York, New YorkAges 18 years+ - NCT02377245Enrolling by invitation
Study of inflammatory rheumatism in youth
This study follows children and teens who have an inflammatory rheumatism condition that started in childhood. It aims to better understand these illnesses and how they affect young people over time.
BrusselsAges Any age - NCT03728478RecruitingPhase 3
Step-up and step-down treatment for newly diagnosed arthritis
This Phase 3 study tests whether children with early juvenile idiopathic arthritis do better by starting with one treatment approach and adjusting (stepping up or stepping down) based on how their arthritis responds. It may help find the safest, most effective long-term plan for controlling symptoms with fewer side effects.
Genova, GEAges 2–17
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Common questions
- Are there clinical trials for rheumatoid arthritis?
- Yes. Clin2 currently lists 263 recruiting rheumatoid arthritis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a rheumatoid arthritis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a rheumatoid arthritis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.