Clinical trials · Dallas–Fort Worth, TX
Schizophrenia clinical trials in Dallas–Fort Worth
We’re tracking 25 recruiting schizophrenia studies with a site in or near Dallas–Fort Worth — including Phase 1, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Dallas–Fort Worth
- NCT06740383Recruiting
Study of early psychosis and treatments
This study looks at people who have had psychosis for less than 4 years to understand how their symptoms change over time and how they respond to treatment. By using brain scans and other tests, researchers hope to find better ways to personalize care for early psychosis.
Dallas, TexasAges 18–40 - NCT06257056Recruiting
Deep brain stimulation for hard-to-treat schizophrenia
This trial tests whether deep brain stimulation (a device that sends electrical pulses to specific areas of the brain) can help people with schizophrenia whose symptoms have not improved with standard treatments. If you have ongoing psychosis and have tried several medications without success, this study may be an option for you.
Dallas, TexasAges 22–70 - NCT07379827Recruiting
A study on switching to KarXT for schizophrenia
This trial looks at how well KarXT works and what side effects it might have when people with schizophrenia switch to it from their current antipsychotic medication. It may be an option for those who have started KarXT recently or who plan to switch from their current treatment.
Dallas, TexasAges 18 years+ - NCT07424404RecruitingPhase 3
Long-term safety trial for teens with schizophrenia or autism irritability
This trial looks at the long-term safety of KarXT, a medication for schizophrenia, and KarX-EC for irritability related to autism in teenagers. It is for teens who have already completed the main part of a previous study without serious side effects.
Dallas, TexasAges 5–17 - NCT04580134RecruitingPhase 4
Clozapine study for people with a specific schizophrenia or bipolar type
This trial tests whether clozapine works better for people whose illness fits a specific “biotype-1” pattern. It may help reduce ongoing symptoms, but it also requires close safety monitoring.
Dallas, TexasAges 18–60 - NCT07098169Recruiting
Testing a program to improve self-awareness for schizophrenia
This trial tests a program called iTEST that helps people with schizophrenia or schizoaffective disorder improve how accurately they understand their own thoughts. The program combines device use with feedback from a clinician or loved one to support better self-awareness.
Dallas, TexasAges 18–65 - NCT01409109Recruiting
Study database for brain signal markers in psychosis
This study builds a database of brain-signal measurements to help find “biomarkers” that may point to schizophrenia or related mental illnesses. Depending on whether you have a mental health diagnosis or you’re healthy, the study will collect information and brain data to compare groups.
Dallas, TexasAges 18–60 - NCT06961968RecruitingPhase 3
Schizophrenia medication withdrawal study
This study tests whether patients with schizophrenia can safely stop or reduce their current medication without worsening symptoms. It is designed for people who need ongoing psychiatric care.
Irving, TexasAges 18–65 - NCT07369154RecruitingPhase 3
Safety of a long-term schizophrenia treatment
This study tests the long-term safety of an investigational medication for schizophrenia over one year. It may be an option if you are currently stable on your antipsychotic medication.
Richardson, TexasAges 18–65 - NCT07615426RecruitingPhase 1
Testing aticaprant with antipsychotic medication for schizophrenia
This study tests whether a new medication called aticaprant is safe and well-tolerated when added to your current antipsychotic medication for schizophrenia. The goal is to see if it could help improve symptoms without causing serious side effects.
Richardson, TexasAges 18–55 - NCT07734493RecruitingPhase 1
Study of a new drug for acute schizophrenia symptoms
This trial tests an experimental medicine, LTX-001, for people with schizophrenia who are currently having a sudden worsening of symptoms. It aims to see if the drug can help reduce these acute symptoms.
Richardson, TexasAges 18–55 - NCT07565428RecruitingPhase 3
Study of roluperidone for negative symptoms of schizophrenia
This trial tests a new medicine called roluperidone for people with schizophrenia who have ongoing negative symptoms (like low motivation or social withdrawal) but stable positive symptoms (like hallucinations). It aims to see if the drug helps with these symptoms and if it can reduce the chance of relapse compared to other medications.
Richardson, TexasAges 18–55 - NCT07459647RecruitingPhase 2
Long-term study of ML-007C-MA for schizophrenia
This trial tests a new drug, ML-007C-MA, for adults with schizophrenia who may benefit from ongoing treatment. It aims to see how safe and effective the drug is over a longer period.
Richardson, TexasAges 18–65 - NCT05184335RecruitingPhase 3
Brilaroxazine for adults with schizophrenia
This study tests whether brilaroxazine works and is safe for people with schizophrenia. It mainly aims to help people whose symptoms are still present despite prior treatment, while excluding those with certain other diagnoses or substance/drug issues.
Richardson, TexasAges 18–65 - NCT06894212RecruitingPhase 3
Testing a new med for schizophrenia flare-ups
This trial tests a new medication called SEP-363856 for people with schizophrenia who are currently having a severe flare-up of symptoms. It aims to see if the drug is safe and effective compared to a placebo.
Richardson, TexasAges 18–65 - NCT07145918RecruitingPhase 2
Study of an oral schizophrenia drug for adults
This trial tests an experimental oral drug (emraclidine) to see if it helps symptoms of schizophrenia and how it moves through the body. It looks at two groups of participants: those with stable symptoms and those having an acute flare-up.
Richardson, TexasAges 18–65 - NCT07680946RecruitingPhase 2
Testing ublituximab for treatment-resistant schizophrenia
This trial tests an experimental drug, ublituximab, to see if it helps people with schizophrenia that hasn't gotten better with standard treatments. It may offer a new option for those who still have significant symptoms despite current therapy.
Richardson, TexasAges 18–60 - NCT07288567RecruitingPhase 3
KarXT for teens with schizophrenia
This trial tests if a new medicine, KarXT, can safely and effectively treat schizophrenia in adolescents. It may help teenagers who have active symptoms like hallucinations or disorganized thinking.
Garland, TexasAges 13–17 - NCT07221877RecruitingPhase 4
Study of KarXT for urological safety in schizophrenia
This study tests a new medicine (KarXT) for schizophrenia, focusing on how it affects urological (bladder and urinary) safety. You'll stop your current antipsychotic and take the study drug to see if it works well and is safe for your urinary system.
DeSoto, TexasAges 18–65 - NCT07410507RecruitingPhase 2
Study of Brenipatide for adults with schizophrenia
This trial tests an investigational drug called brenipatide for people with schizophrenia who are already on a stable medication regimen. The goal is to see if adding this drug helps reduce relapses.
DeSoto, TexasAges 18–55 - NCT07114874RecruitingPhase 3
A long-term study of a new drug for schizophrenia
This study tests a new medicine called NBI-1117568 for adults with schizophrenia over a longer period of time. Participants will stop their current antipsychotics and take this new drug to see how well it works and how safe it is.
DeSoto, TexasAges 18–65 - NCT06963034RecruitingPhase 3
Study of a new medicine for adults with schizophrenia
This trial tests an investigational medicine called NBI-1117568 in adults with schizophrenia who are currently having a relapse or worsening of symptoms and need to stay in the hospital. The goal is to see if the medicine is safe and effective.
DeSoto, TexasAges 18–65 - NCT05025605RecruitingPhase 1
Study medicine for agitation in youth with bipolar or schizophrenia
This Phase 1 trial tests whether BXCL501 is safe and can help reduce agitation in children and teens who have bipolar disorder or schizophrenia. You may be considered if your agitation is significant during screening, but certain recent medication and health factors can make you ineligible.
DeSoto, TexasAges 10–17 - NCT05303064RecruitingPhase 3
Study of weight gain medicine for teens with certain mood or psychosis
This Phase 3 study tests a treatment aimed at reducing unhealthy weight gain in teens with schizophrenia or bipolar I disorder, using changes in BMI (a height-and-weight measure). It may help families who are concerned about weight changes that can happen with some psychiatric medicines.
DeSoto, TexasAges 10–17
Hear when a new Schizophrenia trial opens near Dallas–Fort Worth, TX
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Schizophrenia trials in other cities
Where these studies are running near Dallas–Fort Worth
Institutions with a site for the recruiting schizophrenia studies listed above.
- Pillar Clinical Research · 6 studies
- University of Texas Southwestern Medical Center · 4 studies
- Clinical Site · 3 studies
- Adams Clinical · 2 studies
- InSite Clinical Research · 2 studies
- Local Institution · 2 studies
- Local Institution - Unspecified · 2 studies
- VAST Clinical Research · 2 studies
What taking part in a schizophrenia study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting schizophrenia studies in Texas.
Common questions
- Are there schizophrenia clinical trials near Dallas–Fort Worth?
- Yes. We're currently tracking 25 recruiting schizophrenia studies with a site near Dallas–Fort Worth, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a schizophrenia study near Dallas–Fort Worth?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Dallas–Fort Worth to take part?
- Not necessarily. These studies have a site near Dallas–Fort Worth, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a schizophrenia trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New schizophrenia studies open near Dallas–Fort Worth regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.