Clinical trials
Schizophrenia and Schizophrenia Spectrum Psychosis clinical trials
Below are recruiting schizophrenia and schizophrenia spectrum psychosis clinical trials, each written for real people, not researchers. We’re tracking 27 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07192042Recruiting
Testing a device to check sleep breathing in schizophrenia
This trial uses a non-wearable device to assess sleep-disordered breathing in people with schizophrenia who are hospitalized. It aims to understand if this easy method can help monitor sleep issues.
New Taipei CityAges 20–70 - NCT05731414Recruiting
Testing behavior programs to improve outcomes in schizophrenia
This study looks at how a behavioral program (including remediation and behavior-based techniques) may improve outcomes for adults with schizophrenia-spectrum conditions. You may be eligible if you meet basic age/language needs and haven’t done certain therapies recently.
Scarborough Village, OntarioAges 18–65 - NCT06939088RecruitingPhase 2
Tirzepatide for alcohol reduction in schizophrenia
This trial tests if tirzepatide, a once-weekly injection, can help reduce heavy drinking in people who have both schizophrenia and alcohol use disorder. If you struggle with alcohol and have stable schizophrenia, this study may offer a new treatment option.
Aalborg, DenmarkAges 18–70 - NCT07085923Recruiting
Heart health study for people with mental illness
This study tests a program to improve heart health in people with schizophrenia or bipolar disorder who take antipsychotic medication or lithium and have a high body weight. The goal is to help reduce heart disease risk.
OsloAges 25–70 - NCT07234708Recruiting
Feeling Safe Study for people with persecutory delusions
This study tests a psychological treatment for people with schizophrenia who feel unsafe because they believe others are trying to harm them. The goal is to help reduce these fears and improve daily life.
BarcelonaAges 18 years+ - NCT07395206Recruiting
Kiso Mind App for schizophrenia or schizoaffective disorder
This study tests the Kiso Mind app, a smartphone app designed to help people with schizophrenia or schizoaffective disorder manage their symptoms. It looks at whether the app is easy to use and helpful for daily life.
Berlin, State of BerlinAges 18–65 - NCT06740383Recruiting
Study of early psychosis and treatments
This study looks at people who have had psychosis for less than 4 years to understand how their symptoms change over time and how they respond to treatment. By using brain scans and other tests, researchers hope to find better ways to personalize care for early psychosis.
Hartford, ConnecticutAges 18–40 - NCT07252206Recruiting
Culturally adapted CBT for Black people with psychosis
This study offers a talking therapy called culturally adapted cognitive behavioral therapy for psychosis (CBTp) for Black people in the UK who have schizophrenia or related conditions. It aims to see if this approach is helpful and acceptable, and you may join if you are over 16, identify with a Black background, and are not in a current crisis.
ManchesterAges 16 years+ - NCT07569471Recruiting
Group compassion therapy for psychosis beliefs
This study tests a new group-based therapy that combines compassion-focused techniques with cognitive behavioral therapy to help people with schizophrenia or related conditions change their beliefs about their psychosis. The goal is to reduce distress and improve how you cope with symptoms.
Scarborough Village, OntarioAges 18 years+ - NCT07146802Recruiting
Personalized thinking training for psychosis
This trial tests a personalized thinking training program for people with schizophrenia to help reduce symptoms like delusions or suspiciousness. It might be a good fit if you have had some of these symptoms recently and are stable on your current treatment.
StrasbourgAges 18–65 - NCT04368039Recruiting
Breathing regular air pressure oxygen for first-time psychosis
This trial tests whether breathing oxygen (not high-pressure) can improve symptoms in people experiencing a first episode of psychosis. It may help reduce symptoms by changing oxygen delivery to the brain early in the illness.
Columbus, OhioAges 15–35 - NCT03971487RecruitingPhase 1/Phase 2
Ocrelizumab for psychosis linked to an overactive immune system
This Phase 1/2 study tests ocrelizumab, a medicine that affects parts of the immune system, to see if it can improve psychosis symptoms in people with schizophrenia-spectrum disorders. It’s mainly for younger adults with ongoing psychosis and evidence that the symptoms began early in life, with certain infection/vaccine safety requirements.
Houston, TexasAges 18–35 - NCT06341517Recruiting
Brain circuit therapy for schizophrenia
This trial tests a noninvasive brain stimulation treatment (TMS) to improve symptoms of schizophrenia. It aims to target brain circuits that may be out of balance.
GenevaAges 18–65 - NCT06482554RecruitingPhase 3
Lumateperone for Apathy in Psychotic Disorders
This trial tests a medication called lumateperone to see if it can improve apathy (lack of motivation) in people who have psychotic symptoms from schizophrenia or related disorders. It may help if you are already on a stable treatment but still struggle with apathy.
Shreveport, LouisianaAges 18–65 - NCT07263022RecruitingPhase 3
Cognitive Training for Early Psychosis Study
This study tests whether a cognitive training program can help young adults with recent psychosis improve their thinking and memory skills. It involves brain scans and cognitive exercises.
Minneapolis, MinnesotaAges 18–35 - NCT05131035Recruiting
Trial for thinking-speed training to lower psychosis risk
This study targets problems with “processing speed,” or how fast your brain handles information, to see if it can improve social functioning and lower the risk of developing full psychosis. It’s for people who are considered at high risk for psychosis but do not already have schizophrenia.
Glen Oaks, New YorkAges 14–20 - NCT05858255Recruiting
Exergaming program for people with psychosis
This study tests whether an “exergaming” exercise program (video games that make you move) can help people with schizophrenia-spectrum conditions. It’s meant to see if this kind of guided activity is safe and beneficial for symptoms and wellbeing.
Tønsberg, VestfoldAges 18–65 - NCT06191965RecruitingPhase 2/Phase 3
MitoQ supplement for early psychosis
This study tests whether a supplement called MitoQ can help people with early-stage psychosis by improving how their cells produce energy. If you are younger and have been treated for psychosis for less than 5 years, this trial may be an option for you.
New Haven, ConnecticutAges 18–35 - NCT07360665Recruiting
Exercise program for people with psychosis on injectable meds
This trial tests a personalized exercise program for people with psychosis who take long-acting injectable antipsychotics. The goal is to see if regular physical activity can improve overall health and well-being.
Vila RealAges 18 years+ - NCT07716969Recruiting
Reducing time without treatment for psychosis
This trial tests a program to help people get treatment faster for psychosis. It is for patients who have started OPUS treatment within the last 9 months and may have a schizophrenia-related condition.
Copenhagen, DenmarkAges 18–35 - NCT04730518Recruiting
Group yoga program for people with schizophrenia-spectrum disorders
This trial studies whether a structured group yoga program can help people who are currently receiving care for schizophrenia-spectrum disorders. It focuses on patients with low-to-moderate current psychosis and aims to add a supportive therapy alongside usual treatment.
Steglitz, State of BerlinAges 18–90 - NCT06568081Recruiting
Studying a therapy for paranoia in psychosis
This trial tests a therapy for people with psychosis who also experience paranoia. It aims to see if the therapy works and whether it's cost-effective in routine care.
LondonAges 18 years+ - NCT07091344Recruiting
VR-based therapy for voice hearing in schizophrenia
This study tests whether a virtual reality therapy that lets you talk to an avatar of the voice you hear can help reduce distress and improve thinking skills. It's for people with schizophrenia who hear voices regularly and are on stable medication.
Barcelona, CataloniaAges 18 years+ - NCT05185128Recruiting
Social skills training and brain imaging in teens with autism
This study looks at how social thinking and social skills training affect the brain in teens with autism, compared with teens with other severe mental health conditions and typically developing teens. It may help researchers understand what drives social difficulties and what could improve social functioning.
Loma Linda, CaliforniaAges 12–18
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Common questions
- Are there clinical trials for schizophrenia and schizophrenia spectrum psychosis?
- Yes. Clin2 currently lists 27 recruiting schizophrenia and schizophrenia spectrum psychosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a schizophrenia and schizophrenia spectrum psychosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a schizophrenia and schizophrenia spectrum psychosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.