Clinical trials
Schizophrenia Spectrum and Other Psychotic Disorders clinical trials
Below are recruiting schizophrenia spectrum and other psychotic disorders clinical trials, each written for real people, not researchers. We’re tracking 54 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07455929Recruiting
Yoga group therapy for schizophrenia
This trial tests whether a yoga-based group program can help people with schizophrenia spectrum disorders feel better. It's designed for outpatients who are stable enough to participate in group therapy.
BerlinAges 18–65 - NCT07509125Recruiting
Ultra-high resolution PET brain scans for aging, dementia, and psychosis
This study uses a new ultra-high resolution PET scanner to look at brain changes in healthy aging, dementia, ALS, movement disorders, and psychosis. It aims to better understand these conditions and improve imaging techniques.
Leuven, Vlaams-BrabantAges 18–90 - NCT07569471Recruiting
Group compassion therapy for psychosis beliefs
This study tests a new group-based therapy that combines compassion-focused techniques with cognitive behavioral therapy to help people with schizophrenia or related conditions change their beliefs about their psychosis. The goal is to reduce distress and improve how you cope with symptoms.
Scarborough Village, OntarioAges 18 years+ - NCT06792175Enrolling by invitation
Using speech to detect mental health conditions
This study uses a computer program to listen to your speech and see if it can help detect mental health or neurodevelopmental conditions. It may help find new ways to diagnose conditions like ADHD, anxiety, depression, and others earlier.
Brookline, MassachusettsAges 13–60 - NCT05999240RecruitingPhase 2
Pimavanserin for rigid-compulsive symptoms in autism
This trial tests if the drug pimavanserin can help reduce rigid or repetitive behaviors in people with autism spectrum disorder. It may be an option if you or your child struggle with these symptoms and want to try a new treatment.
Lawrence, KansasAges 12–40 - NCT06826326Enrolling by invitationPhase 2
Brain imaging of an antidepressant in teens with autism
This study tests if the antidepressant escitalopram can improve brain function in teenagers with autism. Participants will take the medicine and have brain scans (MRI) to see how it affects brain activity.
Kansas City, KansasAges 12–17 - NCT07265180Recruiting
Oxytocin and group therapy for schizophrenia
This trial tests whether adding oxytocin (a hormone that helps with social bonding) to group therapy can improve symptoms and social functioning in people with schizophrenia. It compares two different doses of oxytocin to see which works better.
Berlin, State of BerlinAges 18–75 - NCT05945602Recruiting
Using brain signals to guide cognitive rehab in psychosis
This study looks at brain-wave or related “brain signal” measurements to better guide cognitive rehabilitation (thinking and memory skills). It may help people with long-term psychotic disorders, and it also may include healthy comparison volunteers to understand the signals.
San Diego, CaliforniaAges 18–75 - NCT07692984Recruiting
Alcohol and drug use in people with schizophrenia or bipolar disorder
This study looks at how alcohol and substance use affects people with schizophrenia or bipolar disorder. It aims to understand if having these conditions together changes treatment or outcomes.
Bolu, BoluAges 18–65 - NCT07329673Recruiting
Testing QbMobile app for ADHD-like symptoms
This trial uses an iPhone app called QbMobile to help tell the difference between ADHD and other conditions like autism, depression, bipolar disorder, or anxiety. It may help people who are not currently being treated for these conditions.
Miami, FloridaAges 6–60 - NCT04631042Recruiting
Study how the brain relates to impulsivity and compulsivity
This study looks at how brain function and structure relate to impulsive and compulsive behaviors. It may help researchers understand what drives these behaviors and who may benefit from future mental health treatments.
Bethesda, MarylandAges 6–80 - NCT07177261Recruiting
Brain synchrony study for schizophrenia
This study looks at how brain activity syncs between people with schizophrenia and others. It aims to understand social interaction differences—potentially leading to better treatments.
Los Angeles, CaliforniaAges 18–65 - NCT07716969Recruiting
Reducing time without treatment for psychosis
This trial tests a program to help people get treatment faster for psychosis. It is for patients who have started OPUS treatment within the last 9 months and may have a schizophrenia-related condition.
Copenhagen, DenmarkAges 18–35 - NCT07234708Recruiting
Feeling Safe Study for people with persecutory delusions
This study tests a psychological treatment for people with schizophrenia who feel unsafe because they believe others are trying to harm them. The goal is to help reduce these fears and improve daily life.
BarcelonaAges 18 years+ - NCT06482554RecruitingPhase 3
Lumateperone for Apathy in Psychotic Disorders
This trial tests a medication called lumateperone to see if it can improve apathy (lack of motivation) in people who have psychotic symptoms from schizophrenia or related disorders. It may help if you are already on a stable treatment but still struggle with apathy.
Shreveport, LouisianaAges 18–65 - NCT07419321Recruiting
Social isolation and aging in schizophrenia study
This study looks at how social isolation affects aging in people with schizophrenia. It may help researchers understand more about the health and well-being of older adults with this condition.
Hartford, ConnecticutAges 40–70 - NCT06726187Recruiting
Autism and personality in adults
This study looks at personality traits and disorders in adults with autism. You and someone who knows you well will answer questions to help researchers understand how autism and personality relate.
RotterdamAges 18 years+ - NCT06575751RecruitingPhase 2
Study of cannabidiol and cannabis concentrate users
This study looks at how cannabidiol (a compound in cannabis) affects people who regularly use strong cannabis concentrates like wax, shatter, or oil. It may help understand if using CBD can change how cannabis affects the body or help with cannabis use disorder.
Aurora, ColoradoAges 25–60 - NCT06781801Recruiting
Heart and metabolic health for severe mental illness
This trial tests a long-term program to improve heart and metabolic health in adults with schizophrenia or related disorders. It may help reduce health risks often linked with severe mental illness.
GothenburgAges 18 years+ - NCT03866668RecruitingPhase 2
Esomeprazole for young children with autism
This Phase 2 study tests whether esomeprazole helps children with autism. It looks at children who are generally healthy, take stable medicines, and can reliably attend visits so their care team can track changes during the study.
Stanford, CaliforniaAges 2–6 - NCT04532424Recruiting
Brain stimulation for repetitive behaviors in autism
This trial tests whether transcranial magnetic stimulation (a non-surgical treatment using magnets on the scalp) can reduce restricted and repetitive behaviors seen in autism. It’s designed for people with autism who have high levels of certain repetitive behaviors, like insistence on sameness or unusual interests.
Stanford, CaliforniaAges 12–45 - NCT05185128Recruiting
Social skills training and brain imaging in teens with autism
This study looks at how social thinking and social skills training affect the brain in teens with autism, compared with teens with other severe mental health conditions and typically developing teens. It may help researchers understand what drives social difficulties and what could improve social functioning.
Loma Linda, CaliforniaAges 12–18 - NCT05501678RecruitingPhase 2
Diphenhydramine to help sleep in autistic children
This Phase 2 study tests whether diphenhydramine improves sleep in children with autism who have significant sleep problems. It requires sleep monitoring (watch data and sleep testing) and checking for side effects to see if the treatment is safe and helpful.
Stanford, CaliforniaAges 8–17 - NCT05540574RecruitingPhase 2
Zolpidem for sleep problems in autistic children
This Phase 2 study tests zolpidem (a sleep medicine) to help children with autism sleep better. It will check sleep changes using sleep testing and to confirm zolpidem is safe for this age group.
Stanford, CaliforniaAges 8–17
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Common questions
- Are there clinical trials for schizophrenia spectrum and other psychotic disorders?
- Yes. Clin2 currently lists 54 recruiting schizophrenia spectrum and other psychotic disorders studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a schizophrenia spectrum and other psychotic disorders trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a schizophrenia spectrum and other psychotic disorders trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.